HSPB1 as a Novel Regulator of Ferroptotic Cancer Cell Death

[1]  A. Walch,et al.  Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice , 2014, Nature Cell Biology.

[2]  D. Green,et al.  Synchronized renal tubular cell death involves ferroptosis , 2014, Proceedings of the National Academy of Sciences.

[3]  D Andrews,et al.  Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 , 2014, Cell Death and Differentiation.

[4]  Haichao Wang,et al.  PKM2 Regulates the Warburg Effect and Promotes HMGB1 Release in Sepsis , 2014, Nature Communications.

[5]  Matthew E. Welsch,et al.  Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis , 2014, eLife.

[6]  D. Green,et al.  Die another way – non-apoptotic mechanisms of cell death , 2014, Journal of Cell Science.

[7]  B. Stockwell,et al.  Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models , 2014, Journal of the American Chemical Society.

[8]  R. Ramanathan,et al.  Covalent binding of 4-hydroxy-2-nonenal to lactate dehydrogenase decreases NADH formation and metmyoglobin reducing activity. , 2014, Journal of agricultural and food chemistry.

[9]  P. Vandenabeele,et al.  Regulated necrosis: the expanding network of non-apoptotic cell death pathways , 2014, Nature Reviews Molecular Cell Biology.

[10]  Matthew E. Welsch,et al.  Regulation of Ferroptotic Cancer Cell Death by GPX4 , 2014, Cell.

[11]  F. Torti,et al.  Iron and cancer: more ore to be mined , 2013, Nature Reviews Cancer.

[12]  M. R. Lamprecht,et al.  Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death , 2012, Cell.

[13]  N. Wilson,et al.  Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target , 2012, Fibrogenesis & tissue repair.

[14]  Simon C Watkins,et al.  p53/HMGB1 complexes regulate autophagy and apoptosis. , 2012, Cancer research.

[15]  H. Steller,et al.  Programmed Cell Death in Animal Development and Disease , 2011, Cell.

[16]  R A Knight,et al.  Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 , 2011, Cell Death and Differentiation.

[17]  G. Kroemer,et al.  High-mobility group box 1 is essential for mitochondrial quality control. , 2011, Cell metabolism.

[18]  I. Benjamin,et al.  Involvement of Reductive Stress in the Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Heat Shock Protein 27 , 2010, Hypertension.

[19]  Osamu Hori,et al.  Cellular Stress Responses: Cell Survival and Cell Death , 2010, International journal of cell biology.

[20]  B. Stockwell,et al.  Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. , 2008, Chemistry & biology.

[21]  B. Stockwell,et al.  RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels , 2007, Nature.

[22]  R. Bergan,et al.  MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer , 2006, Oncogene.

[23]  D. Han,et al.  Blocking Tumor Cell Migration and Invasion with Biphenyl Isoxazole Derivative KRIBB3, a Synthetic Molecule That Inhibits Hsp27 Phosphorylation* , 2005, Journal of Biological Chemistry.

[24]  Su-Jae Lee,et al.  HSP25 Inhibits Protein Kinase Cδ-mediated Cell Death through Direct Interaction* , 2005, Journal of Biological Chemistry.

[25]  D. Tang,et al.  HEAT SHOCK RESPONSE INHIBITS RELEASE OF HIGH MOBILITY GROUP BOX 1 PROTEIN INDUCED BY ENDOTOXIN IN MURINE MACROPHAGES , 2005, Shock.

[26]  S. Chaufour,et al.  Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels. , 2005, Antioxidants & redox signaling.

[27]  John C Reed,et al.  Heat-shock proteins as regulators of apoptosis , 2003, Oncogene.

[28]  J. Carver,et al.  Small Heat‐shock Proteins and Clusterin: Intra‐ and Extracellular Molecular Chaperones with a Common Mechanism of Action and Function? , 2003, IUBMB life.

[29]  William C Hahn,et al.  Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. , 2003, Cancer cell.

[30]  Jacques Landry,et al.  p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells , 1997, Oncogene.

[31]  J. Landry,et al.  Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27. , 1997, Journal of cell science.

[32]  J. Landry,et al.  HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress. , 1996, Cancer research.

[33]  J. Landry,et al.  Modulation of actin microfilament dynamics and fluid phase pinocytosis by phosphorylation of heat shock protein 27. , 1993, The Journal of biological chemistry.

[34]  S. Fuqua,et al.  The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines. , 1993, Cancer research.

[35]  M. Gaestel,et al.  Small heat shock proteins are molecular chaperones. , 1993, The Journal of biological chemistry.

[36]  B. Stockwell,et al.  The role of iron and reactive oxygen species in cell death. , 2014, Nature Chemical Biology.

[37]  D. Tang,et al.  HMGB1 promotes drug resistance in osteosarcoma. , 2012, Cancer research.

[38]  N. Wilson,et al.  Heat shock protein 27 ( HSP 27 ) : biomarker of disease and therapeutic target , 2012 .

[39]  Shiro Suetsugu,et al.  The WASP–WAVE protein network: connecting the membrane to the cytoskeleton , 2007, Nature Reviews Molecular Cell Biology.

[40]  Z. Qian,et al.  Heat shock protein 27 downregulates the transferrin receptor 1-mediated iron uptake. , 2006, The international journal of biochemistry & cell biology.

[41]  Su-Jae Lee,et al.  HSP25 inhibits protein kinase C delta-mediated cell death through direct interaction. , 2005, The Journal of biological chemistry.

[42]  William Arbuthnot Sir Lane,et al.  Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress , 2005 .

[43]  Carl Wu,et al.  Heat shock transcription factors: structure and regulation. , 1995, Annual review of cell and developmental biology.

[44]  C. Georgopoulos,et al.  Role of the major heat shock proteins as molecular chaperones. , 1993, Annual review of cell biology.

[45]  Matthias W. Hentze,et al.  Two to Tango: Regulation of Mammalian Iron Metabolism , 2010, Cell.