Thoracoscopic Versus Open Congenital Diaphragmatic Hernia Repair: Single Tertiary Center Review.

BACKGROUND Congenital diaphragmatic hernia (CDH) can be repaired open or through thoracoscopy. Thoracoscopic CDH repair could improve cosmesis and avoid the complications of laparotomy, but may have higher recurrence rates. The purpose of this study was to examine the outcomes of thoracoscopic versus open CDH repair, with regard to recurrence, perioperative parameters, and postoperative complications. METHODS We performed a retrospective review of open versus thoracoscopic CDH repairs over an 8.5-year period. The primary outcome was hernia recurrence. Secondary outcomes included intraoperative partial pressure of carbon dioxide (pCO2) levels, length of stay, and postoperative complications. All statistical analyses were performed using standard statistical methods. RESULTS A total of 54 infants underwent CDH repair during the study period, of whom 25 underwent successful thoracoscopic repair. Two patients who had undergone open repair developed recurrent diaphragmatic hernias (recurrence rate 3.7%). Operative time and intraoperative pCO2 levels did not differ between groups. Length of stay was shorter in the thoracoscopic cohort. Four patients in the open cohort developed ventral hernias and five developed bowel obstructions during follow-up. No long-term complications were identified in the thoracoscopic cohort. The median follow-up was 27 months. CONCLUSIONS In our experience, thoracoscopic CDH repair was performed safely and with similar outcomes compared to open repair. In addition to improved cosmesis, thoracoscopic repair may avoid some of the long-term complications of laparotomy. In our series, none of the thoracoscopic CDH repairs recurred. We conclude that thoracoscopic CDH repair is a safe and appropriate technique for select neonates.

[1]  M. Harting,et al.  The Congenital Diaphragmatic Hernia Study Group registry update. , 2014, Seminars in fetal & neonatal medicine.

[2]  S. Eaton,et al.  Hypercapnia and Acidosis During Open and Thoracoscopic Repair of Congenital Diaphragmatic Hernia and Esophageal Atresia: Results of a Pilot Randomized Controlled Trial , 2013, Annals of surgery.

[3]  D. Kays,et al.  Long-term Maturation of Congenital Diaphragmatic Hernia Treatment Results: Toward Development of a Severity-Specific Treatment Algorithm , 2013, Annals of surgery.

[4]  W. Chung,et al.  Developmental outcomes of children with congenital diaphragmatic hernia: a multicenter prospective study. , 2013, Journal of pediatric surgery.

[5]  A. Yamataka,et al.  Surgical intervention for congenital diaphragmatic hernia: open versus thoracoscopic surgery , 2013, Pediatric Surgery International.

[6]  P. Kuhn,et al.  Congenital diaphragmatic hernia: an evaluation of risk factors for failure of thoracoscopic primary repair in neonates. , 2013, Journal of pediatric surgery.

[7]  M. Zamakhshary,et al.  Thoracoscopic repair of neonatal congenital diaphragmatic hernia (CDH): outcomes after a systematic quality improvement process. , 2013, Journal of pediatric surgery.

[8]  Jason C. Fisher,et al.  Early recurrence of congenital diaphragmatic hernia is higher after thoracoscopic than open repair: a single institutional study. , 2011, Journal of pediatric surgery.

[9]  KuoJen Tsao,et al.  Minimally invasive repair of congenital diaphragmatic hernia. , 2011, Journal of pediatric surgery.

[10]  E. Jesudason,et al.  Neonatal Endosurgical Congenital Diaphragmatic Hernia Repair: A Systematic Review and Meta-Analysis , 2010, Annals of surgery.

[11]  D. Tibboel,et al.  Thoracoscopic repair in congenital diaphragmatic hernia: patching is safe and reduces the recurrence rate. , 2010, Journal of pediatric surgery.

[12]  S. Eaton,et al.  Thoracoscopic repair of congenital diaphragmatic hernia: intraoperative ventilation and recurrence. , 2010, Journal of pediatric surgery.

[13]  L. Cassidy,et al.  Beyond feasibility: a comparison of newborns undergoing thoracoscopic and open repair of congenital diaphragmatic hernias. , 2009, Journal of pediatric surgery.

[14]  M. Zamakhshary,et al.  Physiologic predictors for the need for patch closure in neonatal congenital diaphragmatic hernia , 2008, Pediatric Surgery International.

[15]  Sidney M. Johnson,et al.  Neonatal thoracoscopic repair of congenital diaphragmatic hernia: selection criteria for successful outcome. , 2005, Journal of pediatric surgery.

[16]  D. Teitelbaum,et al.  Early experience with minimally invasive repair of congenital diaphragmatic hernias: results and lessons learned. , 2003, Journal of pediatric surgery.

[17]  M. Silen,et al.  Video-assisted thoracic surgical repair of a foramen of Bochdalek hernia. , 1995, The Annals of thoracic surgery.

[18]  S. OsvaldoValdano,et al.  [Congenital diaphragmatic hernias]. , 1954, Prensa medica argentina.

[19]  S. Krishnaswami,et al.  Analysis of 29 consecutive thoracoscopic repairs of congenital diaphragmatic hernia in neonates compared to historical controls. , 2009, Journal of pediatric surgery.

[20]  T. Kane,et al.  Minimally invasive congenital diaphragmatic hernia repair: a 7-year review of one institution’s experience , 2008, Surgical Endoscopy.