Novel ferrocene-pyrazolo[1,5-a]pyrimidine hybrids: A facile environment-friendly regioselective synthesis, structure elucidation, and their antioxidant, antibacterial, and anti-biofilm activities

[1]  N. Al-Dhabi,et al.  Synthesis, X-ray structural determination and biological evaluation of novel ferrocene grafted spiroquinoxalinopyrrolidine , 2021, Journal of Molecular Structure.

[2]  A. Kilic,et al.  Synthesis and electrochemical investigation of chiral amine bis(phenolate)-boron complexes: In vitro antibacterial activity screening of boron compounds , 2020, Inorganica Chimica Acta.

[3]  L. I. Singha,et al.  Ultrasound assisted synthesis of pyrazolo[1,5-a]pyrimidine-antipyrine hybrids and their anti-inflammatory and anti-cancer activities , 2020 .

[4]  Bo Zhang,et al.  Artemisinin‐derived dimers as potential anticancer agents: Current developments, action mechanisms, and structure–activity relationships , 2019, Archiv der Pharmazie.

[5]  I. Bratsos,et al.  Chemistry and reactivity of ruthenium(II) complexes: DNA/protein binding mode and anticancer activity are related to the complex structure , 2019, Coordination Chemistry Reviews.

[6]  A. Mittermaier,et al.  Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. , 2019, European journal of medicinal chemistry.

[7]  L. Wiesner,et al.  Ferroquine-derived polyamines that target resistant Plasmodium falciparum. , 2019, European journal of medicinal chemistry.

[8]  J. Correia,et al.  Ferrocene derivatives as anti-infective agents , 2019, Coordination Chemistry Reviews.

[9]  B. Aderibigbe,et al.  Ferrocene-Based Compounds with Antimalaria/Anticancer Activity , 2019, Molecules.

[10]  Zhi Xu,et al.  Tetrazole hybrids with potential anticancer activity. , 2019, European journal of medicinal chemistry.

[11]  Mi Yan,et al.  Indole: A privileged scaffold for the design of anti-cancer agents. , 2019, European journal of medicinal chemistry.

[12]  S. P.,et al.  Hydrothermal assisted Eichhornia crassipes mediated synthesis of magnetite nanoparticles (E-Fe3O4) and its antibiofilm activity , 2019, Materials Research Express.

[13]  H. Aisa,et al.  1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview , 2019, Bioorganic & Medicinal Chemistry.

[14]  F. Fasina,et al.  Antibacterial and antibiofilm activity of acetone leaf extracts of nine under-investigated south African Eugenia and Syzygium (Myrtaceae) species and their selectivity indices , 2019, BMC Complementary and Alternative Medicine.

[15]  R. Prakasham,et al.  Synthesis, characterization and antimicrobial evaluation of ferrocene–oxime ether benzyl 1H-1,2,3-triazole hybrids , 2019, New Journal of Chemistry.

[16]  Lei Tao,et al.  Ferrocene-Containing Polymer via the Biginelli Reaction for In Vivo Treatment of Oxidative Stress Damage. , 2019, ACS macro letters.

[17]  Sasmita Mishra,et al.  Synthesis of Ferrocene Tethered Heteroaromatic Compounds Using Solid Supported Reaction Method, their Cytotoxic Evaluation and Fluorescence Behavior. , 2019, ChemistrySelect.

[18]  K. Tennekoon,et al.  Emerging role of histone deacetylase inhibitors as anti-breast-cancer agents. , 2019, Drug discovery today.

[19]  A. Guirado,et al.  Therapeutic potential of pteridine derivatives: A comprehensive review , 2018, Medicinal research reviews.

[20]  Saeed Emami,et al.  Indole in the target-based design of anticancer agents: A versatile scaffold with diverse mechanisms. , 2018, European journal of medicinal chemistry.

[21]  Karunakaran A Kalesh,et al.  Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action , 2017, Medicinal research reviews.

[22]  L. I. Singha,et al.  Design, synthesis, structure elucidation, and biological activities of 3-(substituted amino)-1-(pyridin-4-yl)propenones and 5-isonicotinoyl-1,2,3,4-tetrahydropyrimidine–adamantane hybrids , 2017, Monatshefte für Chemie - Chemical Monthly.

[23]  C. Xing,et al.  Chalcone: A Privileged Structure in Medicinal Chemistry. , 2017, Chemical reviews.

[24]  S. Cherukupalli,et al.  An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold. , 2017, European journal of medicinal chemistry.

[25]  T. Egan,et al.  Mono- and multimeric ferrocene congeners of quinoline-based polyamines as potential antiparasitics. , 2016, Dalton transactions.

[26]  P. Sujitha,et al.  Ferrocenyl chalcogeno (sugar) triazole conjugates: Synthesis, characterization and anticancer properties , 2016 .

[27]  P. Dunlop,et al.  Resazurin-based 96-well plate microdilution method for the determination of minimum inhibitory concentration of biosurfactants , 2016, Biotechnology Letters.

[28]  J. N. Vishwakarma,et al.  Catalyst-free multicomponent synthesis of novel adamantyl-containing tetrahydropyrimidine carboxylates , 2016, Molecular Diversity.

[29]  L. I. Singha,et al.  A facile, regioselective synthesis of pyrazolo[1, 5-a]pyrimidine analogs in the presence of KHSO4 in aqueous media assisted by ultrasound and their anti-inflammatory and anti-cancer activities , 2016, Monatshefte für Chemie - Chemical Monthly.

[30]  G. Bérubé An overview of molecular hybrids in drug discovery , 2016, Expert opinion on drug discovery.

[31]  J. Padrón,et al.  Catalytically Generated Ferrocene-Containing Guanidines as Efficient Precursors for New Redox-Active Heterometallic Platinum(II) Complexes with Anticancer Activity , 2015 .

[32]  K. Chibale,et al.  Ferrocene-pyrimidine conjugates: Synthesis, electrochemistry, physicochemical properties and antiplasmodial activities. , 2015, European journal of medicinal chemistry.

[33]  L. I. Singha,et al.  Novel tetrahydropyrimidine–adamantane hybrids as anti-inflammatory agents: synthesis, structure and biological evaluation , 2015, Medicinal Chemistry Research.

[34]  Richard J. Gildea,et al.  The anatomy of a comprehensive constrained, restrained refinement program for the modern computing environment – Olex2 dissected , 2015, Acta crystallographica. Section A, Foundations and advances.

[35]  G. Sheldrick SHELXT – Integrated space-group and crystal-structure determination , 2015, Acta crystallographica. Section A, Foundations and advances.

[36]  N. Jux,et al.  Effect of ferrocene-substituted porphyrin RL-91 on Candida albicans biofilm formation. , 2014, Bioorganic & medicinal chemistry letters.

[37]  Vipan Kumar,et al.  Azide-alkyne cycloaddition en route towards 1H-1,2,3-triazole-tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone conjugates: synthesis and in vitro anti-tubercular evaluation. , 2013, Dalton transactions.

[38]  Vipan Kumar,et al.  Synthesis and in vitro anti-tubercular evaluation of 1,2,3-triazole tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone chimeric scaffolds. , 2012, Dalton transactions.

[39]  P. Juvekar,et al.  Antioxidant activity and free radical-scavenging potential of Pithecellobium dulce Benth seed extracts , 2014 .

[40]  Zdenko Časar,et al.  Iridium-catalyzed chemoselective and enantioselective hydrogenation of (1-chloro-1-alkenyl) boronic esters. , 2012, Angewandte Chemie.

[41]  J. Matta,et al.  Vectorized ferrocenes with estrogens and vitamin D2: synthesis, cytotoxic activity and docking studies. , 2011, Dalton transactions.

[42]  O. Amaeze,et al.  Evaluation of Antioxidant Activity of Tetracarpidium conophorum (Müll. Arg) Hutch & Dalziel Leaves , 2011, Oxidative medicine and cellular longevity.

[43]  G. Déléris,et al.  New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity--Part II. , 2011, European journal of medicinal chemistry.

[44]  R. Shukla,et al.  Development of a peptide-drug conjugate for prostate cancer therapy. , 2011, Molecular pharmaceutics.

[45]  J. Havlíček,et al.  Synthetic studies connected with the preparation of N-〔3-(3-cyanopyrazolo〔1,5-a〕pyrimidin-5-yl)phenyl〕-N-ethylacetamide, a zaleplon regioisomer , 2010 .

[46]  Aurobinda Panda,et al.  THE EVALUATION OF NITRIC OXIDE SCAVENGING ACTIVITY OF ACALYPHA INDICA LINN ROOT , 2009 .

[47]  Richard J. Gildea,et al.  OLEX2: a complete structure solution, refinement and analysis program , 2009 .

[48]  Chun-Hsien Yu,et al.  Evaluation of NO-suppressing activity of several Mediterranean culinary spices. , 2007, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[49]  M. Moyá,et al.  Radical scavenging ability of polyphenolic compounds towards DPPH free radical. , 2007, Talanta.

[50]  Carlton A Taft,et al.  Rational design of novel diketoacid-containing ferrocene inhibitors of HIV-1 integrase. , 2005, Bioorganic chemistry.

[51]  K. Shimada,et al.  Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion , 1992 .

[52]  Hyoung S. Lee Antioxidative activity of browning reaction products isolated from storage-aged orange juice , 1992 .

[53]  J. Spencer,et al.  Ferrocenes in medicinal chemistry; a personal perspective , 2020 .

[54]  F. Gao,et al.  Current scenario of ferrocene-containing hybrids for antimalarial activity. , 2019, European journal of medicinal chemistry.

[55]  Ting Wang,et al.  Research advances in the use of histone deacetylase inhibitors for epigenetic targeting of cancer. , 2019, Current topics in medicinal chemistry.

[56]  J. N. Vishwakarma,et al.  Ultrasound assisted synthesis of 1-amino-3-ferrocenyl-3-oxoprop-1-enes , 2018 .

[57]  Ranfeng Sun,et al.  Design, synthesis and fungicidal activity studies of 3-ferrocenyl-N-acryloylmorpholine , 2018 .

[58]  A. Khelef,et al.  In vitro assays of the antioxidant activities of ferrocene derivatives bearingamine, amide or hydrazine groups , 2015 .

[59]  P. Sujitha,et al.  (4-Ferrocenylphenyl)propargyl ether derived carbohydrate triazoles: influence of a hydrophobic linker on the electrochemical and cytotoxic properties , 2014 .

[60]  R. Shah,et al.  Inhibitory activity of yarrow essential oil on Listeria planktonic cells and biofilms , 2013 .

[61]  Kazuko. Shimada,et al.  ANTIOXIDATIVE PROPERTIES OF XANTHONE ON THE AUTO OXIDATION OF SOYBEAN IN CYLCODEXTRIN EMULSION , 1992 .