Carbon dioxide laser treatment for lipoid proteinosis (Urbach–Wiethe syndrome) involving the eyelids

Editor,—Urbach–Wiethe syndrome is a rare autosomal recessive disorder associated with hyaline-like deposits in the skin and pharyngolaryngeal mucous membranes causing dysphonia and hoarseness.1 2 Ocular manifestations include deposits along the free edges of the eyelids (moniliform blepharosis), conjunctiva, cornea, trabeculum, and Bruch’s membrane.3 4 We used carbon dioxide laser as a new surgical method to alleviate the papular lesion from the eyelids. ### CASE REPORT A 21-year-old Bedouin woman was referred to our centre for ophthalmic examination. Although a negative family history of Urbach–Wiethe syndrome was known, the patient and her brother suffered from this disorder. The patient complained of yellowish papular lesions that occupied the entire lid margin of the upper two lids. She suffered from hoarseness caused by papules situated on the vocal cord and hyperkeratotic …