Alterations in the Intestinal Mucosal Structure Following Oral Administration of Triiodothyronine (T3) in Broiler Chickens

Abstract Teshfam, M., Nodeh, H. and Hassanzadeh, M. 2005. Alterations in the intestinal mucosal structure following oral administration of triiodothyronine (T3) in broiler chickens. J. Appl. Anim. Res., 27: 105–108. It had been shown that in response to thyroxine administration, some structural changes can occur in the mucosa of the intestine. These changes are specially imposed on the proliferation and differentiation of the intestinal cells. To study this, one hundred and fifty chickens were randomly divided into two equal groups and the diet of one of them was supplemented with 1.5 ppm T3. At the end of 6th week T3 administration decreased intestinal villus height in the duodenum and increased the intestinal crypt depth, which seemed to be the sign of increase in cell proliferation. The number of leaf-shaped villi was significantly reduced while that of the tongue-shaped villi significantly increased hroughout the intestine in T3-treated group.

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