Mucoepidermoid Carcinoma in Warthin Tumor of the Parotis in Childhood: A Case Report and Review of the Literature.

Mucoepidermoid carcinoma arising in Warthin tumor of the parotid gland is an extremely rare entity. This is so far described only in the adult age group, and only one patient has been reported in the pediatric age group until today. Herein, we describe our patient and review the literature. This was a case of a 9-year-old girl admitted with a painless swelling in the left side of her face for at least 2 weeks. Histopathologic examination of total parotidectomy specimens revealed mucoepidermoid carcinoma arising in the Warthin tumor. This case is the youngest patient reported to date.

[1]  K. Thway,et al.  Warthin Tumor–Like Mucoepidermoid Carcinoma , 2018, International journal of surgical pathology.

[2]  L. Licitra,et al.  Systemic therapy in metastatic salivary gland carcinomas: A pathology-driven paradigm? , 2017, Oral oncology.

[3]  M. Elmaleh,et al.  Pediatric salivary gland carcinomas: Diagnostic and therapeutic management , 2017, The Laryngoscope.

[4]  Chunkai Yu,et al.  Mucoepidermoid carcinoma arising in Warthin’s tumor of the parotid gland: Clinicopathological characteristics and immunophenotypes , 2016, Scientific Reports.

[5]  M. Chintagumpala,et al.  Mucoepidermoid Carcinoma in Children: A Single Institutional Experience , 2016, Pediatric blood & cancer.

[6]  T. Vece,et al.  Childhood and adolescent tracheobronchial mucoepidermoid carcinoma (MEC): a case-series and review of the literature , 2016, Pediatric Surgery International.

[7]  W. Smółka,et al.  Mucoepidermoid carcinoma in Warthin tumor of the parotid gland , 2015, Archives of medical science : AMS.

[8]  E. Miles,et al.  Postoperative Radiation Therapy for Parotid Mucoepidermoid Carcinoma , 2014, Case reports in oncological medicine.

[9]  M. Mohapatra,et al.  Low grade mucoepidermoid carcinoma in a setting of Warthin's tumor. , 2012, Indian journal of pathology & microbiology.

[10]  R. Weber,et al.  CRTC1/MAML2 fusion transcript in Warthin's tumor and mucoepidermoid carcinoma: Evidence for a common genetic association , 2008, Genes, chromosomes & cancer.

[11]  K. Mardi,et al.  Mucoepidermoid carcinoma arising in Warthin's tumor: a case report. , 2007, Indian journal of pathology & microbiology.

[12]  G. Tonon,et al.  A study of MECT1-MAML2 in mucoepidermoid carcinoma and Warthin's tumor of salivary glands. , 2004, The Journal of molecular diagnostics : JMD.

[13]  A. Mizuno,et al.  Mucoepidermoid carcinoma arising in Warthin's tumor of the parotid gland , 2002, Pathology international.

[14]  M. Lingen,et al.  Synchronous benign and malignant salivary gland tumors in ipsilateral glands: A report of two cases and a review of literature , 2002, Head & neck.

[15]  L. Medeiros,et al.  Mucoepidermoid carcinoma involving Warthin tumor. A report of five cases and review of the literature. , 2000, American journal of clinical pathology.

[16]  I. Sugano,et al.  Mucoepidermoid carcinoma arising in Warthin's tumour of the parotid gland: report of two cases with histopathological, ultrastructural and immunohistochemical studies , 1998, Histopathology.

[17]  G. Seifert.  Bilateral mucoepidermoid carcinomas arising in bilateral pre-existing Warthin's tumours of the parotid gland. , 1997, Oral oncology.

[18]  C. Land,et al.  Salivary gland tumors among atomic bomb survivors, 1950‐1987 , 1997, Cancer.

[19]  D. Gnepp,et al.  Synchronous tumors arising in a single major salivary gland , 1989 .

[20]  S. Gadient,et al.  Mucoepidermoid carcinoma arising within a Warthin's tumor. , 1975, Oral surgery, oral medicine, and oral pathology.