Self-sorting of isotropic cells.

Abstract In the preceding paper (Goel et al., 1970), using a simple model which assumes (a) differential affinities between cells of different types, and, (b) local motility of cells, it was shown that, for a self-sorting system of isotropic cells, none of the absolutely stable configurations are the two-dimensional analogs of biologically interesting structures, e.g. tubular, epithelial and vesicular. Using the same model, it is shown here that some of the absolutely stable configurations for the two-dimensional anisotropic cells are the analogs of these biologically interesting structures.