Ethics and ENDS

As debate persists over regulating electronic nicotine delivery systems (ENDS), those favouring liberal ENDS policies have advanced rights-based arguments privileging harm reduction to people who smoke over harm prevention to children and never-smokers. Recent ethical arguments advocate regulating ENDS to prioritise their harm reduction potential for people who currently smoke over any future harm to young never-smokers. In this article, we critically assess these arguments, in particular, the assumption that ethical arguments for prioritising the interests of young people do not apply to ENDS. We argue that, when the appropriate comparators are used, it is not clear the weight of ethical argument tips in favour of those who currently smoke and against young never-smokers. We also assert that arguments from a resource prioritisation context are not appropriate for analysing ENDS regulation, because ENDS are not a scarce resource. Further, we reject utilitarian arguments regarding maximising net population health benefits, as these do not adequately consider vulnerable groups' rights, or address the population distribution of benefits and harms. Lastly, we argue that one-directional considerations of harm reduction do not recognise that ENDS potentially increase harm to those who do not smoke and who would not otherwise have initiated nicotine use.

[1]  J. Samet,et al.  E-Cigarettes and Harm Reduction: An Artificial Controversy Instead of Evidence and a Well-Framed Decision Context. , 2021, American journal of public health.

[2]  N. Rigotti,et al.  Balancing Consideration of the Risks and Benefits of E-Cigarettes. , 2021, American journal of public health.

[3]  I. Abraham,et al.  The Decline in e-Cigarette Use Among Youth in the United States-An Encouraging Trend but an Ongoing Public Health Challenge. , 2021, JAMA network open.

[4]  Brian A. King,et al.  Characteristics of e-Cigarette Use Behaviors Among US Youth, 2020 , 2021, JAMA network open.

[5]  M. Blaha,et al.  The Promise and Peril of Vaping , 2020, Current Cardiology Reports.

[6]  S. Shiffman,et al.  The ethics of tobacco harm reduction: An analysis of e-cigarette availability from the perspectives of utilitarianism, bioethics, and public health ethics. , 2020, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

[7]  M. Magalhaes,et al.  Vaping restrictions: is priority to the young justified? , 2020, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

[8]  N. Eyal Rescuing vapers vs. rescuing smokers: the ethics. , 2020, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

[9]  C. McDonald,et al.  The Evolving Landscape of e-Cigarettes , 2020, Chest.

[10]  E. Stevens,et al.  E-cigarette Regulation: A Delicate Balance for Public Health. , 2020, Addiction.

[11]  Philip Gendall,et al.  Role of flavours in vaping uptake and cessation among New Zealand smokers and non-smokers: a cross-sectional study , 2020, Tobacco Control.

[12]  M. Munafo,et al.  Is e-cigarette use in non-smoking young adults associated with later smoking? A systematic review and meta-analysis , 2019, Tobacco Control.

[13]  P. Brennan,et al.  Are electronic nicotine delivery systems (ENDs) helping cigarette smokers quit? - A current evidence. , 2020, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[14]  E. Fernández,et al.  Passive exposure of non-smokers to E-Cigarette aerosols: Sensory irritation, timing and association with volatile organic compounds. , 2019, Environmental research.

[15]  T. Pechacek,et al.  Patterns and trends of dual use of e-cigarettes and cigarettes among U.S. adults, 2015–2018 , 2019, Preventive medicine reports.

[16]  R. Beaglehole,et al.  Nicotine without smoke: fighting the tobacco epidemic with harm reduction , 2019, The Lancet.

[17]  B. Freeman,et al.  BAT(NZ) draws on cigarette marketing tactics to launch Vype in New Zealand , 2019, Tobacco Control.

[18]  S. Chapman,et al.  The Gateway Effect of E-cigarettes: Reflections on Main Criticisms. , 2019, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

[19]  S. Batra,et al.  Immunological and toxicological risk assessment of e-cigarettes , 2018, European Respiratory Review.

[20]  Laura A. Gibson,et al.  Association Between Initial Use of e-Cigarettes and Subsequent Cigarette Smoking Among Adolescents and Young Adults: A Systematic Review and Meta-analysis , 2017, JAMA pediatrics.

[21]  Brian A. King,et al.  National and State Trends in Sales of Cigarettes and E-Cigarettes, U.S., 2011-2015. , 2017, American journal of preventive medicine.

[22]  G. Guyatt,et al.  Electronic nicotine delivery systems and/or electronic non-nicotine delivery systems for tobacco smoking cessation or reduction: a systematic review and meta-analysis , 2017, BMJ Open.

[23]  J. Cappella,et al.  Youth-Targeted E-cigarette Marketing in the US. , 2017, Tobacco regulatory science.

[24]  Y. V. D. Eijk Ethics of tobacco harm reduction from a liberal perspective , 2016 .

[25]  G. Annas,et al.  (Public) Health and Human Rights in Practice. , 2016, Journal of health politics, policy and law.

[26]  E. Fernández,et al.  Particulate Matter from Electronic Cigarettes and Conventional Cigarettes: a Systematic Review and Observational Study , 2015, Current Environmental Health Reports.

[27]  S. Michie,et al.  Real-world effectiveness of e-cigarettes when used to aid smoking cessation: a cross-sectional population study , 2014, BDJ.

[28]  J. Kleinig The Ethics of Harm Reduction , 2008, Substance use & misuse.

[29]  D. Shelley,et al.  The Fourth Pillar of the Framework Convention on Tobacco Control: Harm Reduction and the International Human Right to Health , 2006, Public health reports.

[30]  S. Gruskin What are health and human rights? , 2007, Lancet.

[31]  L. Kozlowski Harm reduction, public health, and human rights: smokers have a right to be informed of significant harm reduction options. , 2002, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.