Sequential and Selective Self-Assembly of Micro Components by DNA Grafted Polymer

We demonstrated that Deoxyribonucleic Acid (DNA) can be utilized as an intelligent adhesive activated by temperature control to realize sequential and selective self-assembly of 5 mm squared silicon micro components on a substrate. Two kinds of complementary DNA pairs whose melting transition temperature (Tm) and base sequence were designated appropriately were utilized to verify the feasibility of the proposed approach. It was successfully confirmed that sequential and selective assembly of micro components on the substrate can be realized below each Tm. Furthermore, DNA grafted polymer was proposed for the first time as a flexible spacer between micro components and a substrate to improve self-assembly yield and speed.

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