Does nitric oxide modulate mitochondrial energy generation and apoptosis?

[1]  G. Semenza,et al.  Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O 2 tension , 2002 .

[2]  S. Moncada,et al.  Different responses of astrocytes and neurons to nitric oxide: The role of glycolytically generated ATP in astrocyte protection , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[3]  E. Clementi,et al.  Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation. , 2001, The Biochemical journal.

[4]  J. Haddad,et al.  A non‐hypoxic, ROS‐sensitive pathway mediates TNF‐α‐dependent regulation of HIF‐1α , 2001 .

[5]  B. Trimmer,et al.  Nitric Oxide and the Control of Firefly Flashing , 2001, Science.

[6]  M. Sporn,et al.  A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines. , 2001, Arthritis and rheumatism.

[7]  Á. Almeida,et al.  A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons , 2001, Journal of neurochemistry.

[8]  Xiaoping Liu,et al.  The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[9]  C. Cooper,et al.  Nitric oxide synthases: structure, function and inhibition. , 2001, The Biochemical journal.

[10]  S Moncada,et al.  The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[11]  R. Johns,et al.  Normoxic stabilization of hypoxia-inducible factor-1 expression and activity: redox-dependent effect of nitrogen oxides. , 2000, Molecular pharmacology.

[12]  N. Chandel,et al.  Reactive Oxygen Species Generated at Mitochondrial Complex III Stabilize Hypoxia-inducible Factor-1α during Hypoxia , 2000, The Journal of Biological Chemistry.

[13]  B. Freeman,et al.  Cytochrome c Nitration by Peroxynitrite* , 2000, The Journal of Biological Chemistry.

[14]  E. Cadenas,et al.  Estimation of H2O2 gradients across biomembranes , 2000, FEBS letters.

[15]  H. Akil,et al.  Direct evidence of nitric oxide presence within mitochondria. , 2000, Biochemical and biophysical research communications.

[16]  J Garthwaite,et al.  Rapid desensitization of the nitric oxide receptor, soluble guanylyl cyclase, underlies diversity of cellular cGMP responses. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[17]  E. Clementi,et al.  Oxidative stress and S‐nitrosylation of proteins in cells , 2000, British journal of pharmacology.

[18]  M. Makuuchi,et al.  Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide. , 2000, Blood.

[19]  A. Álvarez,et al.  Nitric oxide induces tyrosine nitration and release of cytochrome c preceding an increase of mitochondrial transmembrane potential in macrophages , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[20]  P. Huang,et al.  Ultrastructural localization of neuronal nitric oxide synthase in the laterodorsal tegmental nucleus of wild-type and knockout mice , 1999, Neuroscience.

[21]  P. Mcconnell,et al.  Endogenous endothelial nitric oxide synthase-derived nitric oxide is a physiological regulator of myocardial oxygen consumption. , 1999, Circulation research.

[22]  M. Goldberg,et al.  Inhibition of Hypoxia-inducible Factor 1 Activation by Carbon Monoxide and Nitric Oxide , 1999, The Journal of Biological Chemistry.

[23]  E. Clementi,et al.  On the mechanism by which vascular endothelial cells regulate their oxygen consumption. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[24]  S. Moncada,et al.  Transcellular regulation of cell respiration by nitric oxide generated by activated macrophages , 1998, FEBS letters.

[25]  H. Ischiropoulos.  Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. , 1998, Archives of biochemistry and biophysics.

[26]  E. Clementi,et al.  Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[27]  C. Giulivi,et al.  Functional implications of nitric oxide produced by mitochondria in mitochondrial metabolism. , 1998, The Biochemical journal.

[28]  S. Moncada,et al.  Nitric oxide and the haemodynamic profile of endotoxin shock in the conscious mouse , 1998, British journal of pharmacology.

[29]  S. Cuzzocrea,et al.  Oxidation, tyrosine nitration and cytostasis induction in the absence of inducible nitric oxide synthase. , 1998, International journal of molecular medicine.

[30]  C. Giulivi,et al.  Production of Nitric Oxide by Mitochondria* , 1998, The Journal of Biological Chemistry.

[31]  C. Giulivi,et al.  Purification and Characterization of a Nitric-oxide Synthase from Rat Liver Mitochondria* , 1998, The Journal of Biological Chemistry.

[32]  C. Richter,et al.  Nitric oxide synthase activity in mitochondria , 1997, FEBS letters.

[33]  A. Halestrap,et al.  Oxidative Stress, Thiol Reagents, and Membrane Potential Modulate the Mitochondrial Permeability Transition by Affecting Nucleotide Binding to the Adenine Nucleotide Translocase* , 1997, The Journal of Biological Chemistry.

[34]  M. Brunori,et al.  On the Mechanism of Inhibition of Cytochrome c Oxidase by Nitric Oxide* , 1996, The Journal of Biological Chemistry.

[35]  M. Murphy,et al.  Superoxide production by mitochondria in the presence of nitric oxide forms peroxynitrite , 1996, Biochemistry and molecular biology international.

[36]  G. Semenza,et al.  Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. , 1996, The American journal of physiology.

[37]  N. Chandel,et al.  Molecular Oxygen Modulates Cytochrome c Oxidase Function* , 1996, The Journal of Biological Chemistry.

[38]  P. R. Miles,et al.  Nitric oxide alters metabolism in isolated alveolar type II cells. , 1996, The American journal of physiology.

[39]  J. Poderoso,et al.  Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles. , 1996, Archives of biochemistry and biophysics.

[40]  M. A. Moro,et al.  Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose. , 1996, The Biochemical journal.

[41]  J. Voorhees,et al.  Molecular basis of sun-induced premature skin ageing and retinoid antagonism , 1996, Nature.

[42]  J. Bolaños,et al.  Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione. , 1996, Free radical biology & medicine.

[43]  T. Hintze,et al.  Nitric oxide. An important signaling mechanism between vascular endothelium and parenchymal cells in the regulation of oxygen consumption. , 1995, Circulation.

[44]  M. Wilson,et al.  Inhibition of cytochrome c oxidase in turnover by nitric oxide: mechanism and implications for control of respiration. , 1995, The Biochemical journal.

[45]  G. Burnstock,et al.  Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. , 1995, Biochemical and biophysical research communications.

[46]  J. Stamler,et al.  Endothelial type nitric oxide synthase in skeletal muscle fibers: mitochondrial relationships. , 1995, Biochemical and biophysical research communications.

[47]  P Rhodes,et al.  Roles of nitric oxide in tumor growth. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[48]  C. Cooper,et al.  Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase , 1994, FEBS letters.

[49]  J. Wood,et al.  Models of the diffusional spread of nitric oxide: Implications for neural nitric oxide signalling and its pharmacological properties , 1994, Neuropharmacology.

[50]  C. Richter,et al.  Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension. , 1994, Biochemical and biophysical research communications.

[51]  M. Schaefer,et al.  Low Molecular Weight Inhibitors in Corneal Ulceration a , 1994, Annals of the New York Academy of Sciences.

[52]  M. A. Moro,et al.  Paradoxical fate and biological action of peroxynitrite on human platelets. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[53]  S. Moncada,et al.  Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide , 1994, FEBS letters.

[54]  A. Quyyumi,et al.  Complexes of Nitric Oxide with Nucleophiles as Agents for the Controlled Biological Release of Nitric Oxide: Hemodynamic Effect in the Rabbit , 1993, Journal of cardiovascular pharmacology.

[55]  P Tomboulian,et al.  Diffusion of nitric oxide in the aorta wall monitored in situ by porphyrinic microsensors. , 1993, Biochemical and biophysical research communications.

[56]  D. Wink,et al.  Complexes of .NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. , 1991, Journal of medicinal chemistry.

[57]  S. Moncada,et al.  Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.

[58]  B. Freeman,et al.  Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. , 1991, The Journal of biological chemistry.

[59]  K. Shibuki,et al.  Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum , 1991, Nature.

[60]  B. Freeman,et al.  Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[61]  S. Moncada,et al.  Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion. , 1989, The Biochemical journal.

[62]  R. Busse,et al.  Hypoxia stimulates release of endothelium-derived relaxant factor. , 1989, The American journal of physiology.

[63]  S Nioka,et al.  In vivo study of tissue oxygen metabolism using optical and nuclear magnetic resonance spectroscopies. , 1989, Annual review of physiology.

[64]  S. Moncada,et al.  Vascular endothelial cells synthesize nitric oxide from L-arginine , 1988, Nature.

[65]  S. Moncada,et al.  Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor , 1987, Nature.

[66]  M. Brand,et al.  CONTROL OF ELECTRON FLUX THROUGH THE RESPIRATORY CHAIN IN MITOCHONDRIA AND CELLS , 1987, Biological reviews of the Cambridge Philosophical Society.

[67]  S. Moncada,et al.  Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor , 1986, Nature.

[68]  J. Crapo,et al.  Hyperoxia increases H2O2 release by lung mitochondria and microsomes. , 1982, Archives of biochemistry and biophysics.

[69]  R. Furchgott,et al.  The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine , 1980, Nature.

[70]  J. Turrens,et al.  Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. , 1980, The Biochemical journal.

[71]  E. Cadenas,et al.  Role of ubiquinone in the mitochondrial generation of hydrogen peroxide. , 1976, The Biochemical journal.

[72]  B Chance,et al.  The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. , 1973, The Biochemical journal.

[73]  Wainio Ww.  Reactions of cytochrome oxidase. , 1955 .

[74]  W. Wainio.  Reactions of cytochrome oxidase. , 1955, The Journal of biological chemistry.