Aging-related differences in cerebral capillary blood flow in anesthetized rats

[1]  A. Linninger,et al.  Cerebral Microcirculation and Oxygen Tension in the Human Secondary Cortex , 2013, Annals of Biomedical Engineering.

[2]  Arne Møller,et al.  The capillary dysfunction hypothesis of Alzheimer's disease , 2013, Neurobiology of Aging.

[3]  A. MacGibbon,et al.  Age-related memory decline is associated with vascular and microglial degeneration in aged rats , 2012, Behavioural Brain Research.

[4]  D. Kleinfeld,et al.  Two-Photon Microscopy as a Tool to Study Blood Flow and Neurovascular Coupling in the Rodent Brain , 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[5]  Johannes E. Schindelin,et al.  Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.

[6]  Nozomi Nishimura,et al.  In vivo two-photon excited fluorescence microscopy reveals cardiac- and respiration-dependent pulsatile blood flow in cortical blood vessels in mice. , 2012, American journal of physiology. Heart and circulatory physiology.

[7]  F. Helmchen,et al.  In vivo labeling of cortical astrocytes with sulforhodamine 101 (SR101). , 2012, Cold Spring Harbor protocols.

[8]  M. Chakravarty,et al.  Brain Energy Metabolism and Blood Flow Differences in Healthy Aging , 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[9]  Katja Schenke-Layland,et al.  Age-Related Changes in the Elastic Tissue of the Human Aorta , 2011, Journal of Vascular Research.

[10]  Leif Østergaard,et al.  The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism , 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[11]  Jean-Claude Tardif,et al.  Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice. , 2011, American journal of physiology. Heart and circulatory physiology.

[12]  Javier DeFelipe,et al.  The Evolution of the Brain, the Human Nature of Cortical Circuits, and Intellectual Creativity , 2011, Front. Neuroanat..

[13]  W. Brown,et al.  Review: Cerebral microvascular pathology in ageing and neurodegeneration , 2011, Neuropathology and applied neurobiology.

[14]  Emiri T. Mandeville,et al.  Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue , 2010, Nature Methods.

[15]  Stefan A. Carp,et al.  The effect of different anesthetics on neurovascular coupling , 2010, NeuroImage.

[16]  R. Buxton.  Neuroenergetics Review Article , 2022 .

[17]  Yutaka Tomita,et al.  RBC velocities in single capillaries of mouse and rat brains are the same, despite 10-fold difference in body size , 2010, Brain Research.

[18]  Arthur F. Kramer,et al.  Resting hippocampal blood flow, spatial memory and aging , 2010, Brain Research.

[19]  B. Carnes,et al.  Basal and hypercapnia-altered cerebrovascular perfusion predict mild cognitive impairment in aging rodents , 2009, Neuroscience.

[20]  Jennifer L. Mozolic,et al.  Human Neuroscience , 2022 .

[21]  S. Ito,et al.  Some mechanical aspects of arterial aging: physiological overview based on pulse wave analysis , 2009, Therapeutic advances in cardiovascular disease.

[22]  Michael Hermes,et al.  Resting cerebral blood flow, attention, and aging , 2009, Brain Research.

[23]  A. Fleisher,et al.  Effects of aging on cerebral blood flow, oxygen metabolism, and blood oxygenation level dependent responses to visual stimulation , 2009, Human brain mapping.

[24]  Anna Devor,et al.  Oxygen advection and diffusion in a three- dimensional vascular anatomical network. , 2008, Optics express.

[25]  Yutaka Tomita,et al.  Frequency distribution function of red blood cell velocities in single capillaries of the rat cerebral cortex using intravital laser-scanning confocal microscopy with high- speed camera , 2008 .

[26]  Anders M. Dale,et al.  A vascular anatomical network model of the spatio-temporal response to brain activation , 2008, NeuroImage.

[27]  B. Douglas Ward,et al.  A novel technique for modeling susceptibility-based contrast mechanisms for arbitrary microvascular geometries: The finite perturber method , 2008, NeuroImage.

[28]  Ş. Demirkaya,et al.  Normal blood flow velocities of basal cerebral arteries decrease with advancing age: a transcranial Doppler sonography study. , 2008, The Tohoku journal of experimental medicine.

[29]  Alan P. Koretsky,et al.  Spatial flow-volume dissociation of the cerebral microcirculatory response to mild hypercapnia , 2006, NeuroImage.

[30]  D. Poole,et al.  Effects of aging on capillary geometry and hemodynamics in rat spinotrapezius muscle. , 2003, American journal of physiology. Heart and circulatory physiology.

[31]  David R. Riddle,et al.  Microvascular plasticity in aging , 2003, Ageing Research Reviews.

[32]  K. Uğurbil,et al.  Effect of Basal Conditions on the Magnitude and Dynamics of the Blood Oxygenation Level-Dependent fMRI Response , 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[33]  P. Luiten,et al.  Cerebral microvascular pathology in aging and Alzheimer's disease , 2001, Progress in Neurobiology.

[34]  D. Ingram,et al.  Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function , 2000, Neurobiology of Aging.

[35]  B. Rosen,et al.  Evidence of a Cerebrovascular Postarteriole Windkessel with Delayed Compliance , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[36]  S. Bennett,et al.  Effects of moderate caloric restriction on cortical microvascular density and local cerebral blood flow in aged rats☆ , 1999, Neurobiology of Aging.

[37]  D. Kleinfeld,et al.  Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[38]  V. Cassone,et al.  Ocular and regional cerebral blood flow in aging Fischer-344 rats. , 1998, Journal of applied physiology.

[39]  Guido Gerig,et al.  Three-dimensional multi-scale line filter for segmentation and visualization of curvilinear structures in medical images , 1998, Medical Image Anal..

[40]  A. Hudetz,et al.  Blood Flow in the Cerebral Capillary Network: A Review Emphasizing Observations with Intravital Microscopy , 1997, Microcirculation.

[41]  P. Rüegsegger,et al.  A new method for the model‐independent assessment of thickness in three‐dimensional images , 1997 .

[42]  R. Buxton,et al.  A Model for the Coupling between Cerebral Blood Flow and Oxygen Metabolism during Neural Stimulation , 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[43]  B R Rosen,et al.  Mr contrast due to intravascular magnetic susceptibility perturbations , 1995, Magnetic resonance in medicine.

[44]  A. Villringer,et al.  Capillary perfusion of the rat brain cortex. An in vivo confocal microscopy study. , 1994, Circulation research.

[45]  J. Atkinson,et al.  In vivo cerebrovascular reactivity in Wistar and Fischer 344 rat strains during aging. , 1993, The American journal of physiology.

[46]  M. Trevisan,et al.  Hematocrit, blood pressure, and hypertension. The Gubbio Population Study. , 1992, Hypertension.

[47]  R. McCuskey,et al.  In vivo microscopic studies of age-related changes in the structure and the reactivity of cerebral microvessels , 1992, Mechanisms of Ageing and Development.

[48]  P M Bennett,et al.  Erythrocyte size, number and haemoglobin content in vertebrates , 1991, British journal of haematology.

[49]  D. Heistad,et al.  Effects of aging on mechanics and composition of cerebral arterioles in rats. , 1990, Circulation research.

[50]  K. Bättig,et al.  Effects of aging and vincamine derivatives on pericapillary microenvironment: stereological characterization of the cerebral capillary network , 1990, Neurobiology of Aging.

[51]  Richard S. J. Frackowiak,et al.  Cerebral blood flow, blood volume and oxygen utilization. Normal values and effect of age. , 1990, Brain : a journal of neurology.

[52]  H. Goldman,et al.  Age-related changes in regional cerebral blood flow and behavior in Sprague-Dawley rats , 1988, Neurobiology of Aging.

[53]  H. Goldman,et al.  Correlation of behavioral and cerebrovascular functions in the aging rat , 1987, Neurobiology of Aging.

[54]  H. Weiss,et al.  Cerebral oxygen consumption and blood flow in Fischer-344 rats of different ages , 1987, Neurobiology of Aging.

[55]  F Shishido,et al.  Reduction in regional cerebral metabolic rate of oxygen during human aging. , 1986, Stroke.

[56]  D Comar,et al.  Regional Cerebral Blood Flow and Oxygen Consumption in Human Aging , 1984, Stroke.

[57]  T. Samorajski,et al.  Age-related changes in rat brain capillaries , 1983, Neurobiology of Aging.

[58]  M. A. Bell,et al.  Morphometric comparison of hippocampal microvasculature in ageing and demented people: Diameters and densities , 1981, Acta Neuropathologica.

[59]  E. London,et al.  Regional cerebral blood flow during development and ageing of the rat brain. , 1981, Brain : a journal of neurology.

[60]  G. Pawlik,et al.  Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study , 1981, Brain Research.

[61]  W. Meier-Ruge,et al.  Stereological changes in the capillary network and nerve cells of the aging human brain , 1980, Mechanisms of Ageing and Development.

[62]  O. Hunziker,et al.  The aging human cerebral cortex: a stereological characterization of changes in the capillary net. , 1979, Journal of gerontology.

[63]  S. Lefrak,et al.  The oxyhemoglobin dissociation curve in health and disease. Role of 2,3-diphosphoglycerate. , 1974, The American journal of medicine.

[64]  C. Ambrose.  Neuroangiogenesis: a vascular basis for Alzheimer's disease and cognitive decline during aging. , 2012, Journal of Alzheimer's disease : JAD.

[65]  David R. Riddle,et al.  Regulation of Cerebrovascular Aging , 2007 .

[66]  D. gallagher-Thompson,et al.  Blood pressure and hypertension , 2004 .

[67]  R N Kalaria,et al.  Cerebral vessels in ageing and Alzheimer's disease. , 1996, Pharmacology & therapeutics.

[68]  M. Nakai,et al.  Effects of aging and chronic hypertension on cerebral blood flow and cerebrovascular CO2 reactivity in the rat. , 1995, Gerontology.

[69]  F Shishido,et al.  Age-related decline of cerebral oxygen metabolism in normal population detected with positron emission tomography. , 1992, Neurological research.

[70]  L. Deecke,et al.  [Age and whole blood viscoelasticity. A risk factor study]. , 1991, Acta Medica Austriaca.

[71]  M. Harrison.  Influence of haematocrit in the cerebral circulation. , 1989, Cerebrovascular and brain metabolism reviews.

[72]  S. Rapoport,et al.  Cerebral Blood Flow and Oxidative Metabolism in Conscious Fischer‐344 Rats of Different Ages , 1983, Journal of neurochemistry.

[73]  E. London,et al.  Brain metabolism and blood flow during development and aging of the Fischer-344 rat. , 1982, Experimental brain research.