Systemic amyloidosis of beta 2-microglobulin type: a complication of long-term haemodialysis.

A patient receiving long-term haemodialysis developed systemic amyloidosis, which was shown immunohistochemically to be of beta 2-microglobulin type, a previously unrecognised form of systemic amyloidosis. Histologically, the amyloid deposits were closely associated with foci of acute and granulomatous inflammation and vasculitis, although it was not clear if the amyloid deposits directly caused the inflammatory process, or if amyloid was deposited preferentially in areas of inflammation of uncertain aetiology.

[1]  A. Davenport,et al.  Dialysis arthropathy: amyloid or iron? , 1987, British medical journal.

[2]  D. Warrell,et al.  Oxford textbook of medicine , 1983, The Ulster Medical Journal.

[3]  C. Rudge.  Acquired cystic disease of the kidney: serious or irrelevant? , 1986, British medical journal.

[4]  D. Page,et al.  Tumoral amyloidosis of bone of beta 2-microglobulin origin in association with long-term hemodialysis: a new type of amyloid disease. , 1986, Human pathology.

[5]  O. Toupance,et al.  β2-MICROGLOBULIN-ASSOCIATED AMYLOIDOSIS IN CHRONIC HAEMODIALYSIS PATIENTS , 1986, The Lancet.

[6]  M. Pepys,et al.  HAEMODIALYSIS VERSUS CAPD: EQUAL PREDISPOSITION TO AMYLOIDOSIS? , 1986, The Lancet.

[7]  F. Gejyo,et al.  Serum levels of beta 2-microglobulin as a new form of amyloid protein in patients undergoing long-term hemodialysis. , 1986, The New England journal of medicine.

[8]  B. Frangione,et al.  Beta-2 microglobulin is an amyloidogenic protein in man. , 1985, The Journal of clinical investigation.

[9]  T. Morita,et al.  Amyloidosis of a possible new type in patients receiving long-term hemodialysis. , 1985, Archives of pathology & laboratory medicine.

[10]  M Arakawa,et al.  A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin. , 1985, Biochemical and biophysical research communications.

[11]  F. Watt,et al.  Hepatic copper distribution in primary biliary cirrhosis shown by the scanning proton microprobe. , 1985, Journal of clinical pathology.

[12]  A. Schwarz,et al.  Carpal tunnel syndrome: a major complication in long-term hemodialysis patients. , 1984, Clinical nephrology.

[13]  P. Altmeyer,et al.  Deposition of an amyloid-like substance as a possible complication of regular dialysis treatment. , 1983, Contributions to nephrology.

[14]  A. Morley,et al.  Accumulation of silicone elastomer in regular dialysis. , 1983, Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association.

[15]  A. Goldberg,et al.  Peripheral nerve entrapment syndromes in chronic hemodialysis patients. , 1982, Nephron.

[16]  T. Koyama,et al.  Red blood cell deformability in renal failure. , 1982, Nephron.

[17]  M. Dunnill,et al.  Acquired cystic disease of the kidneys: a hazard of long-term intermittent maintenance haemodialysis. , 1977, Journal of clinical pathology.

[18]  P. A. Peterson,et al.  The complete amino acid sequence of beta 2-microglobulin. , 1973, Biochemistry.