Endochondral ossification signals in cartilage degradation during osteoarthritis progression in experimental mouse models.
暂无分享,去创建一个
[1] T. Wakayama,et al. Skeletal malformations caused by the Dh (Dominant hemimelia) gene in mice. , 1996, Experimental animals.
[2] Kozo Nakamura,et al. Carminerin contributes to chondrocyte calcification during endochondral ossification , 2006, Nature Medicine.
[3] Kozo Nakamura,et al. Association of microsomal prostaglandin E synthase 1 deficiency with impaired fracture healing, but not with bone loss or osteoarthritis, in mouse models of skeletal disorders. , 2008, Arthritis and rheumatism.
[4] S. Glasson,et al. The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse. , 2007, Osteoarthritis and cartilage.
[5] Gillian Murphy,et al. Structure and function of matrix metalloproteinases and TIMPs. , 2006, Cardiovascular research.
[6] G. Nuki,et al. Experimentally-induced osteoarthritis in the dog. , 1973, Annals of the rheumatic diseases.
[7] C. Little,et al. Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair. , 2007, The Journal of clinical investigation.
[8] Kozo Nakamura,et al. Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. , 2006, Arthritis and rheumatism.
[9] W. Richter,et al. Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading , 2004, Arthritis research & therapy.
[10] Kozo Nakamura,et al. Cystatin 10, a Novel Chondrocyte-specific Protein, May Promote the Last Steps of the Chondrocyte Differentiation Pathway* , 2003, Journal of Biological Chemistry.
[11] D. D’Lima,et al. Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis. , 2006, Arthritis and rheumatism.
[12] K. Nakamura,et al. Involvement of fibroblast growth factor-2 in joint destruction of rheumatoid arthritis patients. , 1999, Rheumatology.
[13] Y. Yoo,et al. TRAIL induces apoptosis of chondrocytes and influences the pathogenesis of experimentally induced rat osteoarthritis. , 2004, Arthritis and rheumatism.
[14] Y. Figenschau,et al. Tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in human articular chondrocytes in vitro. , 2002, Biochemical and biophysical research communications.
[15] M. Chung,et al. Regional quantification of cartilage type II collagen and aggrecan messenger RNA in joints with early experimental osteoarthritis. , 2002, Arthritis and rheumatism.
[16] C. Brinckerhoff,et al. Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors , 2001, Arthritis Research & Therapy.
[17] R. Mason,et al. Gene deletion of either interleukin-1beta, interleukin-1beta-converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy. , 2003, Arthritis and rheumatism.
[18] J. Jordan,et al. Epidemiology of osteoarthritis. , 2010, Clinics in geriatric medicine.
[19] B. Olsen,et al. Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis. , 2007, Arthritis and rheumatism.
[20] C. Brinckerhoff,et al. Molecular targets in osteoarthritis: metalloproteinases and their inhibitors. , 2007, Current drug targets.
[21] S. Miyamoto,et al. Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis , 2004, Arthritis research & therapy.
[22] T. Muneta,et al. Prevention of cartilage destruction with intraarticular osteoclastogenesis inhibitory factor/osteoprotegerin in a murine model of osteoarthritis. , 2007, Arthritis and rheumatism.
[23] F. Berenbaum,et al. Cyclooxygenase activity in chondrocytes from osteoarthritic and healthy cartilage. , 1999, Revue du rhumatisme.
[24] E. Vignon,et al. Differential gene expression analysis in a rabbit model of osteoarthritis induced by anterior cruciate ligament (ACL) section. , 2002, Biorheology.
[25] L. Duong,et al. The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. , 2004, Arthritis and rheumatism.
[26] A. Fourie,et al. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro , 2005, Nature.
[27] H. Inoue,et al. Epidemiology of Osteoarthritis of the Knee , 1995 .
[28] B. Olsen,et al. Lessons from genetic forms of osteoarthritis for the pathogenesis of the disease. , 2007, Osteoarthritis and cartilage.
[29] N. Boos,et al. Immunohistochemical Analysis of Type X-Collagen Expression in Osteoarthritis of the Hip Joint , 2000 .
[30] E. Vignon,et al. Assessment of specific mRNA levels in cartilage regions in a lapine model of osteoarthritis , 2002, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[31] B. Olsen,et al. Activation of the Discoidin Domain Receptor 2 Induces Expression of Matrix Metalloproteinase 13 Associated with Osteoarthritis in Mice*♦ , 2005, Journal of Biological Chemistry.
[32] D. D’Lima,et al. Cell death in cartilage. , 2004, Osteoarthritis and cartilage.
[33] N. Kanatani,et al. Skeletal Malformations Caused by Overexpression of Cbfa1 or Its Dominant Negative Form in Chondrocytes , 2001, The Journal of cell biology.
[34] Kozo Nakamura,et al. Osteoarthritis development in novel experimental mouse models induced by knee joint instability. , 2005, Osteoarthritis and cartilage.
[35] J. Matyas,et al. The early molecular natural history of experimental osteoarthritis. I. Progressive discoordinate expression of aggrecan and type II procollagen messenger RNA in the articular cartilage of adult animals. , 1999, Arthritis and rheumatism.
[36] Yusuke Nakamura,et al. Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine , 1998, Nature Genetics.
[37] S. Glasson. In vivo osteoarthritis target validation utilizing genetically-modified mice. , 2007, Current drug targets.
[38] S. Takeda,et al. Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. , 2001, Genes & development.
[39] K. von der Mark,et al. Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophy. , 1992, Arthritis and rheumatism.
[40] C. López-Otín,et al. Collagenase 3 Is a Target of Cbfa1, a Transcription Factor of the runt Gene Family Involved in Bone Formation , 1999, Molecular and Cellular Biology.