First Trimester Uterine Artery Doppler, Placental Volume and Ductus Venosus Blood Flow as Predictors of Third Trimester Fetal Growth Parameters

To evaluate the potentials of the first trimester uterine artery Doppler, placental volume measurement and ductus venosus blood flow as predictors of third trimester fetal growth parameters. This study was a prospective-observational study, conducted on 200 pregnant women, during a period of 2 years starting from June 1st 2013 till May 30th 2015, in order to evaluate the potentials of the first trimester uterine artery doppler, placental volume measurement and ductus venous blood flow as predictors of third trimester fetal growth parameters, as well as to determine whether these measurements are independent or not in the prediction of fetal growth restriction. First trimester uterine artery pulsatility index (PI) was found to have a negative correlation with third trimester BPD, HC, AC and FL, as well as with fetal birth weight. First trimester placental volume was found to have a positive correlation with third trimester HC, AC and FL but not with BPD. No correlation was found between first trimester placental volume and fetal birth weight. First trimester ductus venosus Doppler indices (PI and PVIV) were found to have no correlation with third trimester fetal growth parameters (BPD, HC, AC and FL), which was later confirmed at birth.

[1]  H. Fox,et al.  Pathology of the Placenta , 2019, Springer International Publishing.

[2]  M. Tuuli,et al.  Placental volume and vascular flow assessed by 3D power Doppler and adverse pregnancy outcomes. , 2011, Placenta.

[3]  Samuel Parry,et al.  Novel 3‐Dimensional Placental Measurements in Early Pregnancy as Predictors of Adverse Pregnancy Outcomes , 2010, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[4]  K. Nicolaides,et al.  Hypertensive disorders in pregnancy: combined screening by uterine artery Doppler, blood pressure and serum PAPP‐A at 11–13 weeks , 2010, Prenatal diagnosis.

[5]  C F A Peralta,et al.  Placental volume measured by three‐dimensional ultrasound at 11 to 13 + 6 weeks of gestation: relation to chromosomal defects , 2005, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[6]  Jason Gardosi,et al.  Perinatal mortality and fetal growth restriction. , 2004, Best practice & research. Clinical obstetrics & gynaecology.

[7]  K. Nicolaides,et al.  The role of uterine artery Doppler in predicting adverse pregnancy outcome. , 2004, Best practice & research. Clinical obstetrics & gynaecology.

[8]  Gordon C. S. Smith.  First trimester origins of fetal growth impairment. , 2004, Seminars in perinatology.

[9]  F. Prefumo,et al.  First‐trimester uterine artery blood flow and birth weight , 2003, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[10]  B. Thilaganathan,et al.  The human ductus venosus between 13 and 17 weeks of gestation: histological and morphometric studies , 2002, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[11]  D. Altman,et al.  Charts of fetal size: 4. Femur length , 1994, British journal of obstetrics and gynaecology.

[12]  L. R. Hellevik,et al.  Ultrasonographic velocimetry of the fetal ductus venosus , 1991, The Lancet.

[13]  E. Guzman,et al.  A classification of hypertension in pregnancy based on Doppler velocimetry. , 1987, American journal of obstetrics and gynecology.

[14]  A. Rudolph.  Distribution and regulation of blood flow in the fetal and neonatal lamb. , 1985, Circulation research.

[15]  Peter D. Gluckman,et al.  Regulation of Fetal Growth , 1984 .

[16]  S. Campbell,et al.  ULTRASOUND MEASUREMENT OF THE FETAL HEAD TO ABDOMEN CIRCUMFERENCE RATIO IN THE ASSESSMENT OF GROWTH RETARDATION , 1977, British Journal of Obstetrics and Gynaecology.