Characteristic Epithelium with Low‐Grade Atypia Appears on the Surface of Gastric Cancer after Successful Helicobacter pylori Eradication Therapy

The incidence of gastric cancer after successful Helicobacter pylori eradication has been increasing. We previously reported that epithelium with low‐grade atypia (ELA) appeared on the surface of gastric cancer after H. pylori eradication. Here, we investigate the clinical and biological characteristics of such ELA.

[1]  K. Chayama,et al.  Advanced Method for Evaluation of Gastric Cancer Risk By Serum Markers: Determination of True Low‐Risk Subjects for Gastric Neoplasm , 2014, Helicobacter.

[2]  M. Takeuchi,et al.  Magnifying narrow-band imaging of surface maturation in early differentiated-type gastric cancers after Helicobacter pylori eradication , 2013, Journal of Gastroenterology.

[3]  K. Chayama,et al.  Gastric Cancer Development after Helicobacter pylori Eradication Therapy: A New Form of Gastric Neoplasia , 2012, Digestion.

[4]  K. Chayama,et al.  Low Prevalence of Helicobacter pylori‐negative Gastric Cancer among Japanese , 2011, Helicobacter.

[5]  H. Matsumoto,et al.  Long-term clinical outcome of gastric MALT lymphoma after eradication of Helicobacter pylori: a multicentre cohort follow-up study of 420 patients in Japan , 2011, Gut.

[6]  Y. Matsuno,et al.  Clinicopathological Analysis of Early‐Stage Gastric Cancers Detected After Successful Eradication of Helicobacter pylori , 2011, Helicobacter.

[7]  K. Chayama,et al.  Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review , 2009, Journal of Gastroenterology.

[8]  M. Asaka,et al.  Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial , 2008, The Lancet.

[9]  K. Chayama,et al.  Host factors contributing to the discovery of gastric cancer after successful eradication therapy of Helicobacter pylori: Preliminary report , 2007, Journal of gastroenterology and hepatology.

[10]  Y. Naito,et al.  Biomarkers in Patients with Gastric Inflammation: A Systematic Review , 2005, Digestion.

[11]  K. Chayama,et al.  Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short‐term follow‐up , 2005, Alimentary pharmacology & therapeutics.

[12]  K. Haruma,et al.  Evaluation of tumor growth rate in patients with early gastric carcinoma of the elevated type , 2005, Gastrointestinal Radiology.

[13]  K. Chayama,et al.  Mucin Phenotype and Background Mucosa of Intramucosal Differentiated-Type Adenocarcinoma of the Stomach , 2004, Oncology.

[14]  S. Kitano,et al.  Re‐evaluation of mucin phenotypes of gastric minute well‐differentiated‐type adenocarcinomas using a series of HGM, MUC5AC, MUC6, M‐GGMC, MUC2 and CD10 stains , 2004, Pathology international.

[15]  R. P. Blankfield,et al.  Helicobacter pylori infection and the development of gastric cancer. , 2001, The New England journal of medicine.

[16]  L. Hansson,et al.  Helicobacter pylori in gastric cancer established by CagA immunoblot as a marker of past infection. , 2001, Gastroenterology.

[17]  N. Sasaki,et al.  Helicobacter pylori infection and the development of gastric cancer. , 2001, The New England journal of medicine.

[18]  A. Oshima,et al.  Natural history of early gastric cancer: a non-concurrent, long term, follow up study , 2000, Gut.

[19]  H. Ono,et al.  Endoscopic and histological reversibility of gastric adenoma after eradication of Helicobacter pylori. , 1999, Journal of gastroenterology.

[20]  T. Sakurazawa,et al.  Disappearance of Hyperplastic Polyps in the Stomach after Eradication of Helicobacter pylori , 1998, Annals of Internal Medicine.

[21]  H. Nagai,et al.  Helicobacter pylori infection induces gastric cancer in mongolian gerbils. , 1998, Gastroenterology.

[22]  S. Kawasaki,et al.  Helicobacter pylori infection enhances N-methyl-N-nitrosourea-induced stomach carcinogenesis in the Mongolian gerbil. , 1998, Cancer research.

[23]  胃癌研究会.  Japanese classification of gastric carcinoma , 1995 .

[24]  M. Blaser,et al.  Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. , 1991, The New England journal of medicine.

[25]  T. Takemoto,et al.  An Endoscopic Recognition of the Atrophic Border and its Significance in Chronic Gastritis , 1969 .