Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by disrupting HDAC2/Sin3A/MeCP2 corepressor complex

[1]  K. Chung,et al.  Abnormal ADAM17 expression causes airway fibrosis in chronic obstructive asthma. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[2]  Chien-Huang Lin,et al.  Histone deacetylase 7 mediates endothelin-1-induced connective tissue growth factor expression in human lung fibroblasts through p300 and activator protein-1 activation , 2021, Journal of Biomedical Science.

[3]  L. Kong,et al.  Identification of histone acetylation in a murine model of allergic asthma by proteomic analysis , 2020, Experimental biology and medicine.

[4]  C. Yao,et al.  Senescence of Alveolar Type 2 Cells Drives Progressive Pulmonary Fibrosis. , 2020, American journal of respiratory and critical care medicine.

[5]  M. Blades,et al.  Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo , 2018, Scientific Reports.

[6]  Chien-Huang Lin,et al.  ADAM17/EGFR‐dependent ERK activation mediates thrombin‐induced CTGF expression in human lung fibroblasts , 2018, Experimental cell research.

[7]  Yau-Huei Wei,et al.  Essential role of connective tissue growth factor (CTGF) in transforming growth factor-β1 (TGF-β1)-induced myofibroblast transdifferentiation from Graves’ orbital fibroblasts , 2018, Scientific Reports.

[8]  Yau-Huei Wei,et al.  Essential role of connective tissue growth factor (CTGF) in transforming growth factor-β1 (TGF-β1)-induced myofibroblast transdifferentiation from Graves’ orbital fibroblasts , 2018, Scientific Reports.

[9]  Chien-Huang Lin,et al.  MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts , 2018, Journal of Biomedical Science.

[10]  Min Zhang,et al.  HDAC2 Suppresses IL17A‐Mediated Airway Remodeling in Human and Experimental Modeling of COPD , 2017, Chest.

[11]  Mingwei Li,et al.  Effects of dynamic changes in histone acetylation and deacetylase activity on pulmonary fibrosis , 2017, International immunopharmacology.

[12]  Chien-Huang Lin,et al.  Hypoxia‐induced ADAM 17 expression is mediated by RSK1‐dependent C/EBP&bgr; activation in human lung fibroblasts , 2017, Molecular immunology.

[13]  I. Fraser,et al.  IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages , 2018, Cell reports.

[14]  Jianlong Wang,et al.  The SIN3A/HDAC Corepressor Complex Functionally Cooperates with NANOG to Promote Pluripotency. , 2017, Cell reports.

[15]  D. Fulton,et al.  Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis , 2017, Front. Immunol..

[16]  M. Bonini,et al.  The role of the small airways in the pathophysiology of asthma and chronic obstructive pulmonary disease , 2015, Therapeutic advances in respiratory disease.

[17]  I. Horváth,et al.  Clinically relevant subgroups in COPD and asthma , 2015, European Respiratory Review.

[18]  Zhizhou Yang,et al.  Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat-induced pulmonary fibrosis , 2015, Molecular medicine reports.

[19]  W. Coward,et al.  A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[20]  L. J. Lee,et al.  Epigenetic regulation of connective tissue growth factor by MicroRNA‐214 delivery in exosomes from mouse or human hepatic stellate cells , 2014, Hepatology.

[21]  L. Gregory,et al.  Endothelin-1 directs airway remodeling and hyper-reactivity in a murine asthma model , 2013, Allergy.

[22]  P. Barnes,et al.  Passive Smoking Impairs Histone Deacetylase-2 in Children With Severe Asthma , 2013, Chest.

[23]  Chien-Huang Lin,et al.  Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by ETAR-dependent JNK/AP-1 pathway. , 2014, Biochemical pharmacology.

[24]  H. Kuo,et al.  The endothelin A receptor mediates fibrocyte differentiation in chronic obstructive asthma. The involvement of connective tissue growth factor. , 2013, American journal of respiratory and critical care medicine.

[25]  J. Davie,et al.  Protein Kinase CK2 Regulates the Dimerization of Histone Deacetylase 1 (HDAC1) and HDAC2 during Mitosis* , 2013, The Journal of Biological Chemistry.

[26]  A. Phillips,et al.  Transforming Growth Factor-β1 (TGF-β1)-stimulated Fibroblast to Myofibroblast Differentiation Is Mediated by Hyaluronan (HA)-facilitated Epidermal Growth Factor Receptor (EGFR) and CD44 Co-localization in Lipid Rafts* , 2013, The Journal of Biological Chemistry.

[27]  G. Verleden,et al.  The pathogenesis of pulmonary fibrosis: a moving target , 2012, European Respiratory Journal.

[28]  K. Lipson,et al.  CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis , 2012, Fibrogenesis & tissue repair.

[29]  Q. Hamid,et al.  Remodeling in asthma. , 2011, The Journal of allergy and clinical immunology.

[30]  Thomas A. Wynn,et al.  Integrating mechanisms of pulmonary fibrosis , 2011, The Journal of experimental medicine.

[31]  Hyung-Seok Kim,et al.  Casein Kinase-2&agr;1 Induces Hypertrophic Response by Phosphorylation of Histone Deacetylase 2 S394 and its Activation in the Heart , 2011, Circulation.

[32]  E. Kavalali,et al.  Role of MeCP2, DNA methylation, and HDACs in regulating synapse function , 2011, Journal of Neurodevelopmental Disorders.

[33]  Richard J Martin,et al.  Inhibition of histone deacetylase 2 expression by elevated glucocorticoid receptor beta in steroid-resistant asthma. , 2010, American journal of respiratory and critical care medicine.

[34]  I. Rahman,et al.  Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes. , 2010, Archives of biochemistry and biophysics.

[35]  K. Brown,et al.  The Role of Endothelin-1 in the Pathogenesis of Idiopathic Pulmonary Fibrosis , 2010, BioDrugs.

[36]  P. Barnes Histone deacetylase-2 and airway disease , 2009, Therapeutic advances in respiratory disease.

[37]  Mei Han,et al.  All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells. , 2009, Biochemical and biophysical research communications.

[38]  D. Abraham,et al.  Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen. , 2009, Arthritis and rheumatism.

[39]  S. Parapuram,et al.  Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease? , 2009, Journal of Cell Communication and Signaling.

[40]  N. Zhong,et al.  Prior SO2 exposure promotes airway inflammation and subepithelial fibrosis following repeated ovalbumin challenge , 2008, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[41]  I. Rahman,et al.  Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD. , 2008, Antioxidants & redox signaling.

[42]  M. Aubier,et al.  Augmented epithelial endothelin-1 expression in refractory asthma. , 2007, The Journal of allergy and clinical immunology.

[43]  I. Adcock,et al.  Impact of protein acetylation in inflammatory lung diseases. , 2007, Pharmacology & therapeutics.

[44]  I. Adcock,et al.  Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression , 2006, The Journal of experimental medicine.

[45]  S. Peters,et al.  Airway remodeling contributes to the progressive loss of lung function in asthma: an overview. , 2005, The Journal of allergy and clinical immunology.

[46]  J. D. Macklis,et al.  Dissecting MECP2 Function in the Central Nervous System , 2005, Journal of child neurology.

[47]  I. Adcock,et al.  Histone acetylation and deacetylation: importance in inflammatory lung diseases , 2005, European Respiratory Journal.

[48]  I. Adcock,et al.  Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma. , 2004, American journal of respiratory and critical care medicine.

[49]  E. Seto,et al.  Regulation of Histone Deacetylase 2 by Protein Kinase CK2* , 2002, The Journal of Biological Chemistry.

[50]  K. Resing,et al.  Phosphatase Inhibition Leads to Histone Deacetylases 1 and 2 Phosphorylation and Disruption of Corepressor Interactions* , 2002, The Journal of Biological Chemistry.

[51]  R. Silver,et al.  Thrombin Differentiates Normal Lung Fibroblasts to a Myofibroblast Phenotype via the Proteolytically Activated Receptor-1 and a Protein Kinase C-dependent Pathway* , 2001, The Journal of Biological Chemistry.

[52]  L. Boulet,et al.  Synergistic action of endothelin (ET)‐1 on the activation of bronchial fibroblast isolated from normal and asthmatic subjects , 2000, International journal of experimental pathology.

[53]  J. Strouboulis,et al.  Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription , 1998, Nature Genetics.

[54]  Stuart L Schreiber,et al.  Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A , 1997, Cell.

[55]  L. Fasano,et al.  Endothelin-1 in idiopathic pulmonary fibrosis. , 1995, Journal of clinical pathology.

[56]  Hong Ping Chen,et al.  Histone deacetylases and mechanisms of regulation of gene expression. , 2015, Critical reviews in oncogenesis.

[57]  I. Darby,et al.  Fibroblast differentiation in wound healing and fibrosis. , 2007, International review of cytology.

[58]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..