Pharmacological control of angiogenesis by regulating phosphorylation of myosin light chain 2.

[1]  Xiping Luo,et al.  MYL9 promotes squamous cervical cancer migration and invasion by enhancing aerobic glycolysis , 2023, The Journal of international medical research.

[2]  Kiyomi Tsuji-Tamura,et al.  FOXO1 promotes endothelial cell elongation and angiogenesis by up-regulating the phosphorylation of myosin light chain 2 , 2023, Angiogenesis.

[3]  D. Fraidenburg,et al.  Non-Muscle MLCK Contributes to Endothelial Cell Hyper-Proliferation through the ERK Pathway as a Mechanism for Vascular Remodeling in Pulmonary Hypertension , 2022, International journal of molecular sciences.

[4]  Kiyomi Tsuji-Tamura,et al.  Basic fibroblast growth factor uniquely stimulates quiescent vascular smooth muscle cells and induces proliferation and dedifferentiation , 2022, FEBS letters.

[5]  M. Feng,et al.  Myosin light chain 9 promotes the proliferation, invasion, migration and angiogenesis of colorectal cancer cells by binding to Yes-associated protein 1 and regulating Hippo signaling , 2022, Bioengineered.

[6]  H. Eguchi,et al.  Clinicopathological significance of MYL9 expression in pancreatic ductal adenocarcinoma , 2021, Cancer reports.

[7]  Kiyomi Tsuji-Tamura,et al.  TAGLN, a canonical marker of smooth muscle cells, is present in endothelial cells and involved in angiogenesis. , 2021, Journal of cell science.

[8]  Mwango Bwalya,et al.  Anti-angiogenesis in cancer therapeutics: the magic bullet , 2021, Journal of the Egyptian National Cancer Institute.

[9]  Kiyomi Tsuji-Tamura,et al.  The role of PI3K/Akt/mTOR signaling in dose-dependent biphasic effects of glycine on vascular development. , 2020, Biochemical and biophysical research communications.

[10]  W. Rasband,et al.  Angiogenesis Analyzer for ImageJ — A comparative morphometric analysis of “Endothelial Tube Formation Assay” and “Fibrin Bead Assay” , 2020, Scientific Reports.

[11]  Kiyomi Tsuji-Tamura,et al.  Glycine exerts dose-dependent biphasic effects on vascular development of zebrafish embryos. , 2020, Biochemical and biophysical research communications.

[12]  D. Mukherji,et al.  Resistance Mechanisms to Anti-angiogenic Therapies in Cancer , 2020, Frontiers in Oncology.

[13]  Jie Weng,et al.  Advanced glycation end products induce immature angiogenesis in in vivo and ex vivo mouse models. , 2020, American journal of physiology. Heart and circulatory physiology.

[14]  Le Ma,et al.  MicroRNA‐92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway , 2019, Journal of cellular and molecular medicine.

[15]  Kiyomi Tsuji-Tamura,et al.  Morphology regulation in vascular endothelial cells , 2018, Inflammation and Regeneration.

[16]  R. Boon,et al.  Endothelial Cell Metabolism in Atherosclerosis , 2018, Front. Cell Dev. Biol..

[17]  Kiyomi Tsuji-Tamura,et al.  Dual inhibition of mTORC1 and mTORC2 perturbs cytoskeletal organization and impairs endothelial cell elongation. , 2018, Biochemical and biophysical research communications.

[18]  L. Du,et al.  Rho‐kinase inhibitor Y‐27632 facilitates the proliferation, migration and pluripotency of human periodontal ligament stem cells , 2017, Journal of cellular and molecular medicine.

[19]  Guixue Wang,et al.  Cytotoxic effects of docetaxel as a candidate drug of drug-eluting stent on human umbilical vein endothelial cells and the signaling pathway of cell migration inhibition, adhesion delay and shape change , 2017, Regenerative biomaterials.

[20]  B. Kalyanaraman Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism , 2017, Redox biology.

[21]  T. Braunbeck,et al.  Size does matter - Determination of the critical molecular size for the uptake of chemicals across the chorion of zebrafish (Danio rerio) embryos. , 2017, Aquatic toxicology.

[22]  Toshio Kitazawa,et al.  Diversity and plasticity in signaling pathways that regulate smooth muscle responsiveness: Paradigms and paradoxes for the myosin phosphatase, the master regulator of smooth muscle contraction , 2017, Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.

[23]  Aleksander S. Popel,et al.  Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis , 2016, Scientific Reports.

[24]  Claus Bendtsen,et al.  Kinase Inhibition Leads to Hormesis in a Dual Phosphorylation-Dephosphorylation Cycle , 2016, PLoS Comput. Biol..

[25]  C. Heisenberg,et al.  Actin Rings of Power. , 2016, Developmental cell.

[26]  Benoit Ladoux,et al.  Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues. , 2016, Trends in cell biology.

[27]  Kiyomi Tsuji-Tamura,et al.  Inhibition of the PI3K–Akt and mTORC1 signaling pathways promotes the elongation of vascular endothelial cells , 2016, Journal of Cell Science.

[28]  Q. Wang,et al.  Role of Moesin in Advanced Glycation End Products-Induced Angiogenesis of Human Umbilical Vein Endothelial Cells , 2016, Scientific Reports.

[29]  Hongbo Liu,et al.  ROCK inhibitor Y-27632 inhibits the growth, migration, and invasion of Tca8113 and CAL-27 cells in tongue squamous cell carcinoma , 2016, Tumor Biology.

[30]  V. Muzykantov,et al.  Biomimetic channel modeling local vascular dynamics of pro-inflammatory endothelial changes. , 2016, Biomicrofluidics.

[31]  Mikaël M. Martino,et al.  Extracellular Matrix and Growth Factor Engineering for Controlled Angiogenesis in Regenerative Medicine , 2015, Front. Bioeng. Biotechnol..

[32]  Rui Cheng,et al.  Angiogenesis in diabetes and obesity , 2015, Reviews in Endocrine and Metabolic Disorders.

[33]  A. Miyawaki,et al.  Visualizing the cell-cycle progression of endothelial cells in zebrafish. , 2014, Developmental biology.

[34]  O. Kallioniemi,et al.  High-Throughput 3D Screening Reveals Differences in Drug Sensitivities between Culture Models of JIMT1 Breast Cancer Cells , 2013, PloS one.

[35]  I. Jacobs,et al.  In vitro three-dimensional modeling of fallopian tube secretory epithelial cells , 2013, BMC Cell Biology.

[36]  D. Ichikawa,et al.  HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells. , 2013, International journal of oncology.

[37]  Pekka Lappalainen,et al.  Actin stress fibers – assembly, dynamics and biological roles , 2012, Journal of Cell Science.

[38]  Thomas Lecuit,et al.  Biomechanical regulation of contractility: spatial control and dynamics. , 2012, Trends in cell biology.

[39]  Ann L. Miller The contractile ring , 2011, Current Biology.

[40]  B. Suki,et al.  Microtubule Dynamics Regulate Cyclic Stretch-Induced Cell Alignment in Human Airway Smooth Muscle Cells , 2011, PloS one.

[41]  Kiyomi Tsuji-Tamura,et al.  ES Cell Differentiation as a Model to Study Cell Biological Regulation of Vascular Development , 2011 .

[42]  M. Young,et al.  Interrelationship between protein phosphatase 1 and TGF-{beta} in regulating motility and cytoskeletal architecture of endothelial cells. , 2010, Anticancer research.

[43]  A. Ewald,et al.  Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration. , 2010, Developmental biology.

[44]  Song-Cheol Kim,et al.  The Synergistic Effect of Tautomycetin on Cyclosporine A-Mediated Immunosuppression in a Rodent Islet Allograft Model , 2010, Molecular medicine.

[45]  T. Furuyama,et al.  Foxo1 is essential for in vitro vascular formation from embryonic stem cells. , 2009, Biochemical and biophysical research communications.

[46]  Miguel Vicente-Manzanares,et al.  Non-muscle myosin II takes centre stage in cell adhesion and migration , 2009, Nature Reviews Molecular Cell Biology.

[47]  E. Dejana,et al.  VE-Cadherin-Mediated Cell-Cell Interaction Suppresses Sprouting via Signaling to MLC2 Phosphorylation , 2009, Current Biology.

[48]  Young-Sun Kim,et al.  Okadaic acid promotes angiogenesis via activation of hypoxia-inducible factor-1. , 2009, Cancer letters.

[49]  Hang Zhang,et al.  Myosin light-chain kinase contributes to the proliferation and migration of breast cancer cells through cross-talk with activated ERK1/2. , 2008, Cancer letters.

[50]  Kazuhiro Takahashi,et al.  Fasudil inhibits vascular endothelial growth factor–induced angiogenesis in vitro and in vivo , 2007, Molecular Cancer Therapeutics.

[51]  M. Chiquet,et al.  Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain. , 2006, Experimental cell research.

[52]  M. Bailly,et al.  Actin at cell-cell junctions is composed of two dynamic and functional populations , 2005, Journal of Cell Science.

[53]  H. Augustin,et al.  Expression of Angiopoietin-2 in Endothelial Cells Is Controlled by Positive and Negative Regulatory Promoter Elements , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[54]  S. Nishikawa,et al.  Abnormal Angiogenesis in Foxo1 (Fkhr)-deficient Mice* , 2004, Journal of Biological Chemistry.

[55]  M. Tamura,et al.  Periodontal ligament cells under intermittent tensile stress regulate mRNA expression of osteoprotegerin and tissue inhibitor of matrix metalloprotease-1 and -2 , 2004, Journal of Bone and Mineral Metabolism.

[56]  B. Weinstein,et al.  Angiogenic network formation in the developing vertebrate trunk , 2003, Development.

[57]  Anne J. Ridley,et al.  ROCKs: multifunctional kinases in cell behaviour , 2003, Nature Reviews Molecular Cell Biology.

[58]  B. Wiedenmann,et al.  Oxidative Stress Regulates Vascular Endothelial Growth Factor-A Gene Transcription through Sp1- and Sp3-dependent Activation of Two Proximal GC-rich Promoter Elements* , 2003, The Journal of Biological Chemistry.

[59]  V. V. van Hinsbergh,et al.  Involvement of RhoA/Rho Kinase Signaling in VEGF-Induced Endothelial Cell Migration and Angiogenesis In Vitro , 2003, Arteriosclerosis, thrombosis, and vascular biology.

[60]  Christopher S. Chen,et al.  Cells lying on a bed of microneedles: An approach to isolate mechanical force , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[61]  M. Ubukata,et al.  Usage of Tautomycetin, a Novel Inhibitor of Protein Phosphatase 1 (PP1), Reveals That PP1 Is a Positive Regulator of Raf-1 in Vivo * , 2003, The Journal of Biological Chemistry.

[62]  M. Young,et al.  Protein phosphatase‐2A regulates endothelial cell motility and both the phosphorylation and the stability of focal adhesion complexes , 2002, International journal of cancer.

[63]  M. Hori,et al.  Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction. , 2002, Kidney international.

[64]  E. Weinberg,et al.  The role of vascular endothelial growth factor (VEGF) in vasculogenesis, angiogenesis, and hematopoiesis in zebrafish development , 2001, Mechanisms of Development.

[65]  M. Ubukata,et al.  Tautomycetin is a novel and specific inhibitor of serine/threonine protein phosphatase type 1, PP1. , 2001, Biochemical and biophysical research communications.

[66]  K. Karsch,et al.  Loss of cyclin A and G1-cell cycle arrest are a prerequisite of ceramide-induced toxicity in human arterial endothelial cells. , 2001, Cardiovascular research.

[67]  R K Jain,et al.  Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[68]  B. Weinstein,et al.  The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. , 2001, Developmental biology.

[69]  A. Nasevicius,et al.  Yeast Yeast 2000; 17: 294±301. Research Article Distinct requirements for zebra®sh angiogenesis revealed by a VEGF-A morphant , 2000 .

[70]  Fumio Matsumura,et al.  Distinct Roles of Rock (Rho-Kinase) and Mlck in Spatial Regulation of Mlc Phosphorylation for Assembly of Stress Fibers and Focal Adhesions in 3t3 Fibroblasts , 2000, The Journal of cell biology.

[71]  P. Cohen,et al.  The control of protein phosphatase-1 by targetting subunits. The major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1. , 1992, European journal of biochemistry.

[72]  M. Suganuma,et al.  Okadaic Acid Is a Potent Angiogenesis Inducer , 1992, Japanese journal of cancer research : Gann.

[73]  C. Marshall,et al.  ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis. , 2006, Cancer cell.

[74]  B. Weylie,et al.  Role of AKT/PKB signaling in fibroblast growth factor‐1 (FGF‐1)‐induced angiogenesis in the chicken chorioallantoic membrane (CAM) , 2005, Journal of cellular biochemistry.

[75]  J. Mu¨ller,et al.  The University of Bradford Institutional Repository , 2022 .