论文信息 - Cooperative Behavior of Molecular Motors

Cooperative Behavior of Molecular Motors

All directed movements of living organisms are based on molecular machines which perform mechanical work on the nanometer scale. This article reviews recent work on molecular motors which bind to cytoskeletal filaments and walk along these filaments in a directed fashion; for a review, see [1]. Several systems and processes arising from the interplay of these motors and filaments will be discussed: dilute systems in which one can study the movement of single motor molecules along ordered [2] and disordered [3] filament tracks; ‘motor walks’ consisting of many diusional encounters between motor and filament [4]; transport of cargo particles by several motors that can cover macroscopic distances and may exhibit bi-directional movement [5]; active diusion along substrate surfaces with immobilized filaments [6]; and systems with many interacting motors that exhibit trac jams, self-organized density and

Reinhard Lipowsky | R. Lipowsky

[1] R. Lipowsky,et al. Universal aspects of the chemomechanical coupling for molecular motors. , 2000, Physical review letters.

[2] T. Nieuwenhuizen,et al. UvA-DARE ( Digital Academic Repository ) Random walks of cytoskeletal motors in open and closed compartments , 2001 .

[3] Reinhard Lipowsky,et al. Phase transitions in systems with two species of molecular motors , 2004, cond-mat/0402195.

[4] Reinhard Lipowsky,et al. Active diffusion of motor particles. , 2005, Physical review letters.

[5] Reinhard Lipowsky,et al. Self-organized density patterns of molecular motors in arrays of cytoskeletal filaments. , 2005, Biophysical journal.

[6] R. Lipowsky,et al. Driven ratchets with disordered tracks , 1997 .

[7] Reinhard Lipowsky,et al. 'Life is motion': multiscale motility of molecular motors , 2005 .

[8] R. Lipowsky,et al. Cooperative cargo transport by several molecular motors. , 2005, Proceedings of the National Academy of Sciences of the United States of America.