论文信息 - Free radical chain oxidation and hemolysis of erythrocytes by molecular oxygen and their inhibition by vitamin E.

Free radical chain oxidation and hemolysis of erythrocytes by molecular oxygen and their inhibition by vitamin E.

Erythrocytes of vitamin E-deficient rats and normal rats were oxidized at 37 degrees C by molecular oxygen using a free radical initiator. The erythrocytes were oxidized by a free radical chain mechanism with kinetic chain length considerably larger than 1 and resulted in hemolysis. Vitamin E suppressed both oxidation and hemolysis, but the extent of hemolysis was determined primarily by the extent of oxidation independent of the presence or absence of vitamin E.

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