Likeness-Based Detection of Sleep Slow Oscillations in Normal and Altered Sleep Conditions: Application on Low-Density EEG Recordings

Sleep slow oscillation (SSO) is a common EEG pattern of spontaneous activity during nonrapid eye movement sleep. A new method for detecting SSOs is presented and compared to previous canonical methods. The main result of this research is that for the first time an extensive SSO analysis is applied to clinical EEG montages, based on low-density EEG recordings. The proposed method gives positive indications about its effectiveness also for altered sleep, extending the SSO analysis to extreme cases, and thus, opening a new front for investigating pathophysiological correlates of sleep disorders.

[1]  B. McEwen Sleep deprivation as a neurobiologic and physiologic stressor: Allostasis and allostatic load. , 2006, Metabolism: clinical and experimental.

[2]  G. Tononi,et al.  Local sleep and learning , 2004, Nature.

[3]  Sean L. Hill,et al.  The Sleep Slow Oscillation as a Traveling Wave , 2004, The Journal of Neuroscience.

[4]  D. Contreras,et al.  The slow (< 1 Hz) oscillation in reticular thalamic and thalamocortical neurons: scenario of sleep rhythm generation in interacting thalamic and neocortical networks , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[5]  A. Rechtschaffen,et al.  A manual of standardized terminology, technique and scoring system for sleep stages of human subjects , 1968 .

[6]  Edward T. Bullmore,et al.  Broadband Criticality of Human Brain Network Synchronization , 2009, PLoS Comput. Biol..

[7]  P. Achermann,et al.  Low-frequency (<1Hz) oscillations in the human sleep electroencephalogram , 1997, Neuroscience.

[8]  A. John Rush,et al.  Slow-wave activity in NREM sleep: sex and age effects in depressed outpatients and healthy controls , 2000, Psychiatry Research.

[9]  M Steriade,et al.  Disconnection of intracortical synaptic linkages disrupts synchronization of a slow oscillation , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[10]  I Feinberg,et al.  Changes in sleep cycle patterns with age. , 1974, Journal of psychiatric research.

[11]  J. Born,et al.  Grouping of Spindle Activity during Slow Oscillations in Human Non-Rapid Eye Movement Sleep , 2002, The Journal of Neuroscience.

[12]  P. Prinz,et al.  Age trends in the sleep EEG of healthy older men and women , 1995, Journal of sleep research.

[13]  Heidi Danker-Hopfe,et al.  Age-related changes in sleep and memory: commonalities and interrelationships , 2005, Experimental Gerontology.

[14]  Marcello Massimini,et al.  Sleep homeostasis and cortical synchronization: III. A high-density EEG study of sleep slow waves in humans. , 2007, Sleep.

[15]  M. Steriade,et al.  Neuronal Plasticity in Thalamocortical Networks during Sleep and Waking Oscillations , 2003, Neuron.

[16]  D. Contreras,et al.  Cortically-induced coherence of a thalamic-generated oscillation , 1999, Neuroscience.

[17]  Khaled H. Hamed,et al.  Time-frequency analysis , 2003 .

[18]  J. Born,et al.  Boosting slow oscillations during sleep potentiates memory , 2006, Nature.

[19]  Arnaud Delorme,et al.  EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis , 2004, Journal of Neuroscience Methods.

[20]  J. Wolpaw,et al.  EMG contamination of EEG: spectral and topographical characteristics , 2003, Clinical Neurophysiology.

[21]  M Steriade,et al.  Intracellular analysis of relations between the slow (< 1 Hz) neocortical oscillation and other sleep rhythms of the electroencephalogram , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[22]  Angelo Gemignani,et al.  Event-driven power-law relaxation in weak turbulence: A liquid crystals mesoscopic experiment bridging quantum dots and the integration theory for the brain , 2009 .

[23]  I Feinberg,et al.  EEG sleep patterns as a function of normal and pathological aging in man. , 1967, Journal of psychiatric research.

[24]  E. Wolpert A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. , 1969 .