Practice-induced changes of brain function during visual attention: a parametric fMRI study at 4 Tesla

A parametric functional MRI (fMRI) study with three levels of task difficulty was performed to determine the effect of practice and attentional load on brain activation during visual attention tasks. Brief practice during repeat fMRI scanning (20 min) did not change performance accuracy or reaction times (RT), but decreased activation bilaterally in the inferior, middle, and superior frontal gyri, superior temporal gyrus, thalamus, and cerebellum. Increased attentional load decreased performance accuracy but not RT, and increased activation bilaterally in the inferior, posterior, and superior parietal cortices, thalamus, cerebellum, and frontal gyri. These changes suggest that practice decreases dependency on thalamus, cerebellum, and the frontal cortices for controlled task processing possibly due to increased efficiency of the attentional network. Since short-term practice-effects in the prefrontal cortex may be similar to attentional load-effects, studies of attentional load need to take practice effects into account.

[1]  G. Logan.  Toward an instance theory of automatization. , 1988 .

[2]  J. Desmond,et al.  The neural basis of visual skill learning: an fMRI study of mirror reading. , 1998, Cerebral cortex.

[3]  M Ingvar,et al.  Dynamic changes in the functional anatomy of thehuman brain during recall of abstract designs related topractice , 1999, Neuropsychologia.

[4]  Karl J. Friston,et al.  Nonlinear Regression in Parametric Activation Studies , 1996, NeuroImage.

[5]  Z W Pylyshyn,et al.  Tracking multiple independent targets: evidence for a parallel tracking mechanism. , 1988, Spatial vision.

[6]  Karl J. Friston,et al.  Assessing the significance of focal activations using their spatial extent , 1994, Human brain mapping.

[7]  Edward E. Smith,et al.  Working Memory: A View from Neuroimaging , 1997, Cognitive Psychology.

[8]  J. Gore,et al.  Neural Correlates of the Attentional Blink , 2000, Neuron.

[9]  Alan C. Evans,et al.  Functional Anatomy of Visuomotor Skill Learning in Human Subjects Examined with Positron Emission Tomography , 1996, The European journal of neuroscience.

[10]  Leslie G. Ungerleider,et al.  Mechanisms of directed attention in the human extrastriate cortex as revealed by functional MRI. , 1998, Science.

[11]  M. Raichle,et al.  Emotion-induced changes in human medial prefrontal cortex: I. During cognitive task performance. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[12]  P. Cavanagh,et al.  Attention Response Functions Characterizing Brain Areas Using fMRI Activation during Parametric Variations of Attentional Load , 2001, Neuron.

[13]  A Gevins,et al.  Dynamic cortical networks of verbal and spatial working memory: effects of memory load and task practice. , 1998, Cerebral cortex.

[14]  R. Poldrack,et al.  Characterizing the neural mechanisms of skill learning and repetition priming: evidence from mirror reading. , 2001, Brain : a journal of neurology.

[15]  K. Uğurbil,et al.  High contrast and fast three‐dimensional magnetic resonance imaging at high fields , 1995, Magnetic resonance in medicine.

[16]  Brian Knutson,et al.  Volition to Action—An Event-Related fMRI Study , 2002, NeuroImage.

[17]  S. Petersen,et al.  The effects of practice on the functional anatomy of task performance. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[18]  R. Woods.  Modeling for Intergroup Comparisons of Imaging Data , 1996, NeuroImage.

[19]  Karl J. Friston,et al.  Incorporating Prior Knowledge into Image Registration , 1997, NeuroImage.

[20]  Karl J. Friston,et al.  Statistical parametric maps in functional imaging: A general linear approach , 1994 .

[21]  Karl J. Friston,et al.  Multisubject fMRI Studies and Conjunction Analyses , 1999, NeuroImage.

[22]  P. Cavanagh,et al.  Cortical fMRI activation produced by attentive tracking of moving targets. , 1998, Journal of neurophysiology.

[23]  M. Raichle,et al.  Emotion-induced changes in human medial prefrontal cortex: II. During anticipatory anxiety. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[24]  S. Petersen,et al.  Role of the Cerebellum in Motor Cognition , 2002, Annals of the New York Academy of Sciences.

[25]  J. B. Demb,et al.  Functional Magnetic Resonance Imaging of Semantic Memory Processes in the Frontal Lobes , 1996 .

[26]  C D Frith,et al.  Modulating irrelevant motion perception by varying attentional load in an unrelated task. , 1997, Science.

[27]  C. Koch,et al.  Brain Areas Specific for Attentional Load in a Motion-Tracking Task , 2001, Journal of Cognitive Neuroscience.

[28]  M. Buonocore,et al.  Ghost artifact reduction for echo planar imaging using image phase correction , 1997, Magnetic resonance in medicine.

[29]  Nick F. Ramsey,et al.  Functional Anatomical Correlates of Controlled and Automatic Processing , 2001, Journal of Cognitive Neuroscience.

[30]  Linda Chang,et al.  k-Space based summary motion detection for functional magnetic resonance imaging , 2003, NeuroImage.

[31]  G. Mangun,et al.  Effects of practice on executive control investigated with fMRI. , 2002, Brain research. Cognitive brain research.

[32]  Leslie G. Ungerleider,et al.  The acquisition of skilled motor performance: fast and slow experience-driven changes in primary motor cortex. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[33]  D. Brooks,et al.  Motor sequence learning: a study with positron emission tomography , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[34]  Hugh Garavan,et al.  Practice‐related functional activation changes in a working memory task , 2000, Microscopy research and technique.