Phosphene Mapping Techniques for Visual Prostheses

Mapping of the visual world onto the visual system occurs in a highly ordered manner, yet with substantial interindividual variability. Since the retinal map of the scene at the photoreceptor level is fully determined by the optical projection of the eye, it is likely that a proximal map generated by a retinal prosthesis closely adheres to the same geometric projection. Once the nerve signals enter the optic nerve, this orderly map is redistributed, and while maps at more proximal levels still follow general rules, special mapping techniques in individual LGN or cortical prosthesis recipients will be required to allow reconstruction of spatial ­relationships in the outside world by means of a disorderly array of phosphenes.

[1]  Toshiaki Taoka,et al.  Retinotopy with coordinates of lateral occipital cortex in humans. , 2004, Journal of neurosurgery.

[2]  E Marg,et al.  Phosphenes Induced by Magnetic Stimulation Over the Occipital Brain: Description and Probable Site of Stimulation , 1994, Optometry and vision science : official publication of the American Academy of Optometry.

[3]  D N Rushton,et al.  A method for plotting the optimum positions of an array of cortical electrical phosphenes. , 1978, Biometrics.

[4]  W. H. Dobelle Artificial vision for the blind by connecting a television camera to the visual cortex. , 2000, ASAIO journal.

[5]  N Drasdo,et al.  Non-linear projection of the retinal image in a wide-angle schematic eye. , 1974, The British journal of ophthalmology.

[6]  C. Veraart,et al.  Creating a meaningful visual perception in blind volunteers by optic nerve stimulation , 2005, Journal of neural engineering.

[7]  Gislin Dagnelie,et al.  Phosphene mapping strategies for cortical visual prosthesis recipients , 2010 .

[8]  G. Brindley,et al.  The sensations produced by electrical stimulation of the visual cortex , 1968, The Journal of physiology.

[9]  Gislin Dagnelie,et al.  Phosphene Mapping Procedures for Prosthetic Vision , 1999 .

[10]  M. Martinez,et al.  Mapping of the human visual cortex using image-guided transcranial magnetic stimulation. , 2002, Brain research. Brain research protocols.

[11]  C. Veraart,et al.  Position, size and luminosity of phosphenes generated by direct optic nerve stimulation , 2003, Vision Research.

[12]  C M Epstein,et al.  Magnetic stimulation of visual cortex: factors influencing the perception of phosphenes. , 1998, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[13]  W H Dobelle,et al.  Mapping the representation of the visual field by electrical stimulation of human visual cortex. , 1979, American journal of ophthalmology.

[14]  Donald K. Eddington,et al.  A Computer-Based Brain Stimulation System to Investigate Sensory Prostheses for the Blind and Deaf , 1976, IEEE Transactions on Biomedical Engineering.

[15]  G. Holmes DISTURBANCES OF VISION BY CEREBRAL LESIONS , 1918, The British journal of ophthalmology.

[16]  Kaijie Wu,et al.  Tactile Based Phosphene Positioning System for Visual Prosthesis , 2007 .

[17]  J. Mortimer,et al.  Visual sensations produced by optic nerve stimulation using an implanted self-sizing spiral cuff electrode , 1998, Brain Research.

[18]  Qiushi Ren,et al.  Dispersion and accuracy of simulated phosphene positioning using tactile board. , 2009, Artificial organs.

[19]  W. Dobelle,et al.  Phosphenes produced by electrical stimulation of human occipital cortex, and their application to the development of a prosthesis for the blind , 1974, The Journal of physiology.

[20]  Bernhard A. Sabel,et al.  Changes in visual cortex excitability in blind subjects as demonstrated by transcranial magnetic stimulation. , 2002, Brain : a journal of neurology.

[21]  M. Alexander,et al.  Principles of Neural Science , 1981 .

[22]  C. Kufta,et al.  Feasibility of a visual prosthesis for the blind based on intracortical microstimulation of the visual cortex. , 1996, Brain : a journal of neurology.

[23]  A. Cowey,et al.  Magnetically induced phosphenes in sighted, blind and blindsighted observers , 2000, Neuroreport.

[24]  G. Loeb,et al.  Visual sensations produced by intracortical microstimulation of the human occipital cortex , 1990, Medical and Biological Engineering and Computing.

[25]  Gislin Dagnelie,et al.  Visual perception in a blind subject with a chronic microelectronic retinal prosthesis , 2003, Vision Research.

[26]  Benoît Gérard,et al.  Pattern recognition with the optic nerve visual prosthesis. , 2003, Artificial organs.

[27]  J. Kruskal Nonmetric multidimensional scaling: A numerical method , 1964 .

[28]  A. Milam,et al.  Histopathology of the human retina in retinitis pigmentosa. , 1998, Progress in retinal and eye research.

[29]  J. Weiland,et al.  Pattern electrical stimulation of the human retina , 1999, Vision Research.

[30]  Enrica Strettoi,et al.  Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: A morphological and ERG study , 2007, The Journal of comparative neurology.

[31]  R. H. Propst,et al.  Visual perception elicited by electrical stimulation of retina in blind humans. , 1996, Archives of ophthalmology.