论文信息 - CMOS chips for bio molecule sensing purposes

CMOS chips for bio molecule sensing purposes

A topical review is given concerning CMOS-based DNA microarrays. Considering the entire application chain, functionalization techniques, required CMOS process extensions and consequences, and a number of readout techniques are discussed. Related circuit design issues and CMOS implementations are highlighted as well.

R. Thewes | R. Thewes

[1] Wei Wang,et al. Antigen detection using microelectrode array microchips , 2001 .

[2] M. J. Heller,et al. An active microelectronics device for multiplex DNA analysis , 1996 .

[3] M. Morley,et al. Making and reading microarrays , 1999, Nature Genetics.

[4] R. Hintsche,et al. Microbiosensors using electrodes made in Si-technology. , 1997, EXS.

[5] Mark Schena,et al. DNA microarrays : a practical approach , 1999 .

[6] R. Thewes,et al. A fully electronic DNA sensor with 128 positions and in-pixel A/D conversion , 2004, IEEE Journal of Solid-State Circuits.

[7] S. P. Fodor,et al. Multiplexed biochemical assays with biological chips , 1993, Nature.

[8] Allen J. Bard,et al. Digital Simulation of the Measured Electrochemical Response of Reversible Redox Couples at Microelectrode Arrays: Consequences Arising from Closely Spaced Ultramicroelectrodes , 1986 .