Central Nervous System

A construction worker falls from a scaffold that was positioned at the second-story level of a building. He has a severe closed heal injury with a Glasgow Coma Scale of 6. Admission computed tomography (CT) scan demonstrates diffuse axonal injury. No other injuries were found on secondary evaluation and CT evaluation of the cervical spine, chest, and abdomen. Which of the following is the preferred management for this patient? (A) Forced diuresis (B) Barbiturate administration (C) Hyperventilation (72 hours) (D) Craniotomy (E) Intracranial pressure monitoring

[1]  T. Ryken,et al.  Radiographic Assessment of the Cervical Spine in Asymptomatic Trauma Patients. , 2002, Neurosurgery.

[2]  J. Hinds,et al.  Aging in the rat olfactory bulb: Quantitative changes in mitral cell organelles and somato‐dendritic synapses , 1979, The Journal of comparative neurology.

[3]  W. Andrew.  Cytological changes in senility in the trigeminal ganglion, spinal cord and brain of the mouse. , 1941, Journal of anatomy.

[4]  D. Moseley,et al.  Cartilage cells in cerebrospinal fluid. , 1990, Archives of pathology & laboratory medicine.

[5]  H. Brody,et al.  Structural Changes in the Aging Nervous System , 1970 .

[6]  J. Antonen,et al.  Acute multiple sclerosis exacerbations are characterized by low cerebrospinal fluid suppressor/cytotoxic T‐cells , 1987, Acta neurologica Scandinavica.

[7]  M. Mcginnis.  Detection of fungi in cerebrospinal fluid. , 1983, The American journal of medicine.

[8]  P. Gupta,et al.  Diagnosis of central nervous system Toxoplasma gondii from the cerebrospinal fluid in a patient with acquired immunodeficiency syndrome , 1987, Diagnostic cytopathology.

[9]  D. Commins,et al.  Cytologic Features of Hemangioblastoma , 1998, Acta Cytologica.

[10]  K. Brizzee,et al.  Lipofuscin: Intra- and Extraneuronal Accumulation and Regional Distribution , 1975 .

[11]  E. Fifková.  The effect of unilateral deprivation on visual centers in rats , 1970, The Journal of comparative neurology.

[12]  S. Blasius,et al.  Melanotic progonoma of the brain: a case report and review , 1998, Child's Nervous System.

[13]  S. T. G. Roup,et al.  Correction: Validity of a Set of Clinical Criteria to Rule out Injury to the Cervical Spine in Patients with Blunt Trauma. , 2000, The New England journal of medicine.

[14]  Alan Peters,et al.  Smooth and sparsely‐spined stellate cells in the visual cortex of the rat: A study using a combined golgi‐electron microscope technique , 1978, The Journal of comparative neurology.

[15]  M. Jordá,et al.  Cytologic characteristics of meningeal carcinomatosis: increased diagnostic accuracy using carcinoembryonic antigen and epithelial membrane antigen immunocytochemistry. , 1998, Archives of neurology.

[16]  H. Wiśniewski,et al.  Chemical relationship of the paired helical filaments of Alzheimer's dementia to normal human neurofilaments and neurotubules , 1978, Brain Research.

[17]  William Bondari,et al.  Age Changes in the Neuronal Microenvironment , 1972, Science.

[18]  E. Fifková.  The effect of monocular deprivation on the synaptic contacts of the visual cortex. , 1969, Journal of neurobiology.

[19]  D. W. Vaughan.  MEMBRANOUS BODIES IN THE CEREBRAL CORTEX OF AGING RATS: AN ELECTRON MICROSCOPE STUDY , 1976, Journal of neuropathology and experimental neurology.

[20]  M. Feldman,et al.  Loss of dendritic spines in aging cerebral cortex , 1975, Anatomy and Embryology.

[21]  E. Moore,et al.  Blunt carotid arterial injuries: implications of a new grading scale. , 1999, The Journal of trauma.

[22]  Y. Suh,et al.  Dysembryoplastic Neuroepithelial Tumor , 2003, Acta Cytologica.

[23]  T. Ryken,et al.  Management of Vertebral Artery Injuries after Nonpenetrating Cervical Trauma. , 2002, Neurosurgery.

[24]  R. Pai,et al.  Choroid plexus papilloma diagnosed by crush cytology , 2001, Diagnostic cytopathology.

[25]  R. McLendon,et al.  Papillary glioneuronal tumor: a new variant of mixed neuronal-glial neoplasm. , 1998, The American journal of surgical pathology.

[26]  E. Gasparetto,et al.  Pleomorphic xanthoastrocytoma: Report of a case diagnosed by intraoperative cytopathological examination , 2001, Diagnostic cytopathology.

[27]  T. Ryken,et al.  Treatment of Subaxial Cervical Spinal Injuries. , 2013, Neurosurgery.

[28]  K. Brizzee.  Aging Changes in Relation to Diseases of the Nervous System , 1975 .

[29]  A. Scheibel,et al.  Neuronal changes in the aging mouse: Spinal cord and lower brain stem , 1977, Experimental Neurology.

[30]  Steroids and gunshot wounds to the spine. , 1997, Neurosurgery.

[31]  A. Parwani,et al.  Atypical teratoid/rhabdoid tumor of the brain , 2005, Cancer.

[32]  Johnston Ww,et al.  The cytopathology of cerebrospinal fluid. II. Metastatic cancer, meningeal carcinomatosis and primary central nervous system neoplasms. , 1981 .

[33]  Alan Peters,et al.  THE SMALL PYRAMIDAL NEURON OF THE RAT CEREBRAL CORTEX , 1968, Zeitschrift für Zellforschung und Mikroskopische Anatomie.

[34]  G. Velmahos,et al.  Radiographic cervical spine evaluation in the alert asymptomatic blunt trauma victim: much ado about nothing. , 1996, The Journal of trauma.

[35]  B. Cragg,et al.  The density of synapses and neurons in normal, mentally defective ageing human brains. , 1975, Brain : a journal of neurology.

[36]  B. Cole,et al.  Cerebrospinal fluid cytology in patients with cancer , 1998, Cancer.

[37]  M. Oehmichen,et al.  Eosinophilic granulocytes in cerebrospinal fluid: Analysis of 94 cerebrospinal fluid specimens and review of the literature , 1978, Journal of Neurology.

[38]  F. Valverde,et al.  Apical dendritic spines of the visual cortex and light deprivation in the mouse , 2004, Experimental Brain Research.

[39]  A. Parwani,et al.  Gliosarcoma: Cytopathologic characteristics on fine‐needle aspiration (FNA) and intraoperative touch imprint , 2004, Diagnostic cytopathology.

[40]  E. Thiel,et al.  CSF evaluation in primary CNS lymphoma patients by PCR of the CDR III IgH genes , 2002, Neurology.

[41]  E. Hook,et al.  A Trichomonas species in a mixed microbial meningitis. , 1976, JAMA.

[42]  J. Johnson,et al.  Changes in Microanatomy, Neurocytology and Fine Structure with Aging , 1975 .

[43]  D. Maxwell,et al.  Ultrastructural changes in neurons of the spinal anterior horn of ageing mice with particular reference to the accumulation of lipofuscin pigment , 1974, Journal of neurocytology.

[44]  M. Chamberlain,et al.  A comparison between ventricular and lumbar cerebrospinal fluid cytology in adult patients with leptomeningeal metastases. , 2001, Neuro-oncology.

[45]  M. Berlière,et al.  Two schwannomas presenting as lumps in the same breast , 1997, Diagnostic cytopathology.

[46]  R. Narayan,et al.  Intracranial pressure: to monitor or not to monitor? A review of our experience with severe head injury. , 1982, Journal of neurosurgery.

[47]  J. Johnson,et al.  CHAPTER 4 – Lipofuscin: Fine-Structural and Biochemical Studies , 1977 .

[48]  M. Yamada,et al.  Quantitative study on dendrites and dendritic spines in Alzheimer's disease and senile dementia. , 1975, Advances in neurology.

[49]  T. Ryken,et al.  Pharmacological therapy after acute cervical spinal cord injury. , 2002, Neurosurgery.

[50]  H. Stellbrink,et al.  Limited value of cerebrospinal fluid for direct detection ofToxoplasma gondii in toxoplasmic encephalitis associated with AIDS , 1995, Journal of Neurology.

[51]  R. W. Young,et al.  Rhythmic daily shedding of outer-segment membranes by visual cells in the goldfish , 1978, The Journal of cell biology.

[52]  R. S. Williams,et al.  THE GOLGI RAPID METHOD IN CLINICAL NEUROPATHOLOGY: THE MORPHOLOGIC CONSEQUENCES OF SUBOPTIMAL FIXATION , 1978, Journal of neuropathology and experimental neurology.

[53]  H. Wiśniewski,et al.  Infectious etiology of neuritic (senile) plaques in mice , 1975, Science.

[54]  A. Lieberman,et al.  Neurons and their synaptic organization in the visual cortex of the rat , 1977, Cell and Tissue Research.

[55]  D. W. Vaughan.  Age‐related deterioration of pyramidal cell basal dendrites in rat auditory cortex , 1977, The Journal of comparative neurology.

[56]  A. Jouvet,et al.  Papillary Tumor of the Pineal Region , 2003, The American journal of surgical pathology.

[57]  C. Sundaram,et al.  Intraoperative cytology (squash smear) in neurosurgical practice – pitfalls in diagnosis experience based on 3057 samples from a single institution , 2007, Cytopathology : official journal of the British Society for Clinical Cytology.

[58]  R. Sturrock.  Changes in neurologia and myelination in the white matter of aging mice. , 1976, Journal of gerontology.

[59]  M. Apuzzo,et al.  The Significance of Subarachnoid Hemorrhage after Penetrating Craniocerebral Injury , 1993 .

[60]  B. Pasquier,et al.  Primary malignant melanoma of the cerebellum. A case with metastases outside the nervous system , 1978, Cancer.

[61]  K. Jellinger,et al.  Primary central nervous system lymphomas—an update , 2005, Journal of Cancer Research and Clinical Oncology.

[62]  T. Powell,et al.  Morphological variations in the dendritic spines of the neocortex. , 1969, Journal of cell science.

[63]  J. Ordy,et al.  Age pigments, cell loss and hippocampal function , 1979, Mechanisms of Ageing and Development.

[64]  G. Aimard,et al.  Plasma cells in cerebrospinal fluid and multiple sclerosis: diagnostic yield and clinicobiological correlations , 1986, Acta neurologica Scandinavica.

[65]  M. Apuzzo,et al.  Patients with Glasgow Coma Scale scores 3, 4, 5 after gunshot wounds to the brain. , 1995, Neurosurgery clinics of North America.

[66]  W. Hunt,et al.  Surgical risk as related to time of intervention in the repair of intracranial aneurysms. , 1968, Journal of neurosurgery.

[67]  J. Tilgner,et al.  Validation of Intraoperative Diagnoses Using Smear Preparations from Stereotactic Brain Biopsies: Intraoperative versus Final Diagnosis—Influence of Clinical Factors , 2005, Neurosurgery.

[68]  M. Feldman.  Dendritic Changes in Aging Rat Brain: Pyramidal Cell Dendrite Length and Ultrastructure , 1977 .

[69]  Warren Andrew,et al.  Neuronophagia in the brain of the mouse as a result of inanition, and in the normal aging process , 1939 .

[70]  L. Rothblat,et al.  The effect of monocular deprivation on dendritic spines in visual cortex of young and adult albino rats: evidence for a sensitive period , 1979, Brain Research.

[71]  Sholl Da.  Dendritic organization in the neurons of the visual and motor cortices of the cat. , 1953 .

[72]  K. Kuypers,et al.  Effects of differential environments on plasticity of dendrites of cortical pyramidal neurons in adult rats , 1978, Experimental Neurology.

[73]  A. Peters,et al.  The forms of non‐pyramidal neurons in the visual cortex of the rat , 1978, The Journal of comparative neurology.

[74]  A. Peters,et al.  Neuroglial cells in the cerebral cortex of rats from young adulthood to old age: An electron microscope study , 1974, Journal of neurocytology.

[75]  H. Eisenberg,et al.  High-dose barbiturate control of elevated intracranial pressure in patients with severe head injury. , 1988, Journal of neurosurgery.

[76]  W. Bondareff,et al.  Age changes in the neuronal microenvironment. , 1972, Science.

[77]  H. Wiśniewski,et al.  EFFECTS OF MITOTIC SPINDLE INHIBITORS ON NEUROTUBULES AND NEUROFILAMENTS IN ANTERIOR HORN CELLS , 1968, The Journal of cell biology.

[78]  H. Ng.  Smears in the Diagnosis of Pituitary Adenomas , 1998, Acta Cytologica.

[79]  E. White.  Identified neurons in mouse smi cortex which are postsynaptic to thalamocortical axon terminals: A combined golgi‐electron microscopic and degeneration study , 1978, The Journal of comparative neurology.

[80]  D. W. Vaughan,et al.  Ultrastructure of neurons in the auditory cortex of ageing rats: a morphometric study , 1979, Journal of neurocytology.

[81]  Spine and spinal cord , 2004 .

[82]  G. Velmahos,et al.  Variability in computed tomography and magnetic resonance imaging in patients with cervical spine injuries. , 2002, The Journal of trauma.

[83]  M. Morimatsu,et al.  Cytodiagnosis of Central Neurocytoma in Intraoperative Preparations , 2004, Acta Cytologica.

[84]  T. Ryken,et al.  Blood pressure management after acute spinal cord injury. , 2002, Neurosurgery.

[85]  S. Jaffe,et al.  Cerebrospinal fluid analysis in multiple sclerosis. , 2007, International review of neurobiology.

[86]  K. Ho,et al.  Primary leptomeningeal gliomatosis: symptoms suggestive of meningitis. , 1981, Archives of neurology.

[87]  J R Hoffman,et al.  Selective cervical spine radiography in blunt trauma: methodology of the National Emergency X-Radiography Utilization Study (NEXUS). , 1998, Annals of emergency medicine.

[88]  A. Scheibel,et al.  Synaptic loci on visual cortical neurons of the rabbit: the specific afferent radiation. , 1967, Experimental neurology.

[89]  E. Uemura,et al.  RNA content and volume of nerve cell bodies in human brain. I. Prefrontal cortex in aging normal and demented patients. , 1978, Journal of Neuropathology and Experimental Neurology.

[90]  B. Strehler,et al.  Lipofuscin pigment accumulation as a function of age and distribution in rodent brain. , 1968, Journal of gerontology.

[91]  H. Shiraki,et al.  STUDY OF AXONAL DYSTROPHY. I. PATHOLOGY OF THE NEUROPIL OF THE GRACILE AND THE CUNEATE NUCLEI IN AGEING AND OLD RATS: A STEREOLOGICAL STUDY , 1978, Neuropathology and applied neurobiology.

[92]  J. Killian,et al.  A modified membrane-filter technic for detection of cancer cells in body fluids. , 1961, Technical bulletin of the Registry of Medical Technologists. American Society of Clinical Pathologists. Registry of Medical Technologists.

[93]  A. Roma,et al.  Lymphoid and myeloid neoplasms involving cerebrospinal fluid: Comparison of morphologic examination and immunophenotyping by flow cytometry , 2002, Diagnostic cytopathology.

[94]  A. Parwani,et al.  Colloid cyst of the third ventricle: Cytomorphologic features on stereotactic fine‐needle aspiration , 2002, Diagnostic cytopathology.

[95]  H. Wiśniewski,et al.  Ultrastructure of Senile Dementia and of Experimental Analogs , 1972 .

[96]  N. Mei,et al.  Modification quantitative des baˆtonnets intranucléaires des neurones sympathiques sous l'influence de la stimulationélectrique , 1971 .

[97]  V. Manucha,et al.  Atypical Lymphoid Cells in Cerebrospinal Fluid in Acute Epstein Barr Virus Infection , 2008, Acta Cytologica.

[98]  P. Huttenlocher.  Synaptic density in human frontal cortex - developmental changes and effects of aging. , 1979, Brain research.

[99]  J. Silverman,et al.  Intraoperative cytologic diagnosis of suprasellar and sellar cystic lesions , 1999, Diagnostic cytopathology.

[100]  A. Peters,et al.  A new procedure for examining Golgi impregnated neurons by light and electron microscopy , 1977, Journal of neurocytology.

[101]  H. Ng,et al.  Cytodiagnosis of Pilocytic Astrocytoma in Smear Preparations , 1998, Acta Cytologica.

[102]  S. Rees.  A quantitative electron microscopic study of atypical structures in normal human cerebral cortex , 1975, Anatomy and Embryology.

[103]  I. Beus,et al.  Characteristics of cerebrospinal fluid in tuberculous meningitis. , 1982, Acta cytologica.

[104]  S. Hirschman,et al.  Mycobacterial meningitis. Retrospective analysis from 1970 to 1983. , 1985, The American journal of medicine.

[105]  W. Saeger,et al.  Pineal region tumours of childhood , 1987, European Journal of Pediatrics.

[106]  A. Scheibel,et al.  The aging human betz cell , 1977, Experimental Neurology.

[107]  P. Pilz.  [Cerebrospinal fluid and multiple sclerosis]. , 1985, Wiener medizinische Wochenschrift.

[108]  J. Bruner,et al.  Cerebrospinal fluid manifestations of the neurologic complications of human immunodeficiency virus infection. , 1989, Acta cytologica.

[109]  E. Moore,et al.  The devastating potential of blunt vertebral arterial injuries. , 2000, Annals of surgery.

[110]  R. Nishikawa,et al.  Cytologic Features of Chordoid Meningioma , 2004, Acta Cytologica.

[111]  P. Gupta,et al.  Herpes simplex encephalitis, cerebrospinal fluid cytology studies. Two case reports. , 1972, Acta cytologica.

[112]  M. Bhattacharjee,et al.  Chordoid Glioma of the Third Ventricle , 2006, Acta Cytologica.

[113]  Meilin Liu,et al.  Thrombolysis (different doses, routes of administration and agents) for acute ischaemic stroke. , 2013, The Cochrane database of systematic reviews.

[114]  J. Bernaudin,et al.  Cytologic features of cerebrospinal fluid in Lyme disease. , 1987, Acta cytologica.

[115]  J. Boyett,et al.  Comparison of cisternal and lumbar CSF examination in leptomeningeal metastasis , 1992, Neurology.

[116]  G. Sorenson,et al.  A comparison of polymerase chain reaction examination of cerebrospinal fluid and conventional cytology in the diagnosis of lymphomatous meningitis , 1996, Cancer.

[117]  E. Moore,et al.  The unrecognized epidemic of blunt carotid arterial injuries: early diagnosis improves neurologic outcome. , 1998, Annals of surgery.

[118]  Bigner Sh,et al.  The cytopathology of cerebrospinal fluid. I. Nonneoplastic conditions, lymphoma and leukemia. , 1981 .

[119]  H. Wiśniewski,et al.  Neurofibrillary tangles of paired helical filaments , 1976, Journal of the Neurological Sciences.

[120]  R. Adkins,et al.  Use of methylprednisolone as an adjunct in the management of patients with penetrating spinal cord injury: outcome analysis. , 1996, Neurosurgery.

[121]  Johnston Ww,et al.  The diagnostic challenge of tumors manifested initially by the shedding of cells into cerebrospinal fluid. , 1984 .

[122]  M. Kaps,et al.  Meningeal carcinomatosis: CSF cytology, immunocytochemistry and biochemical tumor markers , 1994, Acta neurologica Scandinavica.

[123]  I. Boukovinas,et al.  Diagnosis of Metastatic Tumors in Cerebrospinal Fluid Samples Using Thin-Layer Cytology , 2008, Acta Cytologica.

[124]  W. Wilson,et al.  Detection of malignant hematopoietic cells in cerebral spinal fluid previously diagnosed as atypical or suspicious , 2006, Cancer.

[125]  J W Hinds,et al.  Aging of the rat olfactory bulb: Growth and atrophy of constituent layers and changes in size and number of mitral cells , 1977, The Journal of comparative neurology.

[126]  H. Kalter,et al.  Teratology of the central nervous system , 1970 .

[127]  K. Roessler,et al.  High Diagnostic Accuracy of Cytologic Smears of Central Nervous System Tumors , 2002, Acta Cytologica.

[128]  Y. Geinisman,et al.  Partial deafferentation of neurons in the dentate gyrus of the senescent rat , 1977, Brain Research.

[129]  J. Johnson,et al.  Fine structural changes in the lateral vestibular nucleus of aging rats. , 1974, Mechanisms of ageing and development.

[130]  W. Mehler,et al.  A fine structural study of degenerative changes in the dorsal column nuclei of aging mice. Lack of protection by vitamin E. , 1975, Journal of gerontology.

[131]  K. Verma,et al.  Langerhans cell histiocytosis infiltration in cerebrospinal fluid: A case report , 2001, Diagnostic cytopathology.

[132]  D. Munro,et al.  EXTRADURAL HEMORRHAGE A STUDY OF FOBTY‐FOUB CASKS , 1941 .

[133]  L. Skoog,et al.  Diagnosis of lymphoma, leukemia, and metastatic tumor involvement of the cerebrospinal fluid by cytology and immunocytochemistry , 1995, Diagnostic cytopathology.

[134]  U. de Girolami,et al.  Cytologic Features of Pilocytic Astrocytoma in Cerebrospinal Fluid Specimens , 2004, Acta Cytologica.

[135]  H. Wiśniewski,et al.  NEURITIC (SENILE) PLAQUES AND FILAMENTOUS CHANGES IN AGED RHESUS MONKEYS , 1973, Journal of neuropathology and experimental neurology.

[136]  D. Bigner,et al.  The use of a panel of monoclonal antibodies in the evaluation of cytologic specimens from the central nervous system. , 1987, Acta cytologica.

[137]  P. Adam,et al.  Cerebrospinal Fluid Cytologic Findings in Multiple Sclerosis , 2001, Acta Cytologica.

[138]  C. Li,et al.  Cytologic and immunocytochemical studies of cerebrospinal fluid in meningeal sarcoidosis. A case report. , 1992, Acta cytologica.

[139]  J. Mandell,et al.  Granular cell tumor of the neurohypophysis: Report of a case with intraoperative cytologic diagnosis , 2008, Diagnostic cytopathology.

[140]  P. Pfitzer,et al.  Cerebrospinal fluid and metastasis of transitional cell carcinoma of the bladder. , 1982, Acta cytologica.

[141]  G. Arendt,et al.  Primary malignant melanoblastosis of the meninges. Clinical, cytologic and neuropathologic findings in a case. , 1988, Acta cytologica.

[142]  E. Murphy,et al.  VOLUME OF THE VENTRAL COCHLEAR NUCLEUS IN MAN: ITS RELATIONSHIP TO NEURONAL POPULATION AND AGE , 1972, Journal of neuropathology and experimental neurology.

[143]  M. Melamed,et al.  identification of Cryptococcus neoformans in cytologic preparations of cerebrospinal fluid. , 1977, American journal of clinical pathology.

[144]  J. Ordy,et al.  Age differences in short-term memory and cell loss in the cortex of the rat. , 1978, Gerontology.

[145]  B. Scheithauer,et al.  Comprar Tumors of the Central Nervous System . Vol. 7 - AFIP Atlas of Tumor Pathology Series IV | Bernd W. Scheithauer | 9781933477015 | American Registry of Pathology , 2007 .

[146]  A. Peters,et al.  The Structure of Neuritic Plaques in the Cerebral Cortex of Aged Rats , 1981, Journal of neuropathology and experimental neurology.

[147]  A. Peters,et al.  The projection of the lateral geniculate nucleus to area 17 of the rat cerebral cortex. V. Degenerating axon terminals synapsing with Golgi impregnated neurons , 1979, Journal of neurocytology.

[148]  G. Norkrans,et al.  Cytological and immunoglobulin findings in cerebrospinal fluid of symptomatic and asymptomatic human immunodeficiency virus (HIV) seropositive patients , 2005, Infection.

[149]  C. Shaffrey,et al.  Classification of civilian craniocerebral gunshot wounds: a multivariate analysis predictive of mortality. , 1992, Journal of neurotrauma.

[150]  H BRODY,et al.  Organization of the cerebral cortex. III. A study of aging in the human cerebral cortex , 1955, The Journal of comparative neurology.

[151]  J. Jane,et al.  Multivariate analysis and prediction of outcome following penetrating head injury. , 1995, Neurosurgery clinics of North America.

[152]  P. Brodal.  The Central Nervous System , 1992 .

[153]  M. Apuzzo,et al.  The significance of subarachnoid hemorrhage after penetrating craniocerebral injury: correlations with angiography and outcome in a civilian population. , 1993, Neurosurgery.

[154]  J. Collazos.  Opportunistic Infections of the CNS in Patients with AIDS , 2003, CNS drugs.

[155]  J. R. Roberts,et al.  Reappraisal of the "coma cocktail". Dextrose, flumazenil, naloxone, and thiamine. , 1994, Emergency medicine clinics of North America.

[156]  K. Brizzee.  Quantitative histological studies on aging changes in cerebral cortex of Rhesus monkey and albino rat with notes on effects of prolonged low-dose ionizing irradiation in the rat. , 1973, Progress in brain research.

[157]  W. Bondareff,et al.  Changes in the Neuronal Microenvironment Associated with Aging , 1975 .

[158]  A. Ferraro.  VASCULAR CHANGES IN EXPERIMENTAL ANAPHYLAXIS OF THE BRAIN , 1945 .

[159]  E. Moore,et al.  Treatment-Related Outcomes From Blunt Cerebrovascular Injuries: Importance of Routine Follow-Up Arteriography , 2002, Annals of surgery.

[160]  Alan Peters,et al.  The bilaminar and banded distribution of the callosal terminals in the posterior neocortex of the rat , 1979, Brain Research.

[161]  W. Feiden,et al.  Primäre ZNS-Lymphome , 2002, Der Pathologe.

[162]  A. Peters,et al.  The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines. , 1970, The American journal of anatomy.

[163]  N. Kitchen,et al.  Primary malignant melanoma of the cerebellopontine angle. , 2001, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

[164]  H. Prosch,et al.  Demonstration of CD1a positive cells in the cerebrospinal fluid--A clue to diagnosis of isolated Langerhans cell histiocytosis of the hypothalamic-pituitary axis? , 2003, Medical and pediatric oncology.

[165]  R. Oye,et al.  Are polymorphonuclear leukocytes an abnormal finding in cerebrospinal fluid? Results from 225 normal cerebrospinal fluid specimens. , 1988, Archives of internal medicine.

[166]  Y. Geinisman,et al.  Decrease in the number of synapses in the senescent brain: A quantitative electron microscopic analysis of the dentate gyrus molecular layer in the rat , 1976, Mechanisms of Ageing and Development.

[167]  A. Peters,et al.  Intranuclear rods and sheets in rat cochlear nucleus , 1972, Journal of neurocytology.

[168]  T. Hirose,et al.  Qualitative and Quantitative Analysis of Cytologic Assessment of Astrocytoma, Oligodendroglioma and Oligoastrocytoma , 2007, Acta Cytologica.

[169]  Perikala V. Kumar,et al.  Cytologic Findings of Medulloblastoma in Crush Smears , 2001, Acta Cytologica.

[170]  A. Globus,et al.  The effect of continuous illumination on the development of cortical neurons in the rat: A Golgi study , 1976, Experimental Neurology.

[171]  Y. Geinisman.  Loss of axosomatic synapses in the dentate gyrus of aged rats , 1979, Brain Research.

[172]  S. Bigner.  Cerebrospinal Fluid (CSF) Cytology: Current Status and Diagnostic Applications , 1992, Journal of neuropathology and experimental neurology.

[173]  M. Melamed,et al.  Detection of DNA abnormalities by flow cytometry in cells from cerebrospinal fluid. , 1987, American journal of clinical pathology.

[174]  J. Meixensberger,et al.  The Value of Intraoperative Smear Examination of Stereotaxic Brain Specimens , 2006, Minimally invasive neurosurgery : MIN.

[175]  A. Peters,et al.  The choroid plexus of the mature and aging rat: The choroidal epithelium , 1979, The Anatomical record.

[176]  U. de Girolami,et al.  Cerebrospinal fluid cytology in patients with ependymoma , 2008, Cancer.

[177]  G. Schaltenbrand.  Plexus und Meningen , 1955 .

[178]  P. Glees,et al.  Ultrastructural age changes in hippocampal neurons, synapses and neuroglia. , 1973, Experimental gerontology.

[179]  W. Krieg.  Connections of the cerebral cortex. I. The albino rat. A. Topography of the cortical areas , 1946 .

[180]  C. L. Dolman.  Melanotic medulloblastoma , 2004, Acta Neuropathologica.

[181]  F. Bosman,et al.  Value of cerebrospinal fluid cytology for the diagnosis of malignancies in the central nervous system. , 1978, Journal of neurosurgery.

[182]  L. McAllister.  Primary central nervous system lymphoma: A review , 2002, Current neurology and neuroscience reports.

[183]  E. Gasparetto,et al.  Dysembrioplastic neuroepithelial tumor: Cytological diagnosis by intraoperative smear preparation , 2002, Diagnostic cytopathology.

[184]  G. Bots,et al.  Blood-stained cerebrospinal fluid: traumatic puncture or haemorrhage? , 1981, Journal of neurology, neurosurgery, and psychiatry.

[185]  R. Prayson,et al.  Cerebrospinal fluid cytology: an 11-year experience with 5951 specimens. , 1998, Archives of pathology & laboratory medicine.

[186]  J. Meyer,et al.  Occlusive cerebrovascular disease. Pathogenesis and treatment. , 1961 .

[187]  B. Scheithauer,et al.  Histologically confirmed pineal tumors and other germ cell tumors of the brain , 1996, Cancer.

[188]  E. J. Field,et al.  Intranuclear inclusions in neurones and glia: a study in the ageing mouse. , 1971, Gerontologia.

[189]  B. Jennett,et al.  Assessment of coma and impaired consciousness. A practical scale. , 1974, Lancet.

[190]  R. Teoh,et al.  Polymorphonuclear pleocytosis in the cerebrospinal fluid during chemotherapy for tuberculous meningitis , 1986, Journal of Neurology.

[191]  R. Gupta,et al.  Cytodiagnosis of neoplasms of the central nervous system in cerebrospinal fluid samples with an application of selective immunostains in differentiation , 2004, Cytopathology : official journal of the British Society for Clinical Cytology.

[192]  N. Jhala,et al.  Cytology of primary central nervous system neoplasms in cerebrospinal fluid specimens , 2002, Diagnostic cytopathology.

[193]  S. Bigner,et al.  Diagnostic problems in the cytologic evaluation of cerebrospinal fluid for lymphoma and leukemia. , 1981, Acta cytologica.

[194]  P. Kirby.  Rhabdoid meningioma: Intraoperative diagnosis using smear preparation , 2003, Diagnostic cytopathology.

[195]  R. Mervis.  Structural alterations in neurons of aged canine neocortex: A Golgi study , 1978, Experimental Neurology.

[196]  A. Scheibel,et al.  Progressive dendritic changes in aging human cortex , 1975, Experimental Neurology.

[197]  W. Oertel,et al.  Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis. , 2001, Brain : a journal of neurology.

[198]  A. Twijnstra,et al.  Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma , 2002, Cancer.

[199]  E. Richardson,et al.  Diagnosis of cryptococcal meningitis by cytologic methods , 1980, Neurology.

[200]  A. Haleem,et al.  Fine‐needle aspiration biopsy of metastatic chordoma: Case report and review of the literature , 2000, Diagnostic cytopathology.

[201]  Y. Geinisman,et al.  Loss of synapses in the dentate gyrus of the senescent rat. , 1976, The American journal of anatomy.

[202]  W. Szyfelbein,et al.  Lyme disease meningopolyneuritis simulating malignant lymphoma. , 1988, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

[203]  Christos P. Kokkoris.  Leptomeningeal carcinomatosis: How does cancer reach the pia‐arachnoid? , 1983, Cancer.

[204]  W. Feiden,et al.  [Primary CNS lymphomas. Morphology and diagnosis]. , 2002, Der Pathologe.

[205]  M. Sayre,et al.  Cardiopulmonary resuscitation and emergency cardiovascular care. Stroke. , 2001, Annals of emergency medicine.

[206]  Sanford L. Palay,et al.  The fine structure of the nervous system: The neurons and supporting cells , 1976 .

[207]  J. Bennett,et al.  Analysis of multiple sclerosis cerebrospinal fluid reveals a continuum of clonally related antibody-secreting cells that are predominantly plasma blasts , 2007, Journal of Neuroimmunology.

[208]  P. V. Kumar.  Nuclear Grooves in Ependymoma , 1997 .

[209]  A. Peters,et al.  A three dimensional study of layer I of the rat parietal cortex , 1973, The Journal of comparative neurology.

[210]  C. Polman,et al.  Cerebrospinal fluid cells in multiple sclerosis and other neurological diseases: an immunocytochemical study , 2004, Journal of Neurology.

[211]  C E Lucas,et al.  Massive steroids do not reduce the zone of injury after penetrating spinal cord injury. , 1994, The Journal of trauma.

[212]  D. Bok,et al.  Practical Remarks on Gout, Rheumatic Fever, and Chonic Rheumatism of the Joints; Being the Substance of the Croonian Lectures for the Present Year, Delivered at the College of Physicians , 1844, Edinburgh Medical and Surgical Journal.

[213]  W. Greenough,et al.  Subsynaptic plate perforations: changes with age and experience in the rat. , 1978, Science.

[214]  G. Schneider,et al.  Decompressive craniectomy following traumatic brain injury: ICP, CPP and neurological outcome. , 2002, Acta neurochirurgica. Supplement.

[215]  T. Ryken,et al.  Cervical Spine Immobilization before Admission to the Hospital Search Criteria , 2022 .

[216]  H. Kölmel,et al.  Cell count and ratio of helper/inducer to suppressor/cytotoxic T-cells in the cerebrospinal fluid of patients with multiple sclerosis , 1989, Journal of Neurology.

[217]  M. Peng,et al.  Changes in the nuclear volume of rat hypothalamic neurons in old age. , 1976, Neuroendocrinology.

[218]  K. Chuah,et al.  Role of Intraoperative Smear Cytology in the Diagnosis of Anaplastic Oligodendroglioma , 2003, Acta Cytologica.

[219]  I. Nagano,et al.  Melanin-laden macrophages in cerebrospinal fluid in Vogt-Koyanagi-Harada syndrome. , 1996, Archives of ophthalmology.

[220]  L. A. Bates,et al.  Neurotoxicity of Aluminum , 1984 .

[221]  S. Levay,et al.  Synaptic patterns in the visual cortex of the cat and monkey. Electron microscopy of Golgi Preparations , 1973, The Journal of comparative neurology.

[222]  H. Wiśniewski,et al.  Morphology of the aging brain, human and animal. , 1973, Progress in brain research.

[223]  K. Brizzee.  Gross Morphometric Analyses and Quantitative Histology of the Aging Brain , 1975 .

[224]  S. Stein,et al.  Moderate head injury: a guide to initial management. , 1992, Journal of neurosurgery.

[225]  G G Enas,et al.  Improved confidence of outcome prediction in severe head injury. A comparative analysis of the clinical examination, multimodality evoked potentials, CT scanning, and intracranial pressure. , 1981, Journal of neurosurgery.

[226]  P. Timiras,et al.  A comparison of cell populations at various depth levels in cerebral cortex of young adult and aged Long-Evans rats. , 1968, Journal of gerontology.

[227]  J. Ordy,et al.  Early appearance and regional differences in intraneuronal and extraneuronal lipofuscin accumulation with age in the brain of a nonhuman primate (Macaca mulatta). , 1974, Journal of gerontology.