论文信息 - ELF fields and photooxidation yielding lethal effects on cancer cells

ELF fields and photooxidation yielding lethal effects on cancer cells

The lethal effect on human cancer cells was studied under three types of treatment: A) an ELF pulsed sinusoidal of 50 Hz electromagnetic field (PEMF) with amplitudes between 10 and 55 mT; B) the field and a cytostatic agent (actinomycin-C); and C) the field, the cytostatic agent, which has a photodynamic effect, and exposure to a halogen lamp. The results show a decreasing vitality of human K-562 and U-937 cancer cells in suspension with each additional treatment. Combination with other parameters as hyperthermia and/or hyperacidity could yield high killing rates by this noninvasive method.

[1] E. Cundari,et al. Normal and cancer‐prone human cells respond differently to extremely low frequency magnetic fields , 2001, FEBS letters.

[2] K. Asano,et al. Induction of apoptosis in human leukemic cells by magnetic fields. , 1997, The Japanese journal of physiology.

[3] S. Tofani,et al. Increased mouse survival, tumor growth inhibition and decreased immunoreactive p53 after exposure to magnetic fields , 2002, Bioelectromagnetics.

[4] H. Berg,et al. Problems of weak electromagnetic field effects in cell biology. , 1999, Bioelectrochemistry and bioenergetics.

[5] H. Berg,et al. Photodynamic effect on cancer cells influenced by electromagnetic fields. , 2001, Journal of photochemistry and photobiology. B, Biology.

[6] L. E. Anderson,et al. EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELDS , 1990 .

[7] M. Repacholi,et al. Interaction of static and extremely low frequency electric and magnetic fields with living systems: health effects and research needs. , 1999, Bioelectromagnetics.

[8] D. Weiss,et al. Effects of 50 Hz EMF exposure on micronucleus formation and apoptosis in transformed and nontransformed human cell lines , 1998 .