Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys.
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Johannes Kneer | Yvonne S. Lin | J. Kneer | R. Keck | S. Baughman | Damon I Papac | J. Battersby | Andrew J. S. Jones | Rodney Keck | Yvonne S Lin | Andrew J S Jones | Edward H Chin | Sharon A Baughman | John E Battersby | D. Papac | Edward Chin | A. Jones
[1] K. Anumula. Rapid quantitative determination of sialic acids in glycoproteins by high-performance liquid chromatography with a sensitive fluorescence detection. , 1995, Analytical biochemistry.
[2] F. Maris,et al. Prediction of the in vivo biological activity of human recombinant follicle stimulating hormone using quantitative isoelectric focusing. , 1997, Biologicals : journal of the International Association of Biological Standardization.
[3] A. Morell,et al. The existence of a second route for the transfer of certain glycoproteins from the circulation into the liver. , 1976, Biochemical and biophysical research communications.
[4] I. Sternlieb,et al. Physical and chemical studies on ceruloplasmin. V. Metabolic studies on sialic acid-free ceruloplasmin in vivo. , 1968, The Journal of biological chemistry.
[5] Stacey Ma,et al. Characterization of a complex glycoprotein whose variable metabolic clearance in humans is dependent on terminal N-acetylglucosamine content. , 2008, Biologicals : journal of the International Association of Biological Standardization.
[6] N. Jenkins. Role of physiology in the determination of protein heterogeneity. , 1996, Current opinion in biotechnology.
[7] M. Rogge,et al. Immunomodulation by LFA3TIP, an LFA-3/IgG1 fusion protein: cell line dependent glycosylation effects on pharmacokinetics and pharmacodynamic markers. , 1995, Therapeutic immunology.
[8] A. Jones,et al. Analysis of acidic oligosaccharides and glycopeptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. , 1996, Analytical chemistry.
[9] W. Sly,et al. Inhibition of the rat clearance system for agalacto-orosomucoid by yeast mannans and by mannose. , 1977, Biochemical and biophysical research communications.
[10] Jin‐Kyoo Kim,et al. Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site‐directed mutagenesis , 1994, European journal of immunology.
[11] P. Bjorkman,et al. Fc receptors and their interactions with immunoglobulins. , 1996, Annual review of cell and developmental biology.
[12] A. Jones,et al. Purification and quantitation of tumor necrosis factor receptor immunoadhesin using a combination of immunoaffinity and reversed-phase chromatography. , 1999, Journal of chromatography. B, Biomedical sciences and applications.
[13] G. Gregoriadis,et al. The role of sialic acid in determining the survival of glycoproteins in the circulation. , 1971, The Journal of biological chemistry.
[14] Gerard E. Dallal,et al. PC-SIZE: A Program for Sample-Size Determinations , 1986 .
[15] K. Drickamer. Clearing up glycoprotein hormones , 1991, Cell.
[16] Nathan Sharon,et al. Carbohydrates and glycoconjugates: progress in non-mammalian glycosylation, glycosyltransferases, invertebrate lectins and carbohydrate-carbohydrate interactions. , 2004, Current opinion in structural biology.
[17] S. Wilson,et al. Carbohydrate structures of human tissue plasminogen activator expressed in Chinese hamster ovary cells. , 1989, The Journal of biological chemistry.
[18] G. Ashwell,et al. Carbohydrate-specific receptors of the liver. , 1982, Annual review of biochemistry.
[19] R. Stockert,et al. The asialoglycoprotein receptor: relationships between structure, function, and expression. , 1995, Physiological reviews.
[20] W. Richter,et al. Animal pharmacokinetics of the tumor necrosis factor receptor-immunoglobulin fusion protein lenercept and their extrapolation to humans. , 1999, Drug metabolism and disposition: the biological fate of chemicals.
[21] D A Cumming,et al. Glycosylation of recombinant protein therapeutics: control and functional implications. , 1991, Glycobiology.
[22] P. Capek,et al. Ligand recognition by purified human mannose receptor. , 1992, Archives of biochemistry and biophysics.
[23] J. Briggs,et al. A high-throughput microscale method to release N-linked oligosaccharides from glycoproteins for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis. , 1998, Glycobiology.
[24] A. Morell,et al. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. , 2006, Advances in enzymology and related areas of molecular biology.
[25] D. Goeddel,et al. Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[26] G. Strecker,et al. Studies on glycoconjugates. LXIV. Complete structure of two carbohydrate units of human serotransferrin , 1975, FEBS letters.
[27] Lihua Huang,et al. Impact of variable domain glycosylation on antibody clearance: an LC/MS characterization. , 2006, Analytical biochemistry.
[28] S. Reuveny,et al. Involvement of oligomerization, N-glycosylation and sialylation in the clearance of cholinesterases from the circulation. , 1995, The Biochemical journal.
[29] P. Stahl. The mannose receptor and other macrophage lectins. , 1992 .
[30] P. Stahl,et al. The mannose receptor is a pattern recognition receptor involved in host defense. , 1998, Current opinion in immunology.
[31] P. Umaña,et al. The carbohydrate at FcgammaRIIIa Asn-162. An element required for high affinity binding to non-fucosylated IgG glycoforms. , 2006, The Journal of biological chemistry.
[32] A. Ashkenazi,et al. Immunoadhesins: principles and applications. , 1996, Trends in biotechnology.
[33] H. Bruining,et al. p55 Tumor Necrosis Factor Receptor Fusion Protein in the Treatment of Patients With Severe Sepsis and Septic Shock: A Randomized Controlled Multicenter Trial , 1997 .
[34] S L Morrison,et al. Effect of glycosylation on antibody function: implications for genetic engineering. , 1997, Trends in biotechnology.
[35] Matrix-assisted laser desorption/ionization mass spectrometry of carbohydrates and glycoconjugates , 2003 .
[36] A. Morell,et al. Physical and chemical studies on ceruloplasmin. IX. The role of galactosyl residues in the clearance of ceruloplasmin from the circulation. , 1970, The Journal of biological chemistry.
[37] Mark J. Miller,et al. Evidence for receptor-mediated binding of glycoproteins, glycoconjugates, and lysosomal glycosidases by alveolar macrophages. , 1978, Proceedings of the National Academy of Sciences of the United States of America.
[38] S L Morrison,et al. Effect of altered CH2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1 , 1994, The Journal of experimental medicine.
[39] K. Rice,et al. Oligosaccharide valency and conformation in determining binding to the asialoglycoprotein receptor of rat hepatocytes. , 1993, Advances in enzymology and related areas of molecular biology.
[40] D. Banner,et al. Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation , 1993, Cell.