A basic sequence in STIM1 promotes Ca2+ influx by interacting with the C-terminal acidic coiled coil of Orai1.
暂无分享,去创建一个
[1] J. Hull,et al. Bombyx mori Homologs of STIM1 and Orai1 Are Essential Components of the Signal Transduction Cascade That Regulates Sex Pheromone Production* , 2009, The Journal of Biological Chemistry.
[2] S. Feske,et al. A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels. , 2009, Biochemical and biophysical research communications.
[3] P. De Camilli,et al. The β- and γ-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells , 2009, Journal of Cell Science.
[4] C. Romanin,et al. Molecular Determinants of the Coupling between STIM1 and Orai Channels , 2009, The Journal of Biological Chemistry.
[5] Elizabeth D. Covington,et al. STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1 , 2009, Cell.
[6] Joseph P. Yuan,et al. SOAR and the polybasic STIM1 domains gate and regulate the Orai channels , 2009, Nature Cell Biology.
[7] Shenyuan L. Zhang,et al. The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers , 2008, Nature.
[8] Tobias Meyer,et al. Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion , 2007, Proceedings of the National Academy of Sciences.
[9] J. Kinet,et al. CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry , 2006, Science.
[10] Bogdan Tanasa,et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function , 2006, Nature.
[11] T. Deerinck,et al. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane , 2005, Nature.
[12] B. Baird,et al. Transmembrane Sequences Are Determinants of Immunoreceptor Signaling 1 , 2005, The Journal of Immunology.
[13] Tobias Meyer,et al. STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx , 2005, Current Biology.
[14] R. Fairman,et al. Design of heterotetrameric coiled coils: evidence for increased stabilization by Glu(-)-Lys(+) ion pair interactions. , 1996, Biochemistry.
[15] J. Kinet,et al. Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions. , 2009, Molecular biology of the cell.
[16] D. Woolfson. The design of coiled-coil structures and assemblies. , 2005, Advances in protein chemistry.