A Novel Approach to Antigen-Specific Deletion of CTL with Minimal Cellular Activation Using a 3 Domain Mutants of MHC Class I / Peptide Complex express

[1]  J. Bell,et al.  Reconstitution of antigen presentation in HLA class I‐negative cancer cells with peptide‐β2m fusion molecules , 2001, European journal of immunology.

[2]  Douglas D. Richman,et al.  HIV-Specific Cd8+ T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function , 2000, The Journal of experimental medicine.

[3]  D. Price,et al.  Specificity of CTL interactions with peptide-MHC class I tetrameric complexes is temperature dependent. , 1999, Journal of immunology.

[4]  J. Daley,et al.  Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death. , 1999, Science.

[5]  S. L. Silins,et al.  The influence of antiviral T-cell responses on the alloreactive repertoire. , 1999, Immunology today.

[6]  S. Rowland-Jones,et al.  Rapid death of adoptively transferred T cells in acquired immunodeficiency syndrome. , 1999, Blood.

[7]  D. Green,et al.  Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells. , 1998, Immunity.

[8]  J. Altman,et al.  Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]. , 1998, Immunity.

[9]  P. Allen,et al.  Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation. , 1998, Science.

[10]  P. Klenerman,et al.  Copresentation of natural HIV-1 agonist and antagonist ligands fails to induce the T cell receptor signaling cascade. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[11]  A. Abbas,et al.  Homeostasis and self-tolerance in the immune system: turning lymphocytes off. , 1998, Science.

[12]  G. Ogg,et al.  Direct isolation, phenotyping and cloning of low-frequency antigen-specific cytotoxic T lymphocytes from peripheral blood , 1998, Current Biology.

[13]  R. Germain,et al.  Selective Induction of Apoptosis in Mature T Lymphocytes by Variant T Cell Receptor Ligands , 1998, The Journal of experimental medicine.

[14]  P. M. Davis,et al.  Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation. , 1997, Journal of immunology.

[15]  Philip J. R. Goulder,et al.  Phenotypic Analysis of Antigen-Specific T Lymphocytes , 1996, Science.

[16]  G. Koretzky,et al.  Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. , 1996, Blood.

[17]  Warren Strober,et al.  Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome , 1995, Cell.

[18]  Seamus J. Martin,et al.  Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas , 1995, Nature.

[19]  P. Romero,et al.  CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes , 1995, Nature.

[20]  A. Gaur,et al.  Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. , 1992, Science.

[21]  P. Matzinger.  The JAM test. A simple assay for DNA fragmentation and cell death. , 1991, Journal of immunological methods.

[22]  R. Siegel,et al.  Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment. , 1999, Annual review of immunology.