Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability.
暂无分享,去创建一个
[1] P. Mandelstam,et al. A study of the mechanism of intestinal absorption of benzo(a)pyrene. , 1971, Biochimica et biophysica acta.
[2] Eder Ha. The effect of diet on the transport of probucol in monkeys. , 1982 .
[3] M. Lemaire,et al. Intestinal lymphatic absorption of cyclosporin A following oral administration in an olive oil solution in rats. , 1983, Biopharmaceutics & drug disposition.
[4] K J Palin,et al. The effect of different oils on the absorption of probucol in the rat , 1984, The Journal of pharmacy and pharmacology.
[5] V. Stella,et al. Lymphatic appearance of DDT in thoracic or mesenteric lymph duct cannulated rats , 1985 .
[6] V. Stella,et al. Estimating the maximal potential for intestinal lymphatic transport of lipophilic drug molecules , 1986 .
[7] J. Kvetina,et al. The pharmacokinetics of intraduodenally administered diazepam in rats as influenced by composition of the central lymph. , 1989, Physiologia Bohemoslovaca.
[8] J. Kvetina,et al. Influence of the composition of rat central lymph on the pharmacokinetics (the steady state during infusion, bioavailability, absorption) of diazepam, studied in the blood and lymph. , 1990, Physiologia Bohemoslovaca.
[9] R. Sawchuk,et al. Effect of co‐administration of intralipidTM on the pharmacokinetics of cyclosporine in the rabbit , 1991, Biopharmaceutics & drug disposition.
[10] V. Stella,et al. Factors affecting the lymphatic transport of penclomedine (NSC-338720), a lipophilic cytotoxic drug: Comparison to DDT and hexachlorobenzene , 1992 .
[11] N el Tayar,et al. Solvent-dependent conformation and hydrogen-bonding capacity of cyclosporin A: evidence from partition coefficients and molecular dynamics simulations. , 1993, Journal of medicinal chemistry.
[12] J. Barré,et al. Effects of Plasma Lipid Levels on Blood Distribution and Pharmacokinetics of Cyclosporin A , 1993, Therapeutic drug monitoring.
[13] K. Yamamoto,et al. Effects of dietary fat levels on the absorption and tissue accumulation of probucol in the rat. , 1994, Arzneimittel-Forschung.
[14] E. Anggard,et al. Measurement of plasma probucol levels by high-performance liquid chromatography. , 1994, Journal of chromatography. B, Biomedical applications.
[15] A. Hamsten,et al. Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE. , 1994, Journal of lipid research.
[16] D. Hauss,et al. Targeted lymphatic transport and modified systemic distribution of CI-976, a lipophilic lipid-regulator drug, via a formulation approach , 1994 .
[17] G. Lopez-Berestein,et al. Modification of Amphotericin B's Therapeutic Index by Increasing Its Association with Serum High‐Density Lipoproteins a , 1994, Annals of the New York Academy of Sciences.
[18] D. B. Gomis,et al. Simultaneous determination of vitamins D3, E and K1 and retinyl palmitate in cattle plasma by liquid chromatography with a narrow-bore column. , 1994, Journal of chromatography. B, Biomedical applications.
[19] C. Porter,et al. A simplified liquid chromatography assay for the quantitation of halofantrine and desbutylhalofantrine in plasma and identification of a degradation product of desbutylhalofantrine formed under alkaline conditions. , 1995, Journal of pharmaceutical and biomedical analysis.
[20] M. Ueno,et al. Mechanism of promotion of lymphatic drug absorption by milk fat globule membrane , 1995 .
[21] C. Porter,et al. Lymphatic transport of halofantrine in the triple-cannulated anesthetized rat model: effect of lipid vehicle dispersion. , 1996, Journal of pharmaceutical sciences.
[22] C. Porter,et al. Lipophilic prodrugs designed for intestinal lymphatic transport , 1996 .
[23] A. Hamsten,et al. Apolipoprotein B-48. , 1996, Methods in enzymology.
[24] A. P. Arzamastsev,et al. [Determination of bifonazole using HPLC in pharmacokinetic studies]. , 1996, Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic].
[25] S. Davis,et al. Intestinal lymphatic transport of three retinoids in the rat after oral administration: Effect of lipophilicity and lipid vehicle , 1996 .
[26] R. Krauss,et al. Intermediate-density lipoproteins and progression of carotid arterial wall intima-media thickness. , 1997, Circulation.
[27] G. Edwards,et al. Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state. , 1998, Journal of pharmaceutical sciences.
[28] L. Notarianni,et al. Rapid and simple chromatographic method for the determination of diazepam and its major metabolites in human plasma and urine. , 1998, Journal of chromatography. B, Biomedical sciences and applications.
[29] S. Noh,et al. Marginal Zinc Deficiency Lowers the Lymphatic Absorption of α-Tocopherol in Rats , 1998 .
[30] K. Wasan,et al. Role of plasma lipoproteins in modifying the biological activity of hydrophobic drugs. , 1998, Journal of pharmaceutical sciences.
[31] C. Porter,et al. Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of core apolar lipoprotein lipid. , 1999, Journal of pharmaceutical sciences.
[32] J. Fialip,et al. High-performance liquid chromatographic determination of paclitaxel in rat serum: application to a toxicokinetic study. , 1999, Journal of chromatography. B, Biomedical sciences and applications.
[33] M. Hussain,et al. Assembly and Secretion of Chylomicrons by Differentiated Caco-2 Cells , 1999, The Journal of Biological Chemistry.
[34] C. Porter,et al. Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats. , 2000, Journal of pharmaceutical sciences.
[35] M. Hussain. A proposed model for the assembly of chylomicrons. , 2000, Atherosclerosis.
[36] P. Tso,et al. An examination of the factors affecting intestinal lymphatic transport of dietary lipids. , 2001, Advanced drug delivery reviews.
[37] G. Edwards,et al. Animal models for the study of intestinal lymphatic drug transport. , 2001, Advanced drug delivery reviews.
[38] G. Gaedicke,et al. Synthesis and preclinical characterization of a paclitaxel prodrug with improved antitumor activity and water solubility. , 2001, Bioconjugate chemistry.
[39] C. Porter,et al. Intestinal lymphatic drug transport: an update. , 2001, Advanced drug delivery reviews.
[40] C. O’Driscoll. Lipid-based formulations for intestinal lymphatic delivery. , 2002, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[41] K. Wasan. The Role of Lymphatic Transport in Enhancing Oral Protein and Peptide Drug Delivery , 2002, Drug development and industrial pharmacy.
[42] M. Khan,et al. Development of a HPLC method for the determination of cyclosporin-A in rat blood and plasma using naproxen as an internal standard. , 2003, Journal of pharmaceutical and biomedical analysis.
[43] H. Yamada,et al. A Quantitative Concept of the Mechanism of Intestinal Lymphatic Transfer of Lipophilic Molecules , 1994, Pharmaceutical Research.
[44] Ben J. Boyd,et al. Drug Solubilization Behavior During in Vitro Digestion of Simple Triglyceride Lipid Solution Formulations , 2004, Pharmaceutical Research.
[45] E. Donnachie,et al. Differences in Lipoprotein Lipid Concentration and Composition Modify the Plasma Distribution of Cyclosporine , 1997, Pharmaceutical Research.
[46] René Holm,et al. Successful in silico predicting of intestinal lymphatic transfer. , 2004, International journal of pharmaceutics.
[47] C. Porter,et al. Evaluation of the impact of altered lipoprotein binding conditions on halofantrine induced QTc interval prolongation in an anaesthetized rabbit model , 2004, The Journal of pharmacy and pharmacology.
[48] A. Hoffman,et al. Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs. , 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.