Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease

We assessed whether novelty-related fMRI activity in medial temporal lobe regions and the precuneus follows an inverted U-shaped pattern across the clinical spectrum of increased Alzheimer

[1]  M. Reuter,et al.  Amyloid pathology but not APOE ε4 status is permissive for tau-related hippocampal dysfunction , 2022, Brain : a journal of neurology.

[2]  Theresa M. Harrison,et al.  Reduced Repetition Suppression in Aging is Driven by Tau–Related Hyperactivity in Medial Temporal Lobe , 2021, The Journal of Neuroscience.

[3]  M. Ewers,et al.  FDG-PET hypermetabolism is associated with higher tau-PET in mild cognitive impairment at low amyloid-PET levels , 2020, Alzheimer's research & therapy.

[4]  R. Buchert,et al.  Abnormal Regional and Global Connectivity Measures in Subjective Cognitive Decline Depending on Cerebral Amyloid Status. , 2020, Journal of Alzheimer's disease : JAD.

[5]  S. Duchesne,et al.  A quadratic function of activation in individuals at risk of Alzheimer's disease , 2020, Alzheimer's & dementia.

[6]  Danilo Bzdok,et al.  An improved neuroanatomical model of the default-mode network reconciles previous neuroimaging and neuropathological findings , 2019, Communications Biology.

[7]  David Berron,et al.  Alzheimer's pathology targets distinct memory networks in the ageing brain. , 2019, Brain : a journal of neurology.

[8]  W. Jagust,et al.  Relationships Between Tau and Glucose Metabolism Reflect Alzheimer's Disease Pathology in Cognitively Normal Older Adults. , 2019, Cerebral cortex.

[9]  M. Sortino,et al.  Early compensatory responses against neuronal injury: A new therapeutic window of opportunity for Alzheimer's Disease? , 2018, CNS neuroscience & therapeutics.

[10]  Reisa A. Sperling,et al.  Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity , 2018, The Journal of Neuroscience.

[11]  F. Jessen,et al.  CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume , 2018, Alzheimer's & dementia.

[12]  S. Sorbi,et al.  From Subjective Cognitive Decline to Alzheimer's Disease: The Predictive Role of Neuropsychological Assessment, Personality Traits, and Cognitive Reserve. A 7-Year Follow-Up Study. , 2018, Journal of Alzheimer's disease : JAD.

[13]  F. Jessen,et al.  Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE) , 2018, Alzheimer's Research & Therapy.

[14]  Chris M. Foster,et al.  Both hyper- and hypo-activation to cognitive challenge are associated with increased beta-amyloid deposition in healthy aging: A nonlinear effect , 2018, NeuroImage.

[15]  Henrik Zetterberg,et al.  Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity , 2017, Nature Communications.

[16]  David T. Jones,et al.  Defining imaging biomarker cut points for brain aging and Alzheimer's disease , 2017, Alzheimer's & Dementia.

[17]  Jorge Sepulcre,et al.  Fluorodeoxyglucose metabolism associated with tau‐amyloid interaction predicts memory decline , 2017, Annals of neurology.

[18]  S. A. Hussaini,et al.  Neuronal activity enhances tau propagation and tau pathology in vivo , 2016, Nature Neuroscience.

[19]  Marnie E. Shaw,et al.  Cerebral atrophy in mild cognitive impairment: A systematic review with meta-analysis , 2015, Alzheimer's & dementia.

[20]  David T. Jones,et al.  Cascading network failure across the Alzheimer’s disease spectrum , 2015, Brain : a journal of neurology.

[21]  K. Langa,et al.  The diagnosis and management of mild cognitive impairment: a clinical review. , 2014, JAMA.

[22]  A. Mitchell,et al.  Risk of dementia and mild cognitive impairment in older people with subjective memory complaints: meta‐analysis , 2014, Acta psychiatrica Scandinavica.

[23]  Andrew J. Saykin,et al.  A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease , 2014, Alzheimer's & Dementia.

[24]  M. Rajah,et al.  Age-related differences in brain activity in the subsequent memory paradigm: A meta-analysis , 2014, Neuroscience & Biobehavioral Reviews.

[25]  Cindee M. Madison,et al.  Neural compensation in older people with brain β-amyloid deposition , 2014, Nature Neuroscience.

[26]  Keith A. Johnson,et al.  Amyloid Deposition Is Linked to Aberrant Entorhinal Activity among Cognitively Normal Older Adults , 2014, The Journal of Neuroscience.

[27]  Amanda V. Utevsky,et al.  Precuneus Is a Functional Core of the Default-Mode Network , 2014, The Journal of Neuroscience.

[28]  Elizabeth C Mormino,et al.  Aβ Deposition in aging is associated with increases in brain activation during successful memory encoding. , 2012, Cerebral cortex.

[29]  F. Jessen,et al.  Glucose metabolism, gray matter structure and memory decline in subjective memory impairment , 2012, Alzheimer's & Dementia.

[30]  Deepti Putcha,et al.  Age and amyloid-related alterations in default network habituation to stimulus repetition , 2012, Neurobiology of Aging.

[31]  Amy L. Shelton,et al.  Reduction of Hippocampal Hyperactivity Improves Cognition in Amnestic Mild Cognitive Impairment , 2012, Neuron.

[32]  Kelly O'Keefe,et al.  Hippocampal Hyperactivation Associated with Cortical Thinning in Alzheimer's Disease Signature Regions in Non-Demented Elderly Adults , 2011, The Journal of Neuroscience.

[33]  Z. Walker,et al.  Subjective cognitive impairment: Functional MRI during a divided attention task , 2011, European Psychiatry.

[34]  H. Walter,et al.  Evidence of neuronal compensation during episodic memory in subjective memory impairment. , 2011, Archives of general psychiatry.

[35]  J. Morris,et al.  The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[36]  Karl J. Friston,et al.  Diffeomorphic registration using geodesic shooting and Gauss–Newton optimisation , 2011, NeuroImage.

[37]  Hans-Jochen Heinze,et al.  Functional phenotyping of successful aging in long‐term memory: Preserved performance in the absence of neural compensation , 2010, Hippocampus.

[38]  L. Mucke,et al.  Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks , 2010, Nature Neuroscience.

[39]  Maija Pihlajamäki,et al.  Functional MRI Assessment of Task-Induced Deactivation of the Default Mode Network in Alzheimer’s Disease and At-Risk Older Individuals , 2009, Behavioural neurology.

[40]  Keith A. Johnson,et al.  Amyloid Deposition Is Associated with Impaired Default Network Function in Older Persons without Dementia , 2009, Neuron.

[41]  Maija Pihlajamäki,et al.  Impaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease. , 2008, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[42]  R. Sperling,et al.  Hippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline , 2007, Journal of Neurology, Neurosurgery, and Psychiatry.

[43]  Michael Erb,et al.  Hippocampal activation in patients with mild cognitive impairment is necessary for successful memory encoding , 2007, Journal of Neurology, Neurosurgery & Psychiatry.

[44]  Vince D. Calhoun,et al.  Alterations in Memory Networks in Mild Cognitive Impairment and Alzheimer's Disease: An Independent Component Analysis , 2006, The Journal of Neuroscience.

[45]  C. Jack,et al.  Comparison of memory fMRI response among normal, MCI, and Alzheimer’s patients , 2003, Neurology.

[46]  A. Dale,et al.  Whole Brain Segmentation Automated Labeling of Neuroanatomical Structures in the Human Brain , 2002, Neuron.

[47]  S. Belleville,et al.  Effect of disease severity on neural compensation of item and associative recognition in mild cognitive impairment. , 2012, Journal of Alzheimer's disease : JAD.

[48]  H. Braak,et al.  Neuropathological stageing of Alzheimer-related changes , 2004, Acta Neuropathologica.