DNA-Origami-Based Assembly of Anisotropic Plasmonic Gold Nanostructures.

Precise control over the assembly of anisotropic plasmonic gold nanostructures with relative spatial directionality and sequence asymmetry remains a major challenge and offers great fundamental insight and optical application possibilities. Here, a novel strategy is developed to anisotropically functionalize gold nanorods (AuNRs) by using a DNA-origami-based precise machine to transfer essential DNA sequence configurations to the surface of the AuNRs through an intentionally designed toehold-initiated displacement reaction. Different AuNR products are examined via hybridization with DNA-AuNPs that display distinct elements of regiospecificity. These assembled anisotropic plasmonic gold nanostructures based on the DNA-origami precise machine inherit the encoded information from the parent platform with high fidelity and show fixed orientation and bonding anisotropy, thereby generating discrete plasmonic nanostructures with enhanced Raman resonance.

[1]  Tao Zhang,et al.  Chiral plasmonic DNA nanostructures with switchable circular dichroism , 2013, Nature Communications.

[2]  Yi Lu,et al.  Facile and efficient preparation of anisotropic DNA-functionalized gold nanoparticles and their regioselective assembly. , 2013, Journal of the American Chemical Society.

[3]  Chad A Mirkin,et al.  Asymmetric functionalization of gold nanoparticles with oligonucleotides. , 2006, Journal of the American Chemical Society.

[4]  Liguang Xu,et al.  Regiospecific plasmonic assemblies for in situ Raman spectroscopy in live cells. , 2012, Journal of the American Chemical Society.

[5]  Alaaldin M. Alkilany,et al.  The gold standard: gold nanoparticle libraries to understand the nano-bio interface. , 2013, Accounts of chemical research.

[6]  J. Storhoff,et al.  A DNA-based method for rationally assembling nanoparticles into macroscopic materials , 1996, Nature.

[7]  Faisal A. Aldaye,et al.  Loading and selective release of cargo in DNA nanotubes with longitudinal variation. , 2010, Nature chemistry.

[8]  Lisa V. Poulikakos,et al.  Ultraviolet Plasmonic Chirality from Colloidal Aluminum Nanoparticles Exhibiting Charge‐Selective Protein Detection , 2015, Advanced materials.

[9]  Wenchuan Wang,et al.  Systematic Tuning and Multifunctionalization of Covalent Organic Polymers for Enhanced Carbon Capture. , 2015, Journal of the American Chemical Society.

[10]  Shawn M. Douglas,et al.  Self-assembly of DNA into nanoscale three-dimensional shapes , 2009, Nature.

[11]  P. Rothemund.  Folding DNA to create nanoscale shapes and patterns , 2006, Nature.

[12]  Nader Engheta,et al.  Circuits with Light at Nanoscales: Optical Nanocircuits Inspired by Metamaterials , 2007, Science.

[13]  Chunhai Fan,et al.  A DNA-Origami chip platform for label-free SNP genotyping using toehold-mediated strand displacement. , 2010, Small.

[14]  C. Mao,et al.  Self-assembly of molecule-like nanoparticle clusters directed by DNA nanocages. , 2015, Journal of the American Chemical Society.

[15]  F. Simmel,et al.  DNA-based self-assembly of chiral plasmonic nanostructures with tailored optical response , 2011, Nature.

[16]  Yonggang Ke,et al.  Site-Specific Surface Functionalization of Gold Nanorods Using DNA Origami Clamps. , 2016, Journal of the American Chemical Society.

[17]  Weihai Ni,et al.  Strong Chiroptical Activities in Gold Nanorod Dimers Assembled Using DNA Origami Templates , 2015 .

[18]  Zhilin Yang,et al.  Sub-5 nm nanobowl gaps electrochemically templated by SiO2-coated Au nanoparticles as surface-enhanced Raman scattering hot spots. , 2014, Chemical communications.

[19]  Yonggang Ke,et al.  Au nanorod helical superstructures with designed chirality. , 2015, Journal of the American Chemical Society.

[20]  Jie Chao,et al.  Transfer of Two-Dimensional Oligonucleotide Patterns onto Stereocontrolled Plasmonic Nanostructures through DNA-Origami-Based Nanoimprinting Lithography. , 2016, Angewandte Chemie.

[21]  Kevin Marsh,et al.  Erratum: Corrigendum: The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody , 2013 .

[22]  Stanislav Emelianov,et al.  Multiwavelength photoacoustic imaging and plasmon resonance coupling of gold nanoparticles for selective detection of cancer. , 2009, Nano letters.

[23]  Erik Winfree,et al.  Self-assembly of carbon nanotubes into two-dimensional geometries using DNA origami templates. , 2010, Nature nanotechnology.

[24]  N. Kotov,et al.  Unexpected chirality of nanoparticle dimers and ultrasensitive chiroplasmonic bioanalysis. , 2013, Journal of the American Chemical Society.

[25]  Jie Chao,et al.  DNA-based plasmonic nanostructures , 2015 .

[26]  P. Schultz,et al.  Organization of 'nanocrystal molecules' using DNA , 1996, Nature.

[27]  Stefan Diez,et al.  Toward Self-Assembled Plasmonic Devices: High-Yield Arrangement of Gold Nanoparticles on DNA Origami Templates. , 2016, ACS nano.

[28]  Suchetan Pal,et al.  Dynamic tuning of DNA-nanoparticle superlattices by molecular intercalation of double helix. , 2015, Journal of the American Chemical Society.

[29]  Jennifer N Cha,et al.  Large-area spatially ordered arrays of gold nanoparticles directed by lithographically confined DNA origami. , 2010, Nature nanotechnology.

[30]  N. Seeman.  DNA in a material world , 2003, Nature.

[31]  H. Sleiman,et al.  Transfer of molecular recognition information from DNA nanostructures to gold nanoparticles , 2016, Nature Chemistry.