Release of immunomodulatory peptides at bacterial membrane interfaces as a novel strategy to fight microorganisms.

[1]  M. Brönstrup,et al.  Selective Bacterial Targeting and Infection‐Triggered Release of Antibiotic Colistin Conjugates , 2021, Angewandte Chemie.

[2]  C. G. Hansen,et al.  Immune complex-induced apoptosis and concurrent immune complex clearance are anti-inflammatory neutrophil functions , 2021, Cell Death & Disease.

[3]  Arlindo L. Oliveira,et al.  Characterization of novel human intragenic antimicrobial peptides, incorporation and release studies from ureasil-polyether hybrid matrix. , 2021, Materials science & engineering. C, Materials for biological applications.

[4]  E. Brennan,et al.  Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential. , 2021, European journal of medicinal chemistry.

[5]  S. Bobone,et al.  Inoculum effect of antimicrobial peptides , 2020, Proceedings of the National Academy of Sciences.

[6]  F. Goñi,et al.  A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis , 2020, Nature Communications.

[7]  M. Poręba Protease‐activated prodrugs: strategies, challenges, and future directions , 2020, The FEBS journal.

[8]  Dianqing Wu,et al.  Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization , 2020, The Journal of Immunology.

[9]  C. Bloch,et al.  Intragenic antimicrobial peptides (IAPs) from human proteins with potent antimicrobial and anti-inflammatory activity , 2019, PloS one.

[10]  Ernest Y Lee,et al.  Unifying structural signature of eukaryotic α-helical host defense peptides , 2019, Proceedings of the National Academy of Sciences.

[11]  Dorothee Kretschmer,et al.  Formyl-Peptide Receptors in Infection, Inflammation, and Cancer. , 2018, Trends in immunology.

[12]  Elif Ozkirimli,et al.  Membrane Active Peptides and Their Biophysical Characterization , 2018, Biomolecules.

[13]  C. Dahlgren,et al.  Formyl Peptide Receptors in Mice and Men: Similarities and Differences in Recognition of Conventional Ligands and Modulating Lipopeptides. , 2018, Basic & clinical pharmacology & toxicology.

[14]  C. Bloch,et al.  Towards an experimental classification system for membrane active peptides , 2018, Scientific Reports.

[15]  A. Klos,et al.  Formyl‐peptide receptor 2 governs leukocyte influx in local Staphylococcus aureus infections , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[16]  W. Wimley,et al.  Antimicrobial peptides are degraded by the cytosolic proteases of human erythrocytes. , 2017, Biochimica et biophysica acta. Biomembranes.

[17]  T. Renné,et al.  The plasma contact system, a protease cascade at the nexus of inflammation, coagulation and immunity. , 2017, Biochimica et biophysica acta. Molecular cell research.

[18]  N. Metzler‐Nolte,et al.  Highly Potent Antibacterial Organometallic Peptide Conjugates. , 2017, Accounts of chemical research.

[19]  R. Hoffmann,et al.  Differential stability of therapeutic peptides with different proteolytic cleavage sites in blood, plasma and serum , 2017, PloS one.

[20]  Yoonkyung Park,et al.  Cell-Density Dependence of Host-Defense Peptide Activity and Selectivity in the Presence of Host Cells. , 2017, ACS chemical biology.

[21]  W. Luyten,et al.  Molecular mechanisms of LL-37-induced receptor activation: An overview , 2016, Peptides.

[22]  M. Hollenberg,et al.  Proteinases, Their Extracellular Targets, and Inflammatory Signaling , 2016, Pharmacological Reviews.

[23]  I. Neundorf,et al.  Design and Application of Antimicrobial Peptide Conjugates , 2016, International journal of molecular sciences.

[24]  W. S. Horne,et al.  Peptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution , 2016, Chembiochem : a European journal of chemical biology.

[25]  X. Bian,et al.  New development in studies of formyl‐peptide receptors: critical roles in host defense , 2016, Journal of leukocyte biology.

[26]  T. Muir,et al.  Regulation of Virulence in Staphylococcus aureus: Molecular Mechanisms and Remaining Puzzles. , 2016, Cell chemical biology.

[27]  M. Zhang,et al.  Bacteria-Targeting Conjugates Based on Antimicrobial Peptide for Bacteria Diagnosis and Therapy. , 2015, Molecular pharmaceutics.

[28]  Benhur Lee,et al.  Broad-spectrum antivirals against viral fusion , 2015, Nature Reviews Microbiology.

[29]  Tim J. Stevens,et al.  Structure calculation, refinement and validation using CcpNmr Analysis , 2015, Acta crystallographica. Section D, Biological crystallography.

[30]  K. Lohner,et al.  The role of spontaneous lipid curvature in the interaction of interfacially active peptides with membranes. , 2014, Biochimica et biophysica acta.

[31]  Thomas Ebenhan,et al.  Antimicrobial Peptides: Their Role as Infection-Selective Tracers for Molecular Imaging , 2014, BioMed research international.

[32]  Tudor I. Oprea,et al.  Antibacterial Activity of Pepducins, Allosterical Modulators of Formyl Peptide Receptor Signaling , 2014, Antimicrobial Agents and Chemotherapy.

[33]  J. Kahlenberg,et al.  Little Peptide, Big Effects: The Role of LL-37 in Inflammation and Autoimmune Disease , 2013, The Journal of Immunology.

[34]  A. Miranker,et al.  A common landscape for membrane‐active peptides , 2013, Protein science : a publication of the Protein Society.

[35]  R. Ammendola,et al.  Distinct Signaling Cascades Elicited by Different Formyl Peptide Receptor 2 (FPR2) Agonists , 2013, International journal of molecular sciences.

[36]  Liliane Schoofs,et al.  A comprehensive summary of LL-37, the factotum human cathelicidin peptide. , 2012, Cellular immunology.

[37]  T. Renné,et al.  Crosstalk of the plasma contact system with bacteria. , 2012, Thrombosis research.

[38]  A. Cooper,et al.  Probing Protein Sequences as Sources for Encrypted Antimicrobial Peptides , 2012, PloS one.

[39]  M. Imran,et al.  Antimicrobial Peptides as Infection Imaging Agents: Better Than Radiolabeled Antibiotics , 2012, International journal of peptides.

[40]  D. Zamboni,et al.  A Method for Generation of Bone Marrow-Derived Macrophages from Cryopreserved Mouse Bone Marrow Cells , 2010, PloS one.

[41]  S. Ryu,et al.  The Agonists of Formyl Peptide Receptors Prevent Development of Severe Sepsis after Microbial Infection , 2010, The Journal of Immunology.

[42]  J. Barnett,et al.  Interleukin 12 a Key Immunoregulatory Cytokine in Infection Applications , 2010, International journal of molecular sciences.

[43]  Sun Young Lee,et al.  Functional Expression of Formyl Peptide Receptor Family in Human NK Cells1 , 2009, The Journal of Immunology.

[44]  A. Miranker,et al.  The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes. , 2009, Annual review of biophysics.

[45]  A. Brunger Version 1.2 of the Crystallography and NMR system , 2007, Nature Protocols.

[46]  X. Wang,et al.  Discovery of Trp-Nle-Tyr-Met as a novel agonist for human formyl peptide receptor-like 1. , 2007, Biochemical pharmacology.

[47]  Michael Nilges,et al.  ARIA2: Automated NOE assignment and data integration in NMR structure calculation , 2007, Bioinform..

[48]  C. Brouwer,et al.  Synthetic peptides derived from human antimicrobial peptide ubiquicidin accumulate at sites of infections and eradicate (multi-drug resistant) Staphylococcus aureus in mice , 2006, Peptides.

[49]  J. Nicolas,et al.  Determination of Plasma Trypsin-Like Activity in Healthy Subjects, Patients With Mild to Moderate Alcoholic Chronic Pancreatitis, and Patients With Nonjaundice Pancreatic Cancer , 2005, Digestive Diseases and Sciences.

[50]  Wayne Boucher,et al.  The CCPN data model for NMR spectroscopy: Development of a software pipeline , 2005, Proteins.

[51]  M. Imran,et al.  Antimicrobial peptide 99mTc-ubiquicidin 29-41 as human infection-imaging agent: clinical trial. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[52]  K. Shoemaker,et al.  Substrate Specificity of the Escherichia coli Outer Membrane Protease OmpP , 2006, Journal of bacteriology.

[53]  G. Ji,et al.  Membrane Anchoring of the AgrD N-terminal Amphipathic Region Is Required for Its Processing to Produce a Quorum-sensing Pheromone in Staphylococcus aureus* , 2004, Journal of Biological Chemistry.

[54]  Sung Ho Ryu,et al.  Differential Activation of Formyl Peptide Receptor-Like 1 by Peptide Ligands 1 , 2003, The Journal of Immunology.

[55]  J. Kwak,et al.  Differential signaling of formyl peptide receptor-like 1 by Trp-Lys-Tyr-Met-Val-Met-CONH2 or lipoxin A4 in human neutrophils. , 2003, Molecular pharmacology.

[56]  Michael R. Yeaman,et al.  Mechanisms of Antimicrobial Peptide Action and Resistance , 2003, Pharmacological Reviews.

[57]  C. Dahlgren,et al.  The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH2 Specifically Activates Neutrophils through FPRL1/Lipoxin A4 Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2* , 2001, The Journal of Biological Chemistry.

[58]  A. Husband,et al.  Effects of Exogenous Interleukin-6 duringPseudomonas aeruginosa Corneal Infection , 2001, Infection and Immunity.

[59]  V. Gerke,et al.  A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR. , 2000, Molecular cell.

[60]  W. Chan,et al.  Fmoc solid phase peptide synthesis : a practical approach , 2000 .

[61]  J. Waitz Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically , 1990 .

[62]  R. Epand,et al.  A calorimetric study of peptide-phospholipid interactions: the glucagon-dimyristoylphosphatidylcholine complex. , 1981, Biochemistry.

[63]  D. Kirschenbaum Molar absorptivity andA1cm1% values for proteins at selected wavelengths of the ultraviolet and visible regions. X , 1975 .

[64]  Y H Chen,et al.  Determination of the helix and beta form of proteins in aqueous solution by circular dichroism. , 1974, Biochemistry.