Insight into Glyproline Peptides’ Activity through the Modulation of the Inflammatory and Neurosignaling Genetic Response Following Cerebral Ischemia–Reperfusion
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S. Limborska | L. Dergunova | I. Filippenkov | V. Stavchansky | A. Denisova | L. Gubsky | N. Myasoedov | L. Andreeva | Julia A. Remizova | Ivan V. Mozgovoy | V. V. Stavchansky
[1] J. Girault,et al. The Non-receptor Tyrosine Kinase Pyk2 in Brain Function and Neurological and Psychiatric Diseases , 2021, Frontiers in Synaptic Neuroscience.
[2] S. Limborska,et al. Antistress Action of Melanocortin Derivatives Associated with Correction of Gene Expression Patterns in the Hippocampus of Male Rats Following Acute Stress , 2021, International journal of molecular sciences.
[3] S. Limborska,et al. Brain Protein Expression Profile Confirms the Protective Effect of the ACTH(4–7)PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia–Reperfusion , 2021, International journal of molecular sciences.
[4] S. Limborska,et al. The Peptide Drug ACTH(4–7)PGP (Semax) Suppresses mRNA Transcripts Encoding Proinflammatory Mediators Induced by Reversible Ischemia of the Rat Brain , 2021, Molecular Biology.
[5] G. Lal,et al. Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity , 2021, Frontiers in Immunology.
[6] S. Limborska,et al. Pharmacotranscriptomics of peptide drugs with neuroprotective properties , 2020, Medicinal research reviews.
[7] S. Limborska,et al. Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia–Reperfusion in Rats , 2020, Genes.
[8] M. Misiura,et al. Proline‐containing peptides—New insight and implications: A Review , 2019, BioFactors.
[9] N. Myasoedov,et al. An integrated approach to study the molecular aspects of regulatory peptides biological mechanism. , 2019, Journal of labelled compounds & radiopharmaceuticals.
[10] D. Fulton,et al. Glial Cell AMPA Receptors in Nervous System Health, Injury and Disease , 2019, International journal of molecular sciences.
[11] S. Limborska,et al. Genome-wide transcriptome analysis using RNA-Seq reveals a large number of differentially expressed genes in a transient MCAO rat model , 2018, BMC Genomics.
[12] R. Snelgrove,et al. The multifaceted roles of the matrikine Pro-Gly-Pro in pulmonary health and disease , 2018, European Respiratory Review.
[13] N. Myasoedov,et al. Synacton and individual activity of synthetic and natural corticotropins , 2017, Journal of molecular recognition : JMR.
[14] S. Limborska,et al. Semax, an analog of ACTH(4−7), regulates expression of immune response genes during ischemic brain injury in rats , 2017, Molecular Genetics and Genomics.
[15] M. Elkind,et al. Inflammatory risk factors, biomarkers and associated therapy in ischaemic stroke , 2016, Nature Reviews Neurology.
[16] Michele Zagnoni,et al. Neuronal networks provide rapid neuroprotection against spreading toxicity , 2016, Scientific Reports.
[17] A. Inozemtsev,et al. Semax prevents learning and memory inhibition by heavy metals , 2016, Doklady Biological Sciences.
[18] David S. Wishart,et al. Heatmapper: web-enabled heat mapping for all , 2016, Nucleic Acids Res..
[19] Hedi Peterson,et al. g:Profiler—a web server for functional interpretation of gene lists (2016 update) , 2016, Nucleic Acids Res..
[20] N. Myasoedov,et al. Mechanisms for glyproline protection in hypercholesterolemia. , 2016, Pathophysiology : the official journal of the International Society for Pathophysiology.
[21] N. Myasoedov,et al. Hypoglycemic and Anticoagulant Effects of Tetrapeptide Pro-Gly-Pro-Leu in Hypercholesterolemia , 2014, Bulletin of Experimental Biology and Medicine.
[22] K. Yamashiro,et al. Phosphorylation enhances recombinant HSP27 neuroprotection against focal cerebral ischemia in mice , 2014, Neuroscience.
[23] N. Myasoedov,et al. Characteristic features of specific binding of pentapeptide HFPGP labeled at the C-terminal proline residue to rat forebrain plasma membranes , 2014, Doklady Biochemistry and Biophysics.
[24] N. Myasoedov,et al. Comparison of pharmacokinetics and metabolism of Pro-Gly-Pro-Leu administered intranasally and intravenously in the blood and brain of rats , 2014, Doklady Biochemistry and Biophysics.
[25] S. Limborska,et al. Tripeptide Pro-Gly-Pro affects rat-brain transcriptome during focal ischemia , 2014, Molecular Biology.
[26] S. Limborska,et al. The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis , 2014, BMC Genomics.
[27] Ziying Wang,et al. NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke. , 2013, Free radical biology & medicine.
[28] N. Myasoedov,et al. Leucine-containing glyprolines (Pro-Gly-Pro-Leu and Leu-Pro-Gly-Pro): Participation in hemostatic reactions in vitro and in vivo in rats with blood coagulation and lipid metabolism disorders , 2013, Doklady Biological Sciences.
[29] N. Myasoedov,et al. Effect of the PRO-GLY-PRO peptide on hemostasis and lipid metabolism in rats with hypercholesterolemia , 2013, Doklady Biological Sciences.
[30] Guohong Li,et al. Role of Inflammation and Its Mediators in Acute Ischemic Stroke , 2013, Journal of Cardiovascular Translational Research.
[31] N. Myasoedov,et al. Proteolysis of simple glyprolines by leucine aminopeptidase and enzymes from nasal mucus, brain membranes, and blood of rats , 2013, Russian Journal of Bioorganic Chemistry.
[32] S. Limborska,et al. Effect of Semax and its C-terminal Fragment Pro-Gly-Pro on the Expression of VEGF Family Genes and their Receptors in Experimental Focal Ischemia of the Rat Brain , 2013, Journal of Molecular Neuroscience.
[33] Wei-Yang Lu,et al. Memory Deficits Induced by Inflammation Are Regulated by α5-Subunit-Containing GABAA Receptors , 2012, Cell reports.
[34] K. Lambertsen,et al. Inflammatory Cytokines in Experimental and Human Stroke , 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[35] A. Hazell,et al. Identification of complexin II in astrocytes: a possible regulator of glutamate release in these cells. , 2011, Biochemical and biophysical research communications.
[36] P. Mcgeer,et al. Astrocytes are GABAergic cells that modulate microglial activity , 2011, Glia.
[37] E. Michaelis,et al. Open Access Research Article Transcriptomic Responses in Mouse Brain Exposed to Chronic Excess of the Neurotransmitter Glutamate , 2022 .
[38] M. Morganti-Kossmann,et al. Role of Chemokines in CNS Health and Pathology: A Focus on the CCL2/CCR2 and CXCL8/CXCR2 Networks , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[39] Martine Uittenbogaard,et al. NeuroD6 genomic signature bridging neuronal differentiation to survival via the molecular chaperone network , 2010, Journal of neuroscience research.
[40] E. Benveniste,et al. SOCS1 and SOCS3 in the control of CNS immunity. , 2009, Trends in immunology.
[41] A. Gaggar,et al. N-α-PGP and PGP, potential biomarkers and therapeutic targets for COPD , 2009, Respiratory research.
[42] Hua Tang,et al. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells. , 2009, American journal of physiology. Cell physiology.
[43] V. Skvortsova,et al. The effect of semax and the C-terminal peptide PGP on expression of growth factor genes and receptors in rats under conditions of experimental cerebral ischemia , 2008, Doklady Biochemistry and Biophysics.
[44] W. Rostène,et al. Chemokines and neuromodulation , 2008, Journal of Neuroimmunology.
[45] N. Myasoedov,et al. Binding of tripeptide Pro-Gly-Pro labeled at the C-terminal proline residue to plasma membranes of the rat forebrain , 2008, Doklady Biological Sciences.
[46] J. Clancy,et al. A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation12 , 2008, The Journal of Immunology.
[47] I. Ashmarin. Glyprolines in regulatory tripeptides , 2007, Neurochemical Journal.
[48] J. Yi,et al. Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage , 2007, Neurochemistry International.
[49] V. Pinelis,et al. Effects of semax and its Pro-Gly-Pro fragment on calcium homeostasis of neurons and their survival under conditions of glutamate toxicity , 2007, Bulletin of Experimental Biology and Medicine.
[50] A. Kraneveld,et al. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation , 2006, Nature Medicine.
[51] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[52] N. Myasoedov,et al. Natural and hybrid ("chimeric") stable regulatory glyproline peptides. , 2005, Pathophysiology : the official journal of the International Society for Pathophysiology.
[53] Elizabeth Schroeder. Activity , 2005, Encyclopedic Dictionary of Archaeology.
[54] P. Shannon,et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.
[55] I. Ashmarin,et al. Glyproline peptide family: review on bioactivity and possible origins. , 2002, Pathophysiology : the official journal of the International Society for Pathophysiology.
[56] G. Horgan,et al. Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR , 2002 .
[57] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[58] O. E. Fadyukova,et al. Novel synthetic analogue of ACTH 4–10 (Semax) but not glycine prevents the enhanced nitric oxide generation in cerebral cortex of rats with incomplete global ischemia , 2001, Brain Research.
[59] I. Ashmarin,et al. The simplest proline-containing peptides PG, GP, PGP, and GPGG: regulatory activity and possible sources of biosynthesis. , 1998, Biochemistry. Biokhimiia.
[60] V. Koshelev,et al. [A nootropic adrenocorticotropin analog 4-10-semax (l5 years experience in its design and study)]. , 1997, Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova.
[61] V. Koshelev,et al. [Increased resistance to hypoxia effected by the neuropeptide preparation SEMAX]. , 1992, Физиология человека.
[62] T. Iglesias,et al. A novel neuroprotection target with distinct regulation in stroke and Alzheimer’s disease , 2017 .
[63] A. Magrì,et al. Semax, an ACTH4-10 peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity. , 2015, Journal of inorganic biochemistry.
[64] L. Lyapina,et al. Functional state of the anticoagulation system after the administration of complexes formed by natural heparin and the regulatory peptides, Pro-Gly, Pro-Gly-Pro, Semax, and tuftsin , 2008 .
[65] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.
[66] N. Myasoedov,et al. Kinetics of semax penetration into the brain and blood of rats after its intranasal administration , 2006, Russian journal of bioorganic chemistry.
[67] M. Pospíšek,et al. Denaturing RNA electrophoresis in TAE agarose gels. , 2005, Analytical biochemistry.
[68] L. Kaczmarek,et al. Ap-1 targets in the brain. , 2004, Frontiers in bioscience : a journal and virtual library.
[69] E. L. Nasonov,et al. [Investigation of mechanisms of neuro-protective effect of semax in acute period of ischemic stroke]. , 1999, Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.
[70] D. de Wied. Neuropeptides in learning and memory processes. , 1997, Behavioural Brain Research.