Catalytic Strand Separation by RECQ1 Is Required for RPA-Mediated Response to Replication Stress

[1]  Yuntao Xie,et al.  Mutations in RECQL Gene Are Associated with Predisposition to Breast Cancer , 2015, PLoS genetics.

[2]  Aniruddh Kashyap,et al.  Germline RECQL mutations are associated with breast cancer susceptibility , 2015, Nature Genetics.

[3]  F. von Delft,et al.  Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures , 2015, Proceedings of the National Academy of Sciences.

[4]  S. Butcher,et al.  Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases , 2015, Proceedings of the National Academy of Sciences.

[5]  Raquel Herrador,et al.  Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells , 2015, The Journal of cell biology.

[6]  Sudha Sharma An appraisal of RECQ1 expression in cancer progression , 2014, Front. Genet..

[7]  P. Meltzer,et al.  Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion , 2014, Cell cycle.

[8]  Xiaoping Zhang,et al.  RECQL1 Plays an Important Role in the Development of Tongue Squamous Cell Carcinoma , 2014, Cellular Physiology and Biochemistry.

[9]  D. Kyriakidis,et al.  Tumor suppressor PTEN in breast cancer: heterozygosity, mutations and protein expression. , 2014, Anticancer research.

[10]  N. Mailand,et al.  ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA , 2013, Cell.

[11]  HK Fam Delineating the effects BRCA1 and BRCA2 loss of heterozygosity in pancreatic cancer progression , 2014, Clinical genetics.

[12]  K. Ushijima,et al.  RECQL1 DNA Repair Helicase: A Potential Therapeutic Target and a Proliferative Marker against Ovarian Cancer , 2013, PloS one.

[13]  R. Brosh DNA helicases involved in DNA repair and their roles in cancer , 2013, Nature Reviews Cancer.

[14]  A. Lal,et al.  Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D , 2013, Molecular Cancer.

[15]  R. Brosh,et al.  Disease-causing missense mutations in human DNA helicase disorders. , 2013, Mutation research.

[16]  J. Diffley,et al.  Controlling DNA replication origins in response to DNA damage – inhibit globally, activate locally , 2013, Journal of Cell Science.

[17]  M. Lopes,et al.  Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition , 2013, Nature Structural &Molecular Biology.

[18]  M. Jasin,et al.  RECQ1 plays a distinct role in cellular response to oxidative DNA damage. , 2012, DNA repair.

[19]  Benjamin D. Yu,et al.  Modifier Genes and the Plasticity of Genetic Networks in Mice , 2012, PLoS genetics.

[20]  S. Bonin,et al.  The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation , 2011, Molecular Cancer.

[21]  M. Mizoguchi,et al.  Loss of heterozygosity analysis in malignant gliomas , 2011, Brain Tumor Pathology.

[22]  O. Fernandez-Capetillo,et al.  The ATR barrier to replication-born DNA damage. , 2010, DNA repair.

[23]  O. Gileadi,et al.  A prominent β-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation , 2010, Nucleic acids research.

[24]  Y. Furuichi,et al.  RecQL1 DNA repair helicase: A potential tumor marker and therapeutic target against hepatocellular carcinoma. , 2010, International journal of molecular medicine.

[25]  R. Monnat,et al.  Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation , 2010, Molecular and Cellular Biology.

[26]  J. Dumont,et al.  Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ. , 2009, Endocrine-related cancer.

[27]  S. Costantini,et al.  Structure of the human RECQ1 helicase reveals a putative strand-separation pin , 2009, Proceedings of the National Academy of Sciences.

[28]  R. Brosh,et al.  RECQ1 Possesses DNA Branch Migration Activity* , 2008, Journal of Biological Chemistry.

[29]  R. Brosh,et al.  Human RECQ1 Is a DNA Damage Responsive Protein Required for Genotoxic Stress Resistance and Suppression of Sister Chromatid Exchanges , 2007, PloS one.

[30]  A. Patwardhan,et al.  Different Quaternary Structures of Human RECQ1 Are Associated with Its Dual Enzymatic Activity , 2007, PLoS biology.

[31]  D. Stumpo,et al.  RECQL, a Member of the RecQ Family of DNA Helicases, Suppresses Chromosomal Instability , 2006, Molecular and Cellular Biology.

[32]  Manal M. Hassan,et al.  Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival. , 2006, Cancer research.

[33]  J. Keck,et al.  Coupling DNA-binding and ATP hydrolysis in Escherichia coli RecQ: role of a highly conserved aromatic-rich sequence , 2005, Nucleic acids research.

[34]  T. Helleday,et al.  Spontaneous Homologous Recombination Is Induced by Collapsed Replication Forks That Are Caused by Endogenous DNA Single-Strand Breaks , 2005, Molecular and Cellular Biology.

[35]  A. Vindigni,et al.  Biochemical Analysis of the DNA Unwinding and Strand Annealing Activities Catalyzed by Human RECQ1*[boxs] , 2005, Journal of Biological Chemistry.

[36]  K. Doherty,et al.  Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A. , 2004, Nucleic acids research.

[37]  K. Kohn,et al.  Repair of and checkpoint response to topoisomerase I-mediated DNA damage. , 2003, Mutation research.

[38]  J. Keck,et al.  High‐resolution structure of the E.coli RecQ helicase catalytic core , 2003, The EMBO journal.

[39]  N. Ellis,et al.  Differential regulation of human RecQ family helicases in cell transformation and cell cycle , 2000, Oncogene.

[40]  P. D'Arpa,et al.  Mechanism of Action of Camptothecin , 1996, Annals of the New York Academy of Sciences.

[41]  T. Shows,et al.  Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue. , 1995, Genomics.

[42]  P. Blackshear,et al.  Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ. , 1994, The Journal of biological chemistry.

[43]  J. Yanagisawa,et al.  Purification of two DNA-dependent adenosinetriphosphatases having DNA helicase activity from HeLa cells and comparison of the properties of the two enzymes. , 1994, Journal of biochemistry.

[44]  新井 啓仁 RECQL1 and WRN proteins are potential therapeutic targets in head and neck squamous cell carcinoma , 2012 .