Design and synthesis of benzo-lipoxin A4 analogs with enhanced stability and potent anti-inflammatory properties.
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C. Serhan | Raquel Keledjian | Rong Yang | N. Petasis | Eric Tjonahen | Yee-Ping Sun | Kalyan C Nagulapalli
[1] M. Perretti,et al. Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities. , 2007, Journal of medicinal chemistry.
[2] C. Serhan. Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. , 2007, Annual review of immunology.
[3] Jennifer E. Golden,et al. Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents. , 2006, Bioorganic & medicinal chemistry letters.
[4] John Savill,et al. Resolution of inflammation: the beginning programs the end , 2005, Nature Immunology.
[5] J. Wallace,et al. Lipoxins in gastric mucosal health & disease , 2005 .
[6] J. Uddin,et al. Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[7] J. Parkinson,et al. Second-generation beta-oxidation resistant 3-oxa-lipoxin A4 analogs. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[8] B. Levy. Lipoxins and lipoxin analogs in asthma. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[9] A. Kantarcı,et al. Lipoxin signaling in neutrophils and their role in periodontal disease. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[10] K. Gronert. Lipoxins in the eye and their role in wound healing. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[11] S. Sodin-Semrl,et al. Lipoxin A4 biology in the human synovium. Role of the ALX signaling pathways in modulation of inflammatory arthritis. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[12] J. Uddin,et al. Cystic fibrosis and lipoxins. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[13] C. Serhan. Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[14] D. Gilroy,et al. The role of aspirin-triggered lipoxins in the mechanism of action of aspirin. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[15] C. Serhan,et al. Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[16] J. Parkinson,et al. A beta-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[17] P. Ridker,et al. Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[18] C. Serhan,et al. Lipoxins and novel 15‐epi‐lipoxin analogs display potent anti‐inflammatory actions after oral administration , 2004, British journal of pharmacology.
[19] Adriano G. Rossi,et al. Inflammatory Resolution: new opportunities for drug discovery , 2004, Nature Reviews Drug Discovery.
[20] C. Godson,et al. Lipoxins: potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease. , 2004, Kidney international.
[21] J. Uddin,et al. Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway , 2004, Nature Immunology.
[22] A. Schottelius,et al. Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo. , 2004, Journal of medicinal chemistry.
[23] C. Clish,et al. Reduced Inflammation and Tissue Damage in Transgenic Rabbits Overexpressing 15-Lipoxygenase and Endogenous Anti-inflammatory Lipid Mediators 1 , 2003, The Journal of Immunology.
[24] C. Serhan,et al. Aspirin-Triggered Lipoxin A4 and B4 Analogs Block Extracellular Signal-Regulated Kinase-Dependent TNF-α Secretion from Human T Cells 1 , 2003, The Journal of Immunology.
[25] Christophe Dugave,et al. Cis-trans isomerization of organic molecules and biomolecules: implications and applications. , 2003, Chemical reviews.
[26] C. Serhan,et al. Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells , 2003, The Journal of Biological Chemistry.
[27] R. Flower. The development of COX2 inhibitors , 2003, Nature Reviews Drug Discovery.
[28] K. Asadullah,et al. An Aspirin-Triggered Lipoxin A4 Stable Analog Displays a Unique Topical Anti-Inflammatory Profile , 2002, The Journal of Immunology.
[29] Sambasivarao Kotha,et al. Recent applications of the Suzuki–Miyaura cross-coupling reaction in organic synthesis , 2002 .
[30] T. Lawrence,et al. Anti-inflammatory lipid mediators and insights into the resolution of inflammation , 2002, Nature Reviews Immunology.
[31] Eugene Y. Kim,et al. Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4 , 2002, Nature Medicine.
[32] C. Serhan. Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: an update and role in anti-inflammation and pro-resolution. , 2002, Prostaglandins & other lipid mediators.
[33] A. Young,et al. Lipoxin A4 Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis1 , 2002, The Journal of Immunology.
[34] O. Levy,et al. Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[35] C. Funk,et al. Prostaglandins and leukotrienes: advances in eicosanoid biology. , 2001, Science.
[36] A. Mori,et al. Mizoroki-Heck type reaction of organoboron reagents with alkenes and alkynes. A Pd(II)-catalyzed pathway with Cu(OAc)2 as an oxidant. , 2001, Organic letters.
[37] P. Macmathuna,et al. Lipoxin A4 and Aspirin-Triggered 15-Epi-Lipoxin A4 Antagonize TNF-α-Stimulated Neutrophil-Enterocyte Interactions In Vitro and Attenuate TNF-α-Induced Chemokine Release and Colonocyte Apoptosis in Human Intestinal Mucosa Ex Vivo1 , 2001, The Journal of Immunology.
[38] B. Levy,et al. Oxidoreductases in Lipoxin A4 Metabolic Inactivation , 2000, The Journal of Biological Chemistry.
[39] C. Clish,et al. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo , 1999 .
[40] S. Kurozumi,et al. Palladium-catalyzed coupling reactions of bromobenzaldehydes with 3,4-di(tert-butyldimethylsilyloxy)-1-alkene to (3,4-dihydroxyalkenyl)benzaldehydes in the synthesis of lipoxin analogues , 1998 .
[41] C. Clish,et al. Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues. , 1998, The Journal of clinical investigation.
[42] T. Takano,et al. Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors , 1997, The Journal of experimental medicine.
[43] T. Jeffery. ON THE EFFICIENCY OF TETRAALKYLAMMONIUM SALTS IN HECK TYPE REACTIONS , 1996 .
[44] N. Petasis,et al. Mild conversion of alkenyl boronic acids to alkenyl halides with halosuccinimides , 1996 .
[45] I. Akritopoulou‐Zanze,et al. Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils. , 1995, Biochemistry.
[46] N. Miyaura,et al. Palladium(0)-Catalyzed Cross-Coupling Reaction of Alkoxydiboron with Haloarenes: A Direct Procedure for Arylboronic Esters , 1995 .
[47] Norio Miyaura,et al. Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds , 1995 .
[48] C. Serhan,et al. Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[49] C. Serhan,et al. Lipoxin A4 metabolism by differentiated HL-60 cells and human monocytes: conversion to novel 15-oxo and dihydro products. , 1993, Biochemistry.
[50] N. Petasis,et al. Titanium-mediated carbonyl olefinations. 1. Methylenations of carbonyl compounds with dimethyltitanocene , 1990 .
[51] R. Soundararajan,et al. Hydroboration with boron halides and trialkylsilanes , 1990 .
[52] S. Dahlén,et al. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. , 1987, Science.
[53] K. Takai,et al. Simple and selective method for RCHO → (E)-RCH=CHX conversion by means of a CHX3-CrCl2 system , 1986 .