Radiation in medicine: Origins, risks and aspirations

The use of radiation in medicine is now pervasive and routine. From their crude beginnings 100 years ago, diagnostic radiology, nuclear medicine and radiation therapy have all evolved into advanced techniques, and are regarded as essential tools across all branches and specialties of medicine. The inherent properties of ionizing radiation provide many benefits, but can also cause potential harm. Its use within medical practice thus involves an informed judgment regarding the risk/benefit ratio. This judgment requires not only medical knowledge, but also an understanding of radiation itself. This work provides a global perspective on radiation risks, exposure and mitigation strategies.

[1]  R. Zeman,et al.  Diagnostic reference levels from the ACR CT Accreditation Program. , 2011, Journal of the American College of Radiology : JACR.

[2]  A S Brody,et al.  Minimizing radiation dose for pediatric body applications of single-detector helical CT: strategies at a large Children's Hospital. , 2001, AJR. American journal of roentgenology.

[3]  E. Rutherford,et al.  The scattering of alpha and beta particles by matter and the structure of the atom , 1911 .

[4]  William G. Lynch,et al.  Introductory Nuclear Physics , 1955 .

[5]  O. Glasser W. C. Roentgen and the discovery of the Roentgen rays. , 1995, AJR. American journal of roentgenology.

[6]  Thorsten Feiweier,et al.  In vivo diffusion tensor MRI of the human heart: Reproducibility of breath‐hold and navigator‐based approaches , 2013, Magnetic resonance in medicine.

[7]  Martin J Yaffe,et al.  Reference values for diagnostic radiology: application and impact. , 2005, Radiology.

[8]  Cynthia H McCollough,et al.  Managing radiation use in medical imaging: a multifaceted challenge. , 2011, Radiology.

[9]  D. Christensen,et al.  Ionizing radiation injuries and illnesses. , 2014, Emergency medicine clinics of North America.

[10]  N. Hamada,et al.  Classification of radiation effects for dose limitation purposes: history, current situation and future prospects , 2014, Journal of radiation research.

[11]  G. W. Barendsen,et al.  RESPONSES OF CULTURED CELLS, TUMOURS, AND NORMAL TISSUES TO RADIATIONS OF DIFFERENT LINEAR ENERGY TRANSFER. , 1968 .

[12]  J H Hendry,et al.  ICRP PUBLICATION 118: ICRP Statement on Tissue Reactions and Early and Late Effects of Radiation in Normal Tissues and Organs — Threshold Doses for Tissue Reactions in a Radiation Protection Context , 2012, Annals of the ICRP.

[13]  J. Fowler,et al.  Effects of different ionizing radiations on human cells in tissue culture. III. Experiments with cyclotron-accelerated alpha-particles and deuterons. , 1963, Radiation research.

[14]  J. Hendry Radiation biology and radiation protection , 2012, Annals of the ICRP.

[15]  J. Timins Communication of benefits and risks of medical radiation: a historical perspective. , 2011, Health physics.

[16]  C. Bartolozzi,et al.  Optimizing the balance between radiation dose and image quality in pediatric head CT: findings before and after intensive radiologic staff training. , 2014, AJR. American journal of roentgenology.

[17]  E. Magiorkinis,et al.  The contribution of Maria Sklodowska-Curie and Pierre Curie to Nuclear and Medical Physics. A hundred and ten years after the discovery of radium. , 2008, Hellenic journal of nuclear medicine.

[18]  D. Brenner,et al.  Estimated risks of radiation-induced fatal cancer from pediatric CT. , 2001, AJR. American journal of roentgenology.

[19]  Jennifer Keegan,et al.  High‐resolution 3D coronary vessel wall imaging with near 100% respiratory efficiency using epicardial fat tracking: Reproducibility and comparison with standard methods , 2011, Journal of magnetic resonance imaging : JMRI.

[20]  Cynthia H McCollough,et al.  Radiation dose to the fetus for pregnant patients undergoing multidetector CT imaging: Monte Carlo simulations estimating fetal dose for a range of gestational age and patient size. , 2008, Radiology.

[21]  H. Khoury,et al.  Organ doses and risks of computed tomography examinations in Recife, Brazil , 2012, Journal of radiological protection : official journal of the Society for Radiological Protection.

[22]  Walter Huda,et al.  Radiation Risk to Children From Computed Tomography , 2007, Pediatrics.

[23]  E. Gadioli,et al.  Introductory Nuclear Physics , 1997 .

[24]  Claude Nahmias,et al.  Radiation Risk to Children From Computed Tomography , 2008, Pediatrics.

[25]  Norbert Magnussen Astroparticle Physics , 1999 .

[26]  W. Dörr [Radiation effect in normal tissue - principles of damage and protection]. , 2010, Nuklearmedizin. Nuclear medicine.

[27]  G. Barendsen Effects of Different Ionizing Radiations on Human , 2016 .

[28]  A. Reed The history of radiation use in medicine. , 2011, Journal of vascular surgery.

[29]  R L Wesenberg,et al.  Fluoroscopy in children: low-exposure technology. , 1984, Radiology.

[30]  P C Goodman,et al.  The new light: discovery and introduction of the X-ray. , 1995, AJR. American journal of roentgenology.

[31]  E. R. M. B.Sc. VIII. Uranium radiation and the electrical conduction produced by it , 2009 .

[32]  Yoh Iwasa,et al.  Evolutionary Branching in a Finite Population: Deterministic Branching vs. Stochastic Branching , 2013, Genetics.

[33]  Walter Huda,et al.  Patient radiation doses from adult and pediatric CT. , 2007, AJR. American journal of roentgenology.

[34]  Mahadevappa Mahesh,et al.  Radiation Dose Management for Fluoroscopically Guided Interventional Medical Procedures , 2012 .