Emerging technologies and safety concerns: a condensed review of environmental life cycle risks in the nano-world

The functionalities of nano-materials are accompanied by features that are in collision with the postulates of environmental friendliness and sustainability. Nano-related research, part of which is nano-safety, is gaining momentum worldwide, but there is a limited body of knowledge about mechanisms such as the degradation, surface modification and transformation of nanoparticles. This study aims to provide a brief survey on the challenges that researchers and engineers face when attempting to assess the environmental impacts of nano-based products. The applicability of the life cycle assessment method to nanotechnology is briefly explored. The advancement of nano-specific life cycle approaches capable of evaluating the sustainability of these emerging technologies depends on further research on material inventories, the energy efficiency of manufacturing processes, the transport and fate of nanoparticles in the environment, health risks and mitigation techniques. Specialized nano-based product-related databases are still needed to track engineered nano-materials (ENMs) in the environment and to facilitate life cycle inventories and assessment. Permissible exposure limits for key ENMs in the workplace and standardized handling protocols for ENMs are not widely available. Properties that increase their toxicity and bioaccumulation are being increasingly investigated. The dissemination of information to the general public related to risk management is rather sporadic, and the suitability of current regulation for controlling environmental pollution by ENM is subject to continued discussion. Taking into account the environment health and safety challenges mentioned, a suitable expertise and information dissemination network is proposed to take the responsible application of nanotechnology forward in the developing world context.

[1]  T. Gutowski,et al.  Minimum exergy requirements for the manufacturing of carbon nanotubes , 2010, Proceedings of the 2010 IEEE International Symposium on Sustainable Systems and Technology.

[2]  Vicki Stone,et al.  Research priorities to advance eco-responsible nanotechnology. , 2009, ACS nano.

[3]  Vikas Khanna,et al.  Carbon nanofiber polymer composites: evaluation of life cycle energy use. , 2009, Environmental science & technology.

[4]  Mirko Miseljic,et al.  Life-cycle assessment of engineered nanomaterials: a literature review of assessment status , 2014, Journal of Nanoparticle Research.

[5]  G. Stucky,et al.  Biomagnification of cadmium selenide quantum dots in a simple experimental microbial food chain. , 2011, Nature nanotechnology.

[6]  Arturo A. Keller,et al.  Global life cycle releases of engineered nanomaterials , 2013, Journal of Nanoparticle Research.

[7]  T. Glenn,et al.  Comparative phototoxicity of nanoparticulate and bulk ZnO to a free-living nematode Caenorhabditis elegans: the importance of illumination mode and primary particle size. , 2011, Environmental pollution.

[8]  Vikas Khanna,et al.  Comparative life cycle assessment: Reinforcing wind turbine blades with carbon nanofibers , 2010, Proceedings of the 2010 IEEE International Symposium on Sustainable Systems and Technology.

[9]  Peter Wick,et al.  Nanotoxicology: an interdisciplinary challenge. , 2011, Angewandte Chemie.

[10]  Ashok Vaseashta,et al.  Nanostructures in environmental pollution detection, monitoring, and remediation , 2007 .

[11]  V. Castranova,et al.  Comparison of the Biological Activity Between Ultrafine and Fine Titanium Dioxide Particles in RAW 264.7 Cells Associated with Oxidative Stress , 2008, Journal of toxicology and environmental health. Part A.

[12]  Vikas Khanna,et al.  Carbon Nanofiber Production , 2008 .

[13]  Srdjan Glisovic,et al.  The state of play in disseminating LCM practices in the Western Balkan region: the attitude of Serbian SMEs , 2015, The International Journal of Life Cycle Assessment.

[14]  X. Lou,et al.  Carbon-supported ultra-thin anatase TiO2 nanosheets for fast reversible lithium storage , 2011 .

[15]  Robert N Grass,et al.  In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility. , 2006, Environmental science & technology.

[16]  M. Bäumer,et al.  The particle proximity effect: from model to high surface area fuel cell catalysts , 2014 .

[17]  Dimitrios G. Papageorgiou,et al.  Use of nanomaterials for the improvement of various industrial and biomedical applications. A review , 2012 .

[18]  Indranil Chowdhury,et al.  Mechanisms of TiO2 nanoparticle transport in porous media: role of solution chemistry, nanoparticle concentration, and flowrate. , 2011, Journal of colloid and interface science.

[19]  N. J. Themelis,et al.  Life cycle assessment of using powder and liquid precursors in plasma spraying: The case of yttria-stabilized zirconia , 2010 .

[20]  V. Bulović,et al.  High-efficiency quantum-dot light-emitting devices with enhanced charge injection , 2013, Nature Photonics.

[21]  Sverker Molander,et al.  Impacts of a Silver‐Coated Future , 2011 .

[22]  Sangwon Suh,et al.  The Role of Scale and Technology Maturity in Life Cycle Assessment of Emerging Technologies: A Case Study on Carbon Nanotubes , 2015 .

[23]  Rajive Dhingra,et al.  Sustainable Nanotechnology: Through Green Methods and Life-Cycle Thinking , 2010 .

[24]  S. Das,et al.  Green Synthesis of Nanomaterials with Special Reference to Environmental and Biomedical Applications , 2015 .

[25]  R. Bleher,et al.  Environmental release of core-shell semiconductor nanocrystals from free-standing polymer nanocomposite films. , 2016, Environmental science. Nano.

[26]  Helen H. Lou,et al.  Environmental Impact Assessment for Potential Continuous Processes for the Production of Carbon Nanotubes , 2008 .

[27]  Alexis Laurent,et al.  Analysis of current research addressing complementary use of life-cycle assessment and risk assessment for engineered nanomaterials: have lessons been learned from previous experience with chemicals? , 2012, Journal of Nanoparticle Research.

[28]  A. Cassandra,et al.  A Novel Method for the Synthesis of , 2005 .

[29]  A. Nazari,et al.  RETRACTED: The effects of TiO2 nanoparticles on properties of binary blended concrete , 2011 .

[30]  Alireza Kargar,et al.  Tandem structured spectrally selective coating layer of copper oxide nanowires combined with cobalt oxide nanoparticles , 2015 .

[31]  Navid B. Saleh,et al.  Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): implications for nanoparticle neurotoxicity. , 2006, Environmental science & technology.

[32]  ANNE KAHRU,et al.  Mapping the dawn of nanoecotoxicological research. , 2013, Accounts of chemical research.

[33]  Sangwon Suh,et al.  Life cycle assessment at nanoscale: review and recommendations , 2012, The International Journal of Life Cycle Assessment.

[34]  Fadri Gottschalk,et al.  The release of engineered nanomaterials to the environment. , 2011, Journal of environmental monitoring : JEM.

[35]  S. Schulte,et al.  Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: an in vitro and in vivo study. , 2011, Toxicological sciences : an official journal of the Society of Toxicology.

[36]  M. Conradi,et al.  NANOSILICA-REINFORCED POLYMER COMPOSITES , 2013 .

[37]  M. Mahmoud,et al.  Design of novel nano-sorbents based on nano-magnetic iron oxide–bound-nano-silicon oxide–immobilized-triethylenetetramine for implementation in water treatment of heavy metals , 2013 .

[38]  Paul Westerhoff,et al.  Nanoparticle silver released into water from commercially available sock fabrics. , 2008, Environmental science & technology.

[39]  Sven Bernesson,et al.  A limited LCA comparing large- and small-scale production of ethanol for heavy engines under Swedish conditions , 2006 .

[40]  T. Masunaga [Nanomaterials in cosmetics--present situation and future]. , 2014, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[41]  Roland Hischier,et al.  Life cycle assessment of engineered nanomaterials: state of the art and strategies to overcome existing gaps. , 2012, The Science of the total environment.

[42]  K. Kasemets,et al.  Toxicity of CuO nanoparticles to yeast Saccharomyces cerevisiae BY4741 wild-type and its nine isogenic single-gene deletion mutants. , 2013, Chemical research in toxicology.

[43]  Evan S. Michelson “The Train Has Left the Station”: The Project on Emerging Nanotechnologies and the Shaping of Nanotechnology Policy in the United States , 2013 .

[44]  Huiguang Zhu,et al.  Quantum dot weathering results in microbial toxicity. , 2008, Environmental science & technology.

[45]  Bernd Nowack,et al.  Nanosilver Revisited Downstream , 2010, Science.

[46]  Dasmawati Mohamad,et al.  Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism , 2015, Nano-Micro Letters.

[47]  V. Puntes,et al.  Reactivity of inorganic nanoparticles in biological environments: insights into nanotoxicity mechanisms , 2012 .

[48]  Mary Ann Curran,et al.  Life cycle assessment as a tool to enhance the environmental performance of carbon nanotube products: a review , 2012 .

[49]  S. Walker,et al.  Aggregate morphology of nano-TiO2: role of primary particle size, solution chemistry, and organic matter. , 2013, Environmental science. Processes & impacts.

[50]  M. Wiesner,et al.  Nanomaterials as possible contaminants: the fullerene example. , 2008, Water science and technology : a journal of the International Association on Water Pollution Research.

[51]  Clémence Disdier Evaluation of TiO2 exposure impact on adult and vulnerable brains , 2016 .

[52]  Michael Nentwich Nano and the environment - Part I: Potential environmental benefits and sustainability effects , 2012 .

[53]  Patrik Schmuki,et al.  TiO2 nanotubes: synthesis and applications. , 2011, Angewandte Chemie.

[54]  S. Hellweg,et al.  Prospective Environmental Life Cycle Assessment of Nanosilver T-Shirts , 2011, Environmental science & technology.

[55]  J. Lead,et al.  Transformations of nanomaterials in the environment. , 2012, Environmental science & technology.

[56]  Mark R. Wiesner,et al.  Estimating production data for five engineered nanomaterials as a basis for exposure assessment. , 2011, Environmental science & technology.

[57]  Yuhai Hu,et al.  Flexible rechargeable lithium ion batteries: advances and challenges in materials and process technologies , 2014 .

[58]  Vicki Stone,et al.  Toxicology of nanoparticles: A historical perspective , 2007 .

[59]  A. Brent,et al.  A South African research agenda to investigate the potential environmental, health and safety risks of nanotechnology , 2010 .

[60]  S. Molander,et al.  Life cycle assessment of wastewater systems : Influence of system boundaries and scale on calculated environmental loads , 2000 .

[61]  Nikhil Krishnan,et al.  A hybrid life cycle inventory of nano-scale semiconductor manufacturing. , 2008, Environmental science & technology.

[62]  Somchai Wongwises,et al.  Numerical investigation of effective parameters in convective heat transfer of nanofluids flowing under a laminar flow regime , 2011 .

[63]  R. Tilley,et al.  Nanomaterials: Earthworms lit with quantum dots. , 2013, Nature nanotechnology.

[64]  Jing Li,et al.  Toxicity and internalization of CuO nanoparticles to prokaryotic alga Microcystis aeruginosa as affected by dissolved organic matter. , 2011, Environmental science & technology.

[65]  Stefan Seeger,et al.  Industrial production quantities and uses of ten engineered nanomaterials in Europe and the world , 2012, Journal of Nanoparticle Research.

[66]  Thomas L. Theis,et al.  An environmental impact assessment of quantum dot photovoltaics (QDPV) from raw material acquisition through use , 2011 .

[67]  C. Plug Southern African science in the year 1909 - 100n , 2009 .

[68]  B. Bakshi,et al.  Life Cycle of Titanium Dioxide Nanoparticle Production , 2011 .

[69]  G Vecchio,et al.  In vivo assessment of CdSe-ZnS quantum dots: coating dependent bioaccumulation and genotoxicity. , 2012, Nanoscale.

[70]  G. Halvani,et al.  Adsorption of humic acid by amine-modified nanocellulose: an experimental and simulation study , 2014, International Journal of Environmental Science and Technology.

[71]  R. Scholz,et al.  Modeled environmental concentrations of engineered nanomaterials (TiO(2), ZnO, Ag, CNT, Fullerenes) for different regions. , 2009, Environmental science & technology.

[72]  David Rejeski,et al.  Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory , 2015, Beilstein journal of nanotechnology.

[73]  G. Ayoko,et al.  Engineered nanomaterials: knowledge gaps in fate, exposure, toxicity, and future directions , 2014 .

[74]  Teofil Jesionowski,et al.  Zinc Oxide—From Synthesis to Application: A Review , 2014, Materials.

[75]  Peng Zhang,et al.  Effect of Nano-SiO 2 Particles on Fracture Properties of Concrete Composite Containing Fly Ash , 2015 .

[76]  R. Sankar,et al.  Inhibition of pathogenic bacterial growth on excision wound by green synthesized copper oxide nanoparticles leads to accelerated wound healing activity in Wistar Albino rats , 2015, Journal of Materials Science: Materials in Medicine.

[77]  P. Bowen,et al.  Bioavailability of inorganic nanoparticles to planktonic bacteria and aquatic microalgae in freshwater , 2014 .

[78]  Bernd Nowack,et al.  120 years of nanosilver history: implications for policy makers. , 2011, Environmental science & technology.

[79]  Björn A. Sandén,et al.  Assessing the Environmental Risks of Silver from Clothes in an Urban Area , 2014 .

[80]  Björn A. Sandén,et al.  Energy Requirements of Carbon Nanoparticle Production , 2008 .

[81]  Vikas Khanna,et al.  Life Cycle Energy Consumption and Environmental Impact , 2008 .

[82]  M. Mortimer,et al.  Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review , 2013, Archives of Toxicology.

[83]  Xueya Wang,et al.  Intelligent nanomaterials for medicine: carrier platforms and targeting strategies in the context of clinical application. , 2013, Nanomedicine : nanotechnology, biology, and medicine.

[84]  Steffen Foss Hansen,et al.  Categorization framework to aid exposure assessment of nanomaterials in consumer products , 2008, Ecotoxicology.

[85]  Jianfeng Chen,et al.  Can graphene quantum dots cause DNA damage in cells? , 2015, Nanoscale.

[86]  C. Su,et al.  Release and toxicity comparison between industrial- and sunscreen-derived nano-ZnO particles , 2016, International Journal of Environmental Science and Technology.

[87]  I. Godínez,et al.  Aggregation and transport of nano-TiO2 in saturated porous media: effects of pH, surfactants and flow velocity. , 2011, Water research.

[88]  M. Rafatullah,et al.  Preparation of polyaniline based nanocomposite material and their environmental applications , 2015, International Journal of Environmental Science and Technology.

[89]  M. Shariat,et al.  A novel method for synthesis of nano-γ-Al2O3: study of adsorption behavior of chromium, nickel, cadmium and lead ions , 2015, International Journal of Environmental Science and Technology.

[90]  Anders Baun,et al.  NanoRiskCat – a conceptual decision support tool for nanomaterials , 2011 .

[91]  Jean-François Gaillard,et al.  Cytotoxicity of commercial nano-TiO2 to Escherichia coli assessed by high-throughput screening: effects of environmental factors. , 2013, Water research.

[92]  M A Kiser,et al.  Titanium nanomaterial removal and release from wastewater treatment plants. , 2009, Environmental science & technology.

[93]  Benjamin Gilbert,et al.  Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. , 2008, ACS nano.

[94]  Michael A. Gonzalez,et al.  An examination of silver nanoparticles in socks using screening-level life cycle assessment , 2011 .

[95]  Lutz Mädler,et al.  Stability, bioavailability, and bacterial toxicity of ZnO and iron-doped ZnO nanoparticles in aquatic media. , 2011, Environmental science & technology.

[96]  Duncan Kushnir Foresight and Feedback: Monitoring and assessing the environmental implications of emerging technologies , 2012 .

[97]  Mauro Ferrari,et al.  Mesoporous silica as a membrane for ultra-thin implantable direct glucose fuel cells. , 2011, Lab on a chip.