A mixture approach to the mechanics of the human intervertebral disc

A finite deformation model for charged hydrated tissues, such as the intervertebral tissue, is developed. The model predicts not only the response to a mechanical load but also to a chemical load. This response is characterised by ion diffusion, fluid flow relative to the solid matrix and osmotic pressure. The reasonable agreement between experiment and prediction of the model supports its physical basis.

[1]  R. M. Bowen,et al.  Incompressible porous media models by use of the theory of mixtures , 1980 .

[2]  Stephen Whitaker,et al.  ADVANCES IN THEORY OF FLUID MOTION IN POROUS MEDIA , 1969 .

[3]  D. Dalgleish An introduction to physical properties of large molecules in solution: by E G Richards. pp 266. IUPAB Biophysics Series, Cambridge University Press. 1980. £18 and £5.95 (paperback) , 1981 .

[4]  A. Maroudas,et al.  Biophysical chemistry of cartilaginous tissues with special reference to solute and fluid transport. , 1975, Biorheology.

[5]  V C Mow,et al.  The significance of electromechanical and osmotic forces in the nonequilibrium swelling behavior of articular cartilage in tension. , 1981, Journal of biomechanical engineering.

[6]  R. E. Craine,et al.  CONTINUUM THEORIES OF MIXTURES: BASIC THEORY AND HISTORICAL DEVELOPMENT , 1976 .

[7]  W M Lai,et al.  A finite deformation theory for cartilage and other soft hydrated connective tissues--I. Equilibrium results. , 1990, Journal of biomechanics.

[8]  William G. Gray,et al.  General conservation equations for multi-phase systems: 1. Averaging procedure , 1979 .

[9]  E. Richards An introduction to the physical properties of large molecules in solutions / E.G. Richards , 1980 .

[10]  van Dh Dick Campen,et al.  A mixture approach to the mechanics of skin. , 1987, Journal of biomechanics.

[11]  A. Grodzinsky,et al.  The kinetics of chemically induced nonequilibrium swelling of articular cartilage and corneal stroma. , 1987, Journal of biomechanical engineering.

[12]  A. Maroudas,et al.  Swelling pressures of proteoglycans at the concentrations found in cartilaginous tissues. , 1979, Biorheology.

[13]  J. C. Slattery,et al.  Momentum, Energy and Mass Transfer in Continua , 1976 .