Pilomyxoid astrocytoma showing malignant transformation in adult male

Pilomyxoid astrocytomas are type of tumors rarely seen in the central nervous system as a variant of pilocytic astrocytoma. They are often localized in hypothalamic-chiasmatic area and seen in early childhood. They exhibit different histological characteristics and more aggressive behaviors compared to pilocytic astrocytomas. Although cases with malignant transformation were reported in pilocytic astrocytomas, no pilomyxoid astrocytoma patients was reported with malignant transformation. We have presented a pilomyxoid astrocytoma patient, since it is rarely seen in adulthood and shows malignant transformation histopathologically.

[1]  M. Fowkes,et al.  Pilomyxoid astrocytoma of the cerebellar vermis in an elderly patient , 2014, Surgical neurology international.

[2]  S. Chakraborti,et al.  Pilomyxoid astrocytoma with high proliferation index , 2013, Journal of pediatric neurosciences.

[3]  I. Jusué-Torres,et al.  [Leptomeningeal spread of an intramedullary cervical pilocytic astrocytoma: case report and literature review]. , 2011, Neurocirugia.

[4]  T. Kawaguchi,et al.  Pilocytic astrocytoma with histological malignant features without previous radiation therapy--case report. , 2011, Neurologia medico-chirurgica.

[5]  M. Rosenblum,et al.  Spectrum of Pilomyxoid Astrocytomas: Intermediate Pilomyxoid Tumors , 2010, The American journal of surgical pathology.

[6]  B. Scheithauer,et al.  Anaplasia in Pilocytic Astrocytoma Predicts Aggressive Behavior , 2010, The American journal of surgical pathology.

[7]  C. Fuller,et al.  Pilocytic Astrocytoma and Pilomyxoid Astrocytoma , 2010 .

[8]  H. Tsuda,et al.  Pilomyxoid astrocytoma of the fourth ventricle in an adult , 2008, Acta Neurochirurgica.

[9]  R. Janzer,et al.  Pilomyxoid astrocytoma of the spinal cord in an adult , 2008, Acta Neurochirurgica.

[10]  C. Parsa,et al.  Juvenile pilocytic astrocytomas do not undergo spontaneous malignant transformation: grounds for designation as hamartomas , 2007, British Journal of Ophthalmology.

[11]  R. Jain,et al.  Spinal Cord Pilomyxoid Astrocytoma: An Unusual Tumor , 2007, Journal of neuroimaging : official journal of the American Society of Neuroimaging.

[12]  J. Kros,et al.  Radiotherapy plus concomitant and adjuvant temozolomide for leptomeningeal pilomyxoid astrocytoma: a case study , 2006, Journal of Neuro-Oncology.

[13]  J. Mocco,et al.  Astrocytoma with pilomyxoid features presenting in an adult , 2006, Neuropathology : official journal of the Japanese Society of Neuropathology.

[14]  J. Mocco,et al.  Pilomyxoid astrocytoma: diagnosis, prognosis, and management. , 2005, Neurosurgical focus.

[15]  J. Mocco,et al.  Pilomyxoid astrocytoma: a review. , 2004, MedGenMed : Medscape general medicine.

[16]  A. Olivi,et al.  Pilocytic and Pilomyxoid Hypothalamic/Chiasmatic Astrocytomas , 2004, Neurosurgery.

[17]  S. Hajdu Pilocytic Astrocytoma , 2004, Acta Cytologica.

[18]  W. Couldwell,et al.  Spontaneous hemorrhage associated with a pilomyxoid astrocytoma. Case report. , 2003, Journal of neurosurgery.

[19]  S. Landas,et al.  Suprasellar monomorphous pilomyxoid neoplasm: an ultastructural analysis. , 2001, Clinical neuropathology.

[20]  P. Burger,et al.  Pediatric astrocytomas with monomorphous pilomyxoid features and a less favorable outcome. , 1999, Journal of neuropathology and experimental neurology.

[21]  B. Scheithauer,et al.  Cellular proliferation in pilocytic and diffuse astrocytomas. , 1999, Journal of neuropathology and experimental neurology.

[22]  D. Cohen,et al.  Central nervous system tumors in children , 1991 .

[23]  P. Mckeever,et al.  Cerebral pilocytic astrocytoma , 1985, Cancer.

[24]  G. Dohrmann,et al.  Central nervous system tumors in children cns tumors in children , 1977, Cancer.