Blood Group Typing: From Classical Strategies to the Application of Synthetic Antibodies Generated by Molecular Imprinting

Blood transfusion requires a mandatory cross-match test to examine the compatibility between donor and recipient blood groups. Generally, in all cross-match tests, a specific chemical reaction of antibodies with erythrocyte antigens is carried out to monitor agglutination. Since the visual inspection is no longer useful for obtaining precise quantitative information, therefore there is a wide variety of different technologies reported in the literature to recognize the agglutination reactions. Despite the classical methods, modern biosensors and molecular blood typing strategies have also been considered for straightforward, accurate and precise analysis. The interfacial part of a typical sensor device could range from natural antibodies to synthetic receptor materials, as designed by molecular imprinting and which is suitably integrated with the transducer surface. Herein, we present a comprehensive overview of some selected strategies extending from traditional practices to modern procedures in blood group typing, thus to highlight the most promising approach among emerging technologies.

[1]  Lei Ye,et al.  Molecular imprinting: Synthetic materials as substitutes for biological antibodies and receptors , 2008 .

[2]  Michael J. Schöning,et al.  Handheld measurement device for field-effect sensor structures: Practical evaluation and limitations , 2007 .

[3]  L. Castilho,et al.  Blood group genotyping , 2004 .

[4]  R. Schirhagl,et al.  Atrazine detection based on antibody replicas , 2011 .

[5]  M. Smyth,et al.  Detection of blood group antigens utilising immobilised antibodies and surface plasmon resonance. , 1997, Journal of immunological methods.

[6]  X. Qiao,et al.  The biomimetic immunoassay based on molecularly imprinted polymer: a comprehensive review of recent progress and future prospects. , 2011, Journal of food science.

[7]  Gil Garnier,et al.  Validation of paper-based assay for rapid blood typing. , 2012, Analytical chemistry.

[8]  U. Cobet,et al.  BLOOD GROUP TYPING BY ULTRASOUND BACKSCATTERING—QUANTITATIVE MEASUREMENTS OF AGGLUTINATES AND THEIR SHEAR-DEPENDENT BEHAVIOR , 2000 .

[9]  Franz L Dickert,et al.  Synthetic receptors for selectively detecting erythrocyte ABO subgroups. , 2009, Analytica chimica acta.

[10]  Franz L Dickert,et al.  Sensor strategies for microorganism detection—from physical principles to imprinting procedures , 2003, Analytical and bioanalytical chemistry.

[11]  C. Gassner,et al.  Matrix-assisted laser desorption/ionisation, time-of-flight mass spectrometry-based blood group genotyping--the alternative approach. , 2013, Transfusion medicine reviews.

[12]  W. Kutner,et al.  Imprinted polymer-based enantioselective acoustic sensor using a quartz crystal microbalance , 1999 .

[13]  K Mosbach,et al.  Plastic antibodies: developments and applications. , 1998, Trends in biotechnology.

[14]  Wim Malomgré,et al.  Recent and future trends in blood group typing , 2009, Analytical and bioanalytical chemistry.

[15]  C. Westhoff,et al.  Chapter 6 – ABO and Related Antigens and Antibodies , 2007 .

[16]  Sergey A Piletsky,et al.  Molecularly imprinted polymers in clinical diagnostics--future potential and existing problems. , 2006, Medical engineering & physics.

[17]  F. Dickert,et al.  Modifying polymers by self-organisation for the mass-sensitive detection of environmental and biogeneous analytes , 2004 .

[18]  Imprinting as a versatile platform for sensitive materials – nanopatterning of the polymer bulk and surfaces , 2005 .

[19]  Zofia Iskierko,et al.  Bioinspired intelligent molecularly imprinted polymers for chemosensing: A mini review , 2015 .

[20]  Peter A Lieberzeit,et al.  Sensors for bioanalytes by imprinting--polymers mimicking both biological receptors and the corresponding bioparticles. , 2009, Biosensors & bioelectronics.

[21]  K. Landsteiner,et al.  Ueber Agglutinationserscheinungen normalen menschlichen Blutes , 1901 .

[22]  M. Prager Molecular genetic blood group typing by the use of PCR‐SSP technique , 2007, Transfusion.

[23]  S. Knowles,et al.  Chapter 19 – Blood cell antigens and antibodies: erythrocytes, platelets, and granulocytes , 2006 .

[24]  Oleksiy Krupin,et al.  Selective capture of human red blood cells based on blood group using long-range surface plasmon waveguides. , 2014, Biosensors & bioelectronics.

[25]  Hao Dai,et al.  Synthesis and analytical applications of molecularly imprinted polymers on the surface of carbon nanotubes: a review , 2015, Microchimica Acta.

[26]  Peter A Lieberzeit,et al.  Rapid bioanalysis with chemical sensors: novel strategies for devices and artificial recognition membranes , 2008, Analytical and bioanalytical chemistry.

[27]  T. Alizadeh Comparison of different methodologies for integration of molecularly imprinted polymer and electrochemical transducer in order to develop a paraoxon voltammetric sensor , 2010 .

[28]  Peter A. Lieberzeit,et al.  Chemical Sensors Based on Molecularly Imprinted Sol-Gel Materials † , 2010, Materials.

[29]  S. Kimura,et al.  Rapid quantitation of immunoglobulin G antibodies specific for blood group antigens A and B by surface plasmon resonance , 2005, Transfusion.

[30]  C. Paccapelo,et al.  Blood group genotyping for Jka/Jkb, Fya/Fyb, S/s, K/k, Kpa/Kpb, Jsa/Jsb, Coa/Cob, and Lua/Lub with microarray beads , 2008 .

[31]  F. Patat,et al.  Significance of mass and viscous loads discrimination for an AT-quartz blood group immunosensor , 1994 .

[32]  Anthony Turner,et al.  Too large to fit? Recent developments in macromolecular imprinting. , 2008, Trends in biotechnology.

[33]  Junfa Yin,et al.  Rapid and efficient chiral separation of nateglinide and its L-enantiomer on monolithic molecularly imprinted polymers. , 2005, Journal of chromatography. A.

[34]  Wanida Laiwattanapaisal,et al.  A novel paper-based assay for the simultaneous determination of Rh typing and forward and reverse ABO blood groups. , 2015, Biosensors & bioelectronics.

[35]  K. Mosbach,et al.  Molecularly imprinted polymers and their use in biomimetic sensors. , 2000, Chemical reviews.

[36]  F. Dickert,et al.  Synthetic receptors for chemical sensors--subnano- and micrometre patterning by imprinting techniques. , 2004, Biosensors & bioelectronics.

[37]  F. Dickert,et al.  Application of yeast imprinting in biotechnology and process control. , 2009, The Analyst.

[38]  F. Dickert,et al.  Softlithography in Chemical Sensing – Analytes from Molecules to Cells , 2005, Sensors (Basel, Switzerland).

[39]  O. Illoh,et al.  Extended blood group molecular typing and next-generation sequencing. , 2014, Transfusion medicine reviews.

[40]  A. Afzal,et al.  Bioimprinting strategies: from soft lithography to biomimetic sensors and beyond. , 2013, Biotechnology advances.

[41]  Peter A Lieberzeit,et al.  Comparing biomimetic and biological receptors for insulin sensing. , 2010, Chemical communications.

[42]  F. Dickert,et al.  Bioimprinting of polymers and sol-gel phases. Selective detection of yeasts with imprinted polymers. , 2002, Analytical chemistry.

[43]  S. Shinkai,et al.  Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions. , 2004, Biosensors & bioelectronics.

[44]  Wei Shen,et al.  Paper-based device for rapid typing of secondary human blood groups , 2013, Analytical and Bioanalytical Chemistry.

[45]  Franz L Dickert,et al.  Biomimetic ABO blood-group typing. , 2006, Angewandte Chemie.

[46]  Franz L. Dickert,et al.  Selective Microorganism Detection with Cell Surface Imprinted Polymers , 2001 .

[47]  K. Shea,et al.  Selective protein capture by epitope imprinting. , 2006, Angewandte Chemie.

[48]  James Noble,et al.  The rational development of molecularly imprinted polymer-based sensors for protein detection. , 2011, Chemical Society reviews.

[49]  Peter A Lieberzeit,et al.  Imprinted sol-gel materials for monitoring degradation products in automotive oils by shear transverse wave. , 2010, Analytica chimica acta.

[50]  Dong Sung Kim,et al.  Disposable integrated microfluidic biochip for blood typing by plastic microinjection moulding. , 2006, Lab on a chip.

[51]  Blood group typing based on recording the elastic scattering of laser radiation using the method of digital imaging , 2012 .

[52]  A. Katz,et al.  Synthesis of a confined class of chiral organic catalysts via bulk imprinting of silica , 2005 .

[53]  H. Lutz,et al.  Isotype‐specific detection of ABO blood group antibodies using a novel flow cytometric method , 2005, British journal of haematology.

[54]  Florence Chapuis-Hugon,et al.  Role of molecularly imprinted polymers for selective determination of environmental pollutants--a review. , 2008, Analytica chimica acta.

[55]  Michael Seul,et al.  A flexible array format for large‐scale, rapid blood group DNA typing , 2005, Transfusion.

[56]  A. Turner,et al.  Biotin-specific synthetic receptors prepared using molecular imprinting , 2004 .

[57]  Börje Sellergren,et al.  Molecularly imprinted polymers: a bridge to advanced drug delivery. , 2005, Advanced drug delivery reviews.

[58]  G. Wulff Molecular Imprinting in Cross‐Linked Materials with the Aid of Molecular Templates— A Way towards Artificial Antibodies , 1995 .

[59]  D. Boudreau,et al.  PCR‐free blood group genotyping using a nanobiosensor , 2015, Vox sanguinis.

[60]  G. Whitesides,et al.  Soft lithography for micro- and nanoscale patterning , 2010, Nature Protocols.

[61]  G. Garnier,et al.  The detection of blood group phenotypes using paper diagnostics , 2015, Vox sanguinis.