3‐Chloro‐3‐(diphenylmethoxy)‐1,1,1,5,5,5‐hexamethyltrisiloxane

[309963-45-9] C19H29ClO3Si3 (MW 425.14) InChI = 1S/C19H29ClO3Si3/c1-24(2,3)22-26(20,23-25(4,5)6)21-19(17-13-9-7-10-14-17)18-15-11-8-12-16-18/h7-16,19H,1-6H3 InChIKey = MXYRUZAVJVIZOX-UHFFFAOYSA-N (reagent used as a 5′-silyl protecting group for ribonucleoside phosphoramidite synthesis)1 Alternative Names:  benzhydryloxybis(trimethylsiloxy)chlorosilane, BzH-Cl. Physical Data: mp 0.25 °C; bp 135–140 °C; d 1.0345 g cm−3. Solubility: most organic solvents (tetrahydrofuran, dimethylformamide, dichloromethane). Form Supplied in: liquid; commercially available from Gelest. Preparation: the reagent is produced through the reaction between diphenylmethanol and bis(trimethylsiloxy)dichlorosilane.1 A related silyl chloride, bis(trimethylsiloxy)cyclododecyloxysilyl chloride (DODCl), is produced using analogous methods, by the reaction of cyclododecanol with bis(trimethylsiloxy)dichlorosilane. Handling, Storage, and Precautions: handling and precautions are unknown. Should be stored in a cool (< 5 °C) and anhydrous environment.

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