Theory of Mind Performance in Schizophrenia: Diagnostic, Symptom, and Neuropsychological Correlates

The purpose of this study was to explore the relationship between Theory of Mind (ToM) performance and schizophrenia subtype, symptom, and neuropsychological variables. One hundred twenty-eight stable outpatients with schizophrenia or schizoaffective disorder were assessed during the intake phase of a vocational and cognitive rehabilitation study. Results indicate that ToM performance differed significantly by schizophrenia diagnosis, with people diagnosed with disorganized schizophrenia performing the most poorly. Theory of Mind performance was also significantly correlated with measures of thought disorder and verbal memory. Regression analysis revealed that thought disorder and verbal memory measures explained 30% of the variance in ToM scores. Findings suggest that there is theory of mind variance in the schizophrenia population and theory of mind is strongly related to thought disorder, verbal memory, and cognitive disorganization. Contrary to previous reports, ToM was not related to measures of paranoia.

[1]  J. Jolles,et al.  The Neuropsychology of Schizophrenia , 2019 .

[2]  Udi Bonshtein,et al.  [Theory of mind in schizophrenia]. , 2006, Harefuah.

[3]  B. Wexler,et al.  Neurocognitive enhancement therapy with work therapy: effects on neuropsychological test performance. , 2001, Archives of general psychiatry.

[4]  M. Casacchia,et al.  Selective impairments of theory of mind in people with schizophrenia , 2001, Schizophrenia Research.

[5]  C. Frith,et al.  Theory of mind impairments in schizophrenia: symptomatology, severity and specificity , 2001, Psychological Medicine.

[6]  A. Klin.  Attributing social meaning to ambiguous visual stimuli in higher-functioning autism and Asperger syndrome: The Social Attribution Task. , 2000, Journal of child psychology and psychiatry, and allied disciplines.

[7]  P. Garety,et al.  Cognitive approaches to delusions: a critical review of theories and evidence. , 1999, The British journal of clinical psychology.

[8]  Y. Sarfati,et al.  How do people with schizophrenia explain the behaviour of others? A study of theory of mind and its relationship to thought and speech disorganization in schizophrenia , 1999, Psychological Medicine.

[9]  J. Gray,et al.  Comprehension of irony in Schizophrenia , 1998 .

[10]  C. Frith,et al.  Theory of mind and psychoses , 1998, Psychological Medicine.

[11]  C. Frith,et al.  The appreciation of visual jokes in people with schizophrenia: a study of ‘mentalizing’ ability , 1997, Schizophrenia Research.

[12]  R. Frith.  Conversational conduct and the symptoms of schizophrenia. , 1996, Cognitive neuropsychiatry.

[13]  C. Frith,et al.  Exploring ‘theory of mind’ in people with schizophrenia , 1996, Psychological Medicine.

[14]  M. Bell,et al.  Five-component model of schizophrenia: Assessing the factorial invariance of the positive and negative syndrome scale , 1994, Psychiatry Research.

[15]  J. Morton,et al.  The cognitive basis of a biological disorder: autism , 1991, Trends in Neurosciences.

[16]  P F Liddle,et al.  Schizophrenic Syndromes and Frontal Lobe Performance , 1991, British Journal of Psychiatry.

[17]  P. Liddle.  The Symptoms of Chronic Schizophrenia , 1987, British Journal of Psychiatry.

[18]  A. Silverstein.  Two- and Four-Subtest Short Forms of the Wechsler Adult Intelligence Scale-Revised. , 1982 .

[19]  J. Carbonell,et al.  Clinical artificial intelligence , 1981, Behavioral and Brain Sciences.

[20]  D. Premack,et al.  Does the chimpanzee have a theory of mind? , 1978, Behavioral and Brain Sciences.

[21]  D. R. Gorham,et al.  Use of the proverbs test for differentiating schizophrenics from normals. , 1956, Journal of consulting psychology.

[22]  D. Penn,et al.  Social cognition and schizophrenia. , 2001 .

[23]  J. McGrath,et al.  The cognitive neuropsychology of schizophrenia. , 1997 .

[24]  R. Heaton.  Wisconsin Card Sorting Test manual , 1993 .

[25]  R. Reitan.  Trail Making Test: Manual for Administration and Scoring , 1992 .

[26]  S. Ganzell,et al.  Wisconsin Card Sorting Test performance in schizophrenia: remediation of a stubborn deficit. , 1992, The American journal of psychiatry.

[27]  J. Brandt.  The Hopkins Verbal Learning Test: Development of a new memory test with six equivalent forms. , 1991 .

[28]  Robert A. Bornstein,et al.  The Wechsler Memory Scale—Revised , 1990 .

[29]  U. Frrrh.  Autism: explaining the enigma , 1989 .

[30]  D. Wechsler.  WAIS-R manual : Wechsler adult intelligence scale-revised , 1981 .