Evaluation of Clinical Outcome, Drug Utilization and Effect on Liver Enzymes of Anti-epileptics in Epileptic Patients

Anti-epileptic drugs of various classifications are used to treat different types of seizures. A prospective experimental study is done in 50 epilepsy patients taking atleast 1 anti-epileptic drug in a tertiary care hospital, Kerala, India. The objective of the study is to determine the clinical outcome and drug utilization of anti-epileptics along with the effect of anti-epileptics on serum liver enzymes such as ALP, AST and ALP. Clinical outcome of the patients were obtained using determining the seizure control obtained by the patients. Drug utilization is determined using prescription analysis. Effect in liver enzymes is evaluated using collecting residual blood sample of the patients and determined using semi-auto analyzer and colorimetry.