Extraction of vector dipoles from bathtub ECG leads for single and double ellipsoidal phantoms

This paper deals with a complex problem in scientific sensing and imaging. To overcome some inherent problems in the conventional ECG (Electrocardiogram), we investigate in depth an ‘unassisted’ approach which enables ECG measurement without the placement of sensing leads on the body. Specifically, it uses a bathtub at home with tap water in it and passive sensing leads placed on its inner surface – while the subject lies in it. In this investigation we use a widely accepted assumption that the electrical activity of the heart may be, largely, represented by a 3-D time-varying Current Dipole (3D-CD). To determine the sensing matrix responsible for transforming the 3D-CD into the potential distribution on the bathtub’s internal surface, the 3D-CD signals are applied to a bathtub-containing-ellipsoid model in COMSOL tool. The sensing matrix thereby estimated is then utilized to back reconstruct the 3D-CD signals from the bathtub leads signals. NRMSEs (Normalized Root-Mean-Squared Errors) on the order of 0.02 to 0.05 are observed. The approach is also successfully extended to the case of two ellipsoids, one inside the other, representing a pregnant female subject. Critically important from a practical standpoint, the paper examines sensitivity with respect to the locations of the two 3D-CDs in the bathtub, and reports the encouraging results. Images of the potential distribution in the composite volume in the bathtub are presented as well.

[1]  M. Ishijima Monitoring of electrocardiograms in bed without utilizing body surface electrodes , 1993, IEEE Transactions on Biomedical Engineering.

[2]  Paul Kurowski,et al.  Engineering Analysis with SolidWorks Simulation 2019 , 2009 .

[3]  D. B. Geselowitz,et al.  Multipole Representation for an Equivalent Cardiac Generator , 1960, Proceedings of the IRE.

[4]  Charles Sodini,et al.  An Ear-Worn Vital Signs Monitor , 2015, IEEE Transactions on Biomedical Engineering.

[5]  D. Geselowitz On bioelectric potentials in an inhomogeneous volume conductor. , 1967, Biophysical journal.

[6]  Tsuyoshi Kato,et al.  Capacitive Sensing of Electrocardiographic Potential Through Cloth From the Dorsal Surface of the Body in a Supine Position: A Preliminary Study , 2007, IEEE Transactions on Biomedical Engineering.

[7]  Nigel H. Lovell,et al.  Using information technology to improve the management of chronic disease , 2003, The Medical journal of Australia.

[8]  K. Yamakoshi,et al.  Measurement of electrocardiograms in a bath through tap water utilizing capacitive coupling electrodes placed outside the bathtub wall , 2017, Biomedical engineering online.

[9]  H. Schwan,et al.  Capacitive Properties of Body Tissues , 1957, Circulation research.

[10]  D B Geselowitz Electric and magnetic field of the heart. , 1973, Annual review of biophysics and bioengineering.

[11]  Pratheek Michael,et al.  Simulation Studies on ECG Vector Dipole Extraction in Liquid Medium , 2017 .

[12]  Hervé Delingette,et al.  Noninvasive Personalization of a Cardiac Electrophysiology Model From Body Surface Potential Mapping , 2017, IEEE Transactions on Biomedical Engineering.

[13]  Ki H. Chon,et al.  Novel Electrodes for Underwater ECG Monitoring , 2014, IEEE Transactions on Biomedical Engineering.

[14]  Vijay K. Jain,et al.  A New Technique for Monitoring Heart Signals-Part I: Instrumentation Design , 1986, IEEE Transactions on Biomedical Engineering.

[15]  T. Ten Have,et al.  Outcomes of a telehealth intervention for homebound older adults with heart or chronic respiratory failure: a randomized controlled trial. , 2012, The Gerontologist.

[16]  Sabine Van Huffel,et al.  A Novel Algorithm for the Automatic Detection of Sleep Apnea From Single-Lead ECG , 2015, IEEE Transactions on Biomedical Engineering.

[17]  Jesse Jur,et al.  Fabric-Based Wearable Dry Electrodes for Body Surface Biopotential Recording , 2016, IEEE Transactions on Biomedical Engineering.

[18]  Yu Chen,et al.  Saturation of the Right-Leg Drive Amplifier in Low-Voltage ECG Monitors , 2015, IEEE Transactions on Biomedical Engineering.

[19]  Ko Keun Kim,et al.  The ECG measurement in the bathtub using the insulated electrodes , 2004, The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[20]  C. V. Nelson,et al.  Determination of the Resultant Dipole of the Heart from Measurements on the Body Surface , 1954 .

[21]  Yijun Wang,et al.  Skin-Potential Variation Insensitive Dry Electrodes for ECG Recording , 2017, IEEE Transactions on Biomedical Engineering.

[22]  Robert Plonsey,et al.  Bioelectricity: A Quantitative Approach Duke University’s First MOOC , 2013 .

[23]  Yuji Higashi,et al.  Development and clinical evaluation of a home healthcare system measuring in toilet, bathtub and bed without attachment of any biological sensors , 2010, Proceedings of the 10th IEEE International Conference on Information Technology and Applications in Biomedicine.

[24]  Vijay K. Jain,et al.  A New Technique for Monitoring Heart Signals-Part II: Orthogonal Lead Extraction , 1986, IEEE Transactions on Biomedical Engineering.

[25]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[26]  Seung Bae Hong,et al.  Patient-Specific Identification of Optimal Ubiquitous Electrocardiogram (U-ECG) Placement Using a Three-Dimensional Model of Cardiac Electrophysiology , 2013, IEEE Transactions on Biomedical Engineering.