Long-term expanding human airway organoids for disease modelling
暂无分享,去创建一个
Jeroen S. van Zon | S. Tans | A. van Oudenaarden | J. V. van Zon | E. Cuppen | H. Clevers | Norman Sachs | E. Smit | A. Lyubimova | J. Korving | H. Begthel | P. Peters | R. Vries | J. de Ligt | E. Voest | F. Weeber | S. Boj | L. Bont | K. Dijkstra | Inha Heo | M. Viveen | F. Coenjaerts | J. Beekman | C. K. van der Ent | E. P. Olimpio | M. V. van Oosterhout | Kuldeep Kumawat | C. van Moorsel | L. Meyaard | L. Böttinger | A. Papaspyropoulos | Dymph Klay | Guizela Huelsz-Prince | D. Z. Zomer-van Ommen | Nino Iakobachvili | M. van der Linden | Sepideh Derakhshan | Luc Teeven | E. Ramos
[1] Laura M. Palermo,et al. A three-dimensional model of human lung development and disease from pluripotent stem cells , 2017, Nature Cell Biology.
[2] B. Hogan,et al. Lung organoids: current uses and future promise , 2017, Development.
[3] V. Gulmans,et al. Intestinal organoids and personalized medicine in cystic fibrosis: a successful patient-oriented research collaboration , 2016, Current opinion in pulmonary medicine.
[4] H. Clevers,et al. Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis , 2016, Science Translational Medicine.
[5] M. Hild,et al. Production of 3-D Airway Organoids From Primary Human Airway Basal Cells and Their Use in High-Throughput Screening. , 2016, Current protocols in stem cell biology.
[6] P. Pauwels,et al. TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value. , 2016, Critical reviews in oncology/hematology.
[7] J. Taylor-Cousar,et al. Lumacaftor and ivacaftor in the management of patients with cystic fibrosis: current evidence and future prospects , 2015, Therapeutic advances in respiratory disease.
[8] L. Bont,et al. Neutrophils in respiratory syncytial virus infection: A target for asthma prevention , 2015, Journal of Allergy and Clinical Immunology.
[9] Hayley E. Francies,et al. Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients , 2015, Cell.
[10] Hans Clevers,et al. Sequential cancer mutations in cultured human intestinal stem cells , 2015, Nature.
[11] Gail H Deutsch,et al. In vitro generation of human pluripotent stem cell derived lung organoids , 2015, eLife.
[12] M. Spector,et al. Organoid Models of Human and Mouse Ductal Pancreatic Cancer , 2015, Cell.
[13] Hans Clevers,et al. Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver , 2015, Cell.
[14] C. Lindskog,et al. The lung‐specific proteome defined by integration of transcriptomics and antibody‐based profiling , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[15] E. Cuppen,et al. Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures , 2014, Cell.
[16] Yang Wang,et al. IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells , 2014, Proceedings of the National Academy of Sciences.
[17] Kwok-Kin Wong,et al. Non-small-cell lung cancers: a heterogeneous set of diseases , 2014, Nature Reviews Cancer.
[18] E. Caci,et al. The TMEM16A chloride channel as an alternative therapeutic target in cystic fibrosis. , 2014, The international journal of biochemistry & cell biology.
[19] P. Collins,et al. RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction. , 2014, The Journal of clinical investigation.
[20] N. Neff,et al. Reconstructing lineage hierarchies of the distal lung epithelium using single cell RNA-seq , 2014, Nature.
[21] Thomas Ferkol,et al. The global burden of respiratory disease. , 2014, Annals of the American Thoracic Society.
[22] W. de Lau,et al. The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength , 2014, Genes & development.
[23] Hans Clevers,et al. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. , 2013, Cell stem cell.
[24] G. Vunjak‐Novakovic,et al. Highly efficient generation of airway and lung epithelial cells from human pluripotent stem cells , 2013, Nature Biotechnology.
[25] George P Patrinos,et al. Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene , 2013, Nature Genetics.
[26] M. Gershwin,et al. Respiratory Syncytial Virus—A Comprehensive Review , 2013, Clinical Reviews in Allergy & Immunology.
[27] J. Rossant,et al. Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein , 2012, Nature Biotechnology.
[28] Abraham J. Koster,et al. Virtual nanoscopy: Generation of ultra-large high resolution electron microscopy maps , 2012, The Journal of cell biology.
[29] Feride Oeztuerk-Winder,et al. The many faces of p38 mitogen-activated protein kinase in progenitor/stem cell differentiation. , 2012, The Biochemical journal.
[30] Hans Clevers,et al. A functional CFTR assay using primary cystic fibrosis intestinal organoids , 2013, Nature Medicine.
[31] J. Mezey,et al. RNA-Seq quantification of the human small airway epithelium transcriptome , 2012, BMC Genomics.
[32] H. Clevers,et al. Controlled gene expression in primary Lgr5 organoid cultures , 2011, Nature Methods.
[33] Hans Clevers,et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. , 2011, Gastroenterology.
[34] A. Verkman,et al. Small‐molecule activators of TMEM16A, a calcium‐activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[35] H. Park,et al. High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice , 2011, PloS one.
[36] R. Crystal,et al. Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome? , 2011, American journal of respiratory cell and molecular biology.
[37] Herren Wu,et al. Respiratory Syncytial Virus-Neutralizing Monoclonal Antibodies Motavizumab and Palivizumab Inhibit Fusion , 2010, Journal of Virology.
[38] Scott H. Randell,et al. Basal cells as stem cells of the mouse trachea and human airway epithelium , 2009, Proceedings of the National Academy of Sciences.
[39] R. Garofalo,et al. Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virus. , 2006, American journal of respiratory cell and molecular biology.
[40] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[41] Michael J. Holtzman,et al. Respiratory Syncytial Virus Nonstructural Proteins NS1 and NS2 Mediate Inhibition of Stat2 Expression and Alpha/Beta Interferon Responsiveness , 2005, Journal of Virology.
[42] L. Vassilev,et al. In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2 , 2004, Science.
[43] M. Daly,et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes , 2003, Nature Genetics.
[44] F. Ratjen,et al. Cystic fibrosis , 2003, The Lancet.
[45] W. Kuis,et al. Simultaneous Detection of 15 Human Cytokines in a Single Sample of Stimulated Peripheral Blood Mononuclear Cells , 2003, Clinical Diagnostic Laboratory Immunology.
[46] P. Collins,et al. Iduronic acid-containing glycosaminoglycans on target cells are required for efficient respiratory syncytial virus infection. , 2000, Virology.
[47] P. Collins,et al. Altered Growth Characteristics of Recombinant Respiratory Syncytial Viruses Which Do Not Produce NS2 Protein , 1999, Journal of Virology.
[48] J. Klossek,et al. Tubule formation by human surface respiratory epithelial cells cultured in a three-dimensional collagen lattice. , 1993, The American journal of physiology.
[49] Q. Tan,et al. Human airway organoid engineering as a step toward lung regeneration and disease modeling. , 2017, Biomaterials.
[50] S. Madhi,et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. , 2010, Lancet.
[51] J. J. M. Linders,et al. Wet medisch-wetenschappelijk onderzoek met mensen , 2010 .
[52] Scott H Randell,et al. Well-differentiated human airway epithelial cell cultures. , 2005, Methods in molecular medicine.