Antiangiogenic compounds: well-established drugs versus emerging natural molecules.

[1]  Ramucirumab , 2020, Reactions Weekly.

[2]  R. Huddleston Structure , 2018, Jane Austen's Style.

[3]  R. Ciampi,et al.  Targeted Therapy in Thyroid Cancer: State of the Art. , 2017, Clinical oncology (Royal College of Radiologists (Great Britain)).

[4]  M. Filla,et al.  The role of integrins in glaucoma , 2017, Experimental eye research.

[5]  D. Iacopetta,et al.  Old Drug Scaffold, New Activity: Thalidomide‐Correlated Compounds Exert Different Effects on Breast Cancer Cell Growth and Progression , 2017, ChemMedChem.

[6]  V. Grünwald,et al.  Cabozantinib: an Active Novel Multikinase Inhibitor in Renal Cell Carcinoma , 2017, Current Oncology Reports.

[7]  Yitao Ding,et al.  Lenalidomide induces apoptosis and inhibits angiogenesis via caspase‑3 and VEGF in hepatocellular carcinoma cells. , 2016, Molecular medicine reports.

[8]  L. Zhu,et al.  Vegfa signals through ERK to promote angiogenesis, but not artery differentiation , 2016, Development.

[9]  S. Basu,et al.  Plants and their active compounds: natural molecules to target angiogenesis , 2016, Angiogenesis.

[10]  T David,et al.  The role of nitric oxide in neurovascular coupling. , 2016, Journal of theoretical biology.

[11]  L. Postovit,et al.  Nitric oxide signaling in human ovarian cancer: A potential therapeutic target. , 2016, Nitric oxide : biology and chemistry.

[12]  Qiu Sun,et al.  Natural Phenolic Metabolites with anti‐Angiogenic Properties — A Review from the Chemical Point of View , 2016 .

[13]  M. Wielechowska,et al.  Synthesis of novel polybrominated benzimidazole derivatives-potential CK2 inhibitors with anticancer and proapoptotic activity. , 2016, Bioorganic & medicinal chemistry.

[14]  Tusharkanti Ghosh,et al.  Role of cox-2 mediated neuroinflammation on the neurodegeneration and cognitive impairments in colchicine induced rat model of Alzheimer's Disease , 2016, Journal of Neuroimmunology.

[15]  Jian Ding,et al.  Design, synthesis and biological evaluation of biphenylurea derivatives as VEGFR-2 kinase inhibitors (II) , 2016 .

[16]  Jeong-Woo Park,et al.  Regulation of Protein Kinase CK2 Catalytic Activity by Protein Kinase C and Phospholipase D2 , 2016, Biochimie.

[17]  Ana Maria Carvalho,et al.  Wild Roman chamomile extracts and phenolic compounds: enzymatic assays and molecular modelling studies with VEGFR-2 tyrosine kinase. , 2016, Food & function.

[18]  H. Chung,et al.  Potent anti-angiogenic component in Croton crassifolius and its mechanism of action. , 2015, Journal of ethnopharmacology.

[19]  A. Azmi,et al.  Broad targeting of angiogenesis for cancer prevention and therapy , 2015, Seminars in cancer biology.

[20]  M. Chawla-Sarkar,et al.  Hsp90/Cdc37 assembly modulates TGFβ receptor-II to act as a profibrotic regulator of TGFβ signaling during cardiac hypertrophy. , 2015, Cellular signalling.

[21]  D. Hinton,et al.  SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization. , 2015, Cytokine.

[22]  Yunchao Su,et al.  The critical role of Akt in cardiovascular function. , 2015, Vascular pharmacology.

[23]  Jingbo Liu,et al.  Natural plant flavonoid apigenin directly disrupts Hsp90/Cdc37 complex and inhibits pancreatic cancer cell growth and migration , 2015 .

[24]  T. Behl,et al.  Possible role of endostatin in the antiangiogenic therapy of diabetic retinopathy. , 2015, Life sciences.

[25]  P. Reddanna,et al.  Structure Based Library Design (SBLD) for new 1,4-dihydropyrimidine scaffold as simultaneous COX-1/COX-2 and 5-LOX inhibitors. , 2015, Bioorganic & medicinal chemistry.

[26]  P. Cheung,et al.  Antioxidant and anti-angiogenic effects of mushroom phenolics-rich fractions , 2015 .

[27]  Xuejiao Liu,et al.  Piperlongumine selectively suppresses ABC-DLBCL through inhibition of NF-κB p65 subunit nuclear import. , 2015, Biochemical and biophysical research communications.

[28]  A. Dimoglo,et al.  The study of dual COX-2/5-LOX inhibitors by using electronic-topological approach based on data on the ligand-receptor interactions. , 2015, Journal of molecular graphics & modelling.

[29]  Shibing Wang,et al.  Anti-angiogenesis or pro-angiogenesis for cancer treatment: focus on drug distribution. , 2015, International journal of clinical and experimental medicine.

[30]  Jeong Ah Kim,et al.  Cytotoxic and anti-angiogenic effects of lanostane triterpenoids from Ganoderma lucidum , 2015 .

[31]  Lihong Hu,et al.  Synthesis and structure-activity relationships of boswellic acid derivatives as potent VEGFR-2 inhibitors. , 2015, Bioorganic & medicinal chemistry.

[32]  M. Mandal,et al.  Oxidative stress triggered by naturally occurring flavone apigenin results in senescence and chemotherapeutic effect in human colorectal cancer cells , 2015, Redox biology.

[33]  J. Burgess,et al.  Asthma is not only an airway disease, but also a vascular disease. , 2015, Pharmacology & therapeutics.

[34]  J. Heilmann,et al.  Natural phenolic metabolites with anti-angiogenic properties – a review from the chemical point of view , 2015, Beilstein journal of organic chemistry.

[35]  N. Ferrara,et al.  Inhibition of protein kinase C enhances angiogenesis induced by platelet-derived growth factor C in hyperglycemic endothelial cells , 2015, Cardiovascular Diabetology.

[36]  Lin Zhao,et al.  Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs , 2015, Oncotarget.

[37]  P. Su,et al.  Discovery of novel VEGFR-2 inhibitors. Part II: biphenyl urea incorporated with salicylaldoxime. , 2015, European journal of medicinal chemistry.

[38]  D. Pennington,et al.  Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease. , 2014, Biochimica et biophysica acta.

[39]  M. Ragunathan,et al.  Iconography : Effect of genistein on regenerative angiogenesis using zebrafish as model organism , 2014 .

[40]  Navjot Shah,et al.  Withanone-Rich Combination of Ashwagandha Withanolides Restricts Metastasis and Angiogenesis through hnRNP-K , 2014, Molecular Cancer Therapeutics.

[41]  Ting-Ting Wu,et al.  Discovery of N-(2-phenyl-1H-benzo[d]imidazol-5-yl)quinolin-4-amine derivatives as novel VEGFR-2 kinase inhibitors. , 2014, European journal of medicinal chemistry.

[42]  E. Chu,et al.  Sequencing of antiangiogenic agents in the treatment of metastatic colorectal cancer. , 2014, Clinical colorectal cancer.

[43]  Jun Peng,et al.  Total Alkaloids of Rubus alceifolius Poir Shows Anti-Angiogenic Activity In Vivo and In Vitro , 2014, Integrative cancer therapies.

[44]  R. Miri,et al.  Ab-initio and Conformational Analysis of a Potent VEGFR-2 Inhibitor: A Case Study on Motesanib , 2014, Iranian journal of pharmaceutical research : IJPR.

[45]  S. Indraccolo,et al.  Metabolic effects of antiangiogenic drugs in tumors: therapeutic implications. , 2014, Biochemical pharmacology.

[46]  Jim Euchner Design , 2014, Catalysis from A to Z.

[47]  L. Attardi,et al.  Unravelling mechanisms of p53-mediated tumour suppression , 2014, Nature Reviews Cancer.

[48]  Yitao Wang,et al.  Erratum to: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation , 2014, AAPS PharmSciTech.

[49]  Y. Carmi,et al.  The role IL-1 in tumor-mediated angiogenesis , 2014, Front. Physiol..

[50]  M. Montenarh Protein kinase CK2 and angiogenesis. , 2014, Advances in clinical and experimental medicine : official organ Wroclaw Medical University.

[51]  J. Montero,et al.  Antiangiogenic activity of neutral lipids, glycolipids, and phospholipids fractions of Pinus halepensis Mill. seeds , 2014 .

[52]  Yuncong C. Li,et al.  Inhibitory effects of quercetin on angiogenesis in larval zebrafish and human umbilical vein endothelial cells. , 2014, European journal of pharmacology.

[53]  F. Totzke,et al.  Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors. , 2014, European journal of medicinal chemistry.

[54]  P. Bie,et al.  Apigenin potentiates the growth inhibitory effects by IKK-β-mediated NF-κB activation in pancreatic cancer cells. , 2014, Toxicology letters.

[55]  K. Szewczyk,et al.  Synergistic interactions between anticancer chemotherapeutics and phenolic compounds and anticancer synergy between polyphenols. , 2014, Postepy higieny i medycyny doswiadczalnej.

[56]  A. Moss The angiopoietin:Tie 2 interaction: a potential target for future therapies in human vascular disease. , 2013, Cytokine & growth factor reviews.

[57]  A. Alhaider,et al.  Punarnavine, an alkaloid from Boerhaavia diffusa exhibits anti-angiogenic activity via downregulation of VEGF in vitro and in vivo. , 2013, Chemico-biological interactions.

[58]  Q. Gao,et al.  The antiangiogenic activity of Kushecarpin D, a novel flavonoid isolated from Sophora flavescens Ait. , 2013, Life sciences.

[59]  N. Yusoff,et al.  Anti-angiogenic quassinoid-rich fraction from Eurycoma longifolia modulates endothelial cell function. , 2013, Microvascular research.

[60]  E. Gonzalez de Mejia,et al.  Interactions between dietary flavonoids apigenin or luteolin and chemotherapeutic drugs to potentiate anti-proliferative effect on human pancreatic cancer cells, in vitro. , 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[61]  M. Malumbres,et al.  A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis , 2013, Cancer cell.

[62]  Tae-Jin Lee,et al.  Withaferin A inhibits matrix metalloproteinase-9 activity by suppressing the Akt signaling pathway. , 2013, Oncology reports.

[63]  M. Dimopoulos,et al.  Angiogenesis-Related Pathways in the Pathogenesis of Ovarian Cancer , 2013, International journal of molecular sciences.

[64]  Shihab Hasan,et al.  Inhibition of VEGF: a novel mechanism to control angiogenesis by Withania somnifera’s key metabolite Withaferin A , 2013, In Silico Pharmacology.

[65]  T. Efferth,et al.  Antiangiogenic Activity and Pharmacogenomics of Medicinal Plants from Traditional Korean Medicine , 2013, Evidence-based complementary and alternative medicine : eCAM.

[66]  L. Lessard,et al.  Large-scale independent validation of the nuclear factor-kappa B p65 prognostic biomarker in prostate cancer. , 2013, European journal of cancer.

[67]  H. Wakimoto,et al.  Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models. , 2013, Neoplasia.

[68]  V. Fokin,et al.  Novel VEGFR-2 kinase inhibitors identified by the back-to-front approach. , 2013, Bioorganic & medicinal chemistry letters.

[69]  B. Richelsen,et al.  Resveratrol has inhibitory effects on the hypoxia-induced inflammation and angiogenesis in human adipose tissue in vitro. , 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[70]  J. Buchner,et al.  Structure, Function and Regulation of the Hsp90 Machinery , 2013, Biomedical journal.

[71]  G. Brix,et al.  Regorafenib Inhibits Growth, Angiogenesis, and Metastasis in a Highly Aggressive, Orthotopic Colon Cancer Model , 2013, Molecular Cancer Therapeutics.

[72]  K. Matsubara,et al.  Marine algal carotenoids inhibit angiogenesis by down-regulating FGF-2-mediated intracellular signals in vascular endothelial cells , 2013, Molecular and Cellular Biochemistry.

[73]  Xiaoxin Zhu,et al.  Effects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis , 2013, Pharmacological reports : PR.

[74]  S. Chatterjee,et al.  Use of natural molecules as anti-angiogenic inhibitors for vascular endothelial growth factor receptor , 2012, Bioinformation.

[75]  M. Blumenkranz,et al.  Pharmacotherapy of Age-Related Macular Degeneration , 2012 .

[76]  R. Pestell,et al.  Cyclins and cell cycle control in cancer and disease. , 2012, Genes & cancer.

[77]  S. Jackson Hsp90: structure and function. , 2012, Topics in current chemistry.

[78]  M. Medina,et al.  Evaluation of the anti-angiogenic potential of hydroxytyrosol and tyrosol, two bio-active phenolic compounds of extra virgin olive oil, in endothelial cell cultures , 2012 .

[79]  S. Bir,et al.  Emerging role of PKA/eNOS pathway in therapeutic angiogenesis for ischaemic tissue diseases. , 2012, Cardiovascular research.

[80]  R. Hynes,et al.  An angiogenic role for the α5β1 integrin in promoting endothelial cell proliferation during cerebral hypoxia , 2012, Experimental Neurology.

[81]  K. Başer,et al.  Assessment of anti-angiogenic and anti-tumoral potentials of Origanum onites L. essential oil. , 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[82]  Yitao Wang,et al.  Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo. , 2012, Journal of ethnopharmacology.

[83]  R. Ernestus,et al.  A complete compilation of matrix metalloproteinase expression in human malignant gliomas. , 2012, World journal of clinical oncology.

[84]  P. Depreux,et al.  Synthesis and structure-activity relationships of (aryloxy)quinazoline ureas as novel, potent, and selective vascular endothelial growth factor receptor-2 inhibitors. , 2012, Journal of medicinal chemistry.

[85]  Emma E Vincent,et al.  Akt signalling in health and disease. , 2011, Cellular signalling.

[86]  Y. Shan,et al.  Recent advances in antiangiogenic agents with VEGFR as target. , 2011, Mini reviews in medicinal chemistry.

[87]  Y. Rojanasakul,et al.  Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway. , 2011, Biochemical and biophysical research communications.

[88]  Holger Gerhardt,et al.  Basic and Therapeutic Aspects of Angiogenesis , 2011, Cell.

[89]  S. Kong,et al.  Polyphyllin D, a steroidal saponin from Paris polyphylla, inhibits endothelial cell functions in vitro and angiogenesis in zebrafish embryos in vivo. , 2011, Journal of ethnopharmacology.

[90]  Ming Zhao,et al.  Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90 , 2011, Molecular Cancer.

[91]  K. Başer,et al.  Assessment of Anti-angiogenic and Anti-tumoral Potentials of Origanum onites L. Essential Oil , 2011 .

[92]  J. Scheller,et al.  The soluble Interleukin 6 receptor: generation and role in inflammation and cancer. , 2011, European journal of cell biology.

[93]  J. Scheller,et al.  The pro- and anti-inflammatory properties of the cytokine interleukin-6. , 2011, Biochimica et biophysica acta.

[94]  Xia Zhao,et al.  Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo. , 2011, Nanoscale.

[95]  N. Neamati,et al.  Integrin Targeted Therapeutics , 2011, Theranostics.

[96]  Rahmi Oklu,et al.  Angiogenesis and current antiangiogenic strategies for the treatment of cancer. , 2010, Journal of vascular and interventional radiology : JVIR.

[97]  O. Stoeltzing,et al.  Implication of heat shock protein 90 (HSP90) in tumor angiogenesis: a molecular target for anti-angiogenic therapy? , 2010, Current cancer drug targets.

[98]  Wei Wei,et al.  Clinical application and evaluation of anti-TNF-alpha agents for the treatment of rheumatoid arthritis , 2010, Acta Pharmacologica Sinica.

[99]  Jae-Yong Lee,et al.  Anti-angiogenic activity of methanol extract of Phellinus linteus and its fractions. , 2010, Journal of ethnopharmacology.

[100]  D. Jacobs,et al.  Extract of Oregano, Coffee, Thyme, Clove, and Walnuts Inhibits NF-κB in Monocytes and in Transgenic Reporter Mice , 2010, Cancer Prevention Research.

[101]  S. Indraccolo Interferon-α as angiogenesis inhibitor: Learning from tumor models , 2010, Autoimmunity.

[102]  Takahiko Horiuchi,et al.  Transmembrane TNF-α: structure, function and interaction with anti-TNF agents , 2010, Rheumatology.

[103]  Mazhar Adli,et al.  IKKα and IKKβ Each Function to Regulate NF-κB Activation in the TNF-Induced/Canonical Pathway , 2010, PloS one.

[104]  Howard P. Greisler,et al.  Molecular Mediators of Angiogenesis , 2010, Journal of burn care & research : official publication of the American Burn Association.

[105]  H. Verheul,et al.  Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action? , 2009, Angiogenesis.

[106]  Gerhard Christofori,et al.  The angiogenic switch in carcinogenesis. , 2009, Seminars in cancer biology.

[107]  Jin Hyoung Kim,et al.  Anti-angiogenic effect of caffeic acid on retinal neovascularization. , 2009, Vascular pharmacology.

[108]  M. Maraschin,et al.  Antiangiogenic properties of carotenoids: A potential role of maize as functional food , 2009 .

[109]  Patrick Schöffski,et al.  Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043). , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[110]  S. Capaccioli,et al.  Natural compounds for cancer treatment and prevention. , 2009, Pharmacological research.

[111]  Anindya Dutta,et al.  p21 in cancer: intricate networks and multiple activities , 2009, Nature Reviews Cancer.

[112]  H. Wakelee,et al.  Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer. , 2009, Current opinion in investigational drugs.

[113]  E Choy,et al.  Interleukin-6 as a key player in systemic inflammation and joint destruction. , 2009, Autoimmunity reviews.

[114]  R. Soares,et al.  Bmc Complementary and Alternative Medicine Anti-angiogenic Effects of Pterogynidine Alkaloid Isolated from Alchornea Glandulosa , 2009 .

[115]  Jin Hyoung Kim,et al.  Rosmarinic acid suppresses retinal neovascularization via cell cycle arrest with increase of p21(WAF1) expression. , 2009, European journal of pharmacology.

[116]  G. Kuttan,et al.  Anti-metastatic potential of Punarnavine, an alkaloid from Boerhaavia diffusa Linn. , 2009, Immunobiology.

[117]  S. Mousa,et al.  Introducing nanochemoprevention as a novel approach for cancer control: proof of principle with green tea polyphenol epigallocatechin-3-gallate. , 2009, Cancer research.

[118]  Bo Xu,et al.  Effect of beta-escin sodium on endothelial cells proliferation, migration and apoptosis. , 2008, Vascular pharmacology.

[119]  L. Pearl,et al.  Hsp90-Dependent Activation of Protein Kinases Is Regulated by Chaperone-Targeted Dephosphorylation of Cdc37 , 2008, Molecular cell.

[120]  Jianke Ren,et al.  Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice , 2008, BMC Immunology.

[121]  Yulun Huang,et al.  Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. , 2008, Cancer letters.

[122]  J. Patard,et al.  Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma. , 2008, European urology.

[123]  Yihai Cao,et al.  R Regulation of tumor angiogenesis and metastasis by FGF and PDGF signaling pathways , 2008, Journal of Molecular Medicine.

[124]  E. Basch,et al.  Targeted drugs for metastatic renal cell carcinoma , 2007, The Lancet.

[125]  J. Karp,et al.  Nanocarriers as an Emerging Platform for Cancer Therapy , 2022 .

[126]  S. Lee,et al.  Neovastat (Æ-941) inhibits the airway inflammation via VEGF and HIF-2α suppression , 2007 .

[127]  J. Ziello,et al.  Hypoxia-Inducible Factor (HIF)-1 Regulatory Pathway and its Potential for Therapeutic Intervention in Malignancy and Ischemia , 2007, The Yale journal of biology and medicine.

[128]  R. Tomanek Angiogenesis and Cardiovascular Diseases , 2007 .

[129]  J. Losso Screening Functional Foods as Inhibitors of Angiogenesis Biomarkers , 2007 .

[130]  E. Park,et al.  Anti-inflammatory and anti-angiogenic activities of Gastrodia elata Blume. , 2007, Journal of ethnopharmacology.

[131]  J. Alao,et al.  Molecular Cancer BioMed Central Review The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention , 2007 .

[132]  B. Aggarwal,et al.  Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation. , 2007, Blood.

[133]  Apurva A Desai,et al.  Sorafenib in advanced clear-cell renal-cell carcinoma. , 2007, The New England journal of medicine.

[134]  C. Lindley,et al.  Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies. , 2006, Clinical therapeutics.

[135]  Michael Karin,et al.  Regulation and Function of IKK and IKK-Related Kinases , 2006, Science's STKE.

[136]  Weimin Guo,et al.  Green tea catechin, epigallocatechin‐3‐gallate, inhibits vascular endothelial growth factor angiogenic signaling by disrupting the formation of a receptor complex , 2006, International journal of cancer.

[137]  A. Eggermont,et al.  TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility. , 2006, The oncologist.

[138]  D. Haller,et al.  Functional diversity of flavonoids in the inhibition of the proinflammatory NF-kappaB, IRF, and Akt signaling pathways in murine intestinal epithelial cells. , 2006, The Journal of nutrition.

[139]  S. Sagar,et al.  Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer—Part 1 , 2006, Current oncology.

[140]  Napoleone Ferrara,et al.  Angiogenesis as a therapeutic target , 2005, Nature.

[141]  P. Schumacker,et al.  Hypoxia-inducible factor-1 (HIF-1). , 2005, Critical care medicine.

[142]  M. Diederich,et al.  Chemopreventive and therapeutic effects of curcumin. , 2005, Cancer letters.

[143]  Hua Li,et al.  Genistein inhibited retinal neovascularization and expression of vascular endothelial growth factor and hypoxia inducible factor 1alpha in a mouse model of oxygen-induced retinopathy. , 2005, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

[144]  D. Gingras,et al.  Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound. , 2005, Carcinogenesis.

[145]  S. Percival,et al.  Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells. , 2005, Cancer letters.

[146]  Laurence H Pearl,et al.  Hsp90 and Cdc37 -- a chaperone cancer conspiracy. , 2005, Current opinion in genetics & development.

[147]  H. Hammers,et al.  Withaferin A is a potent inhibitor of angiogenesis , 2004, Angiogenesis.

[148]  M. Karin,et al.  The two NF-κB activation pathways and their role in innate and adaptive immunity , 2004 .

[149]  G. Williamson,et al.  Quercetin metabolites downregulate cyclooxygenase-2 transcription in human lymphocytes ex vivo but not in vivo. , 2004, The Journal of nutrition.

[150]  S. Mazumder,et al.  A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapy. , 2004, Current cancer drug targets.

[151]  S. Percival,et al.  Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells. , 2003, The Journal of nutrition.

[152]  K. Bhoola,et al.  Natural products for cancer prevention: a global perspective. , 2003, Pharmacology & therapeutics.

[153]  J. Pelletier,et al.  Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs , 2003, Annals of the rheumatic diseases.

[154]  P. Carmeliet Angiogenesis in health and disease , 2003, Nature Medicine.

[155]  N. Ferrara,et al.  The biology of VEGF and its receptors , 2003, Nature Medicine.

[156]  R. Visse,et al.  This Review Is Part of a Thematic Series on Matrix Metalloproteinases, Which Includes the following Articles: Matrix Metalloproteinase Inhibition after Myocardial Infarction: a New Approach to Prevent Heart Failure? Matrix Metalloproteinases in Vascular Remodeling and Atherogenesis: the Good, the Ba , 2022 .

[157]  RobertVisse,et al.  Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases , 2003 .

[158]  B. Wiedenmann,et al.  Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis. , 2003, Journal of the National Cancer Institute.

[159]  Jin-Rong Zhou,et al.  Soy phytochemicals and tea bioactive components synergistically inhibit androgen-sensitive human prostate tumors in mice. , 2003, The Journal of nutrition.

[160]  D. Sauder,et al.  Neovastat (AE-941), an inhibitor of angiogenesis: Randomized phase I/II clinical trial results in patients with plaque psoriasis. , 2002, Journal of the American Academy of Dermatology.

[161]  K. Kaji,et al.  Resveratrol and quercetin inhibit angiogenesis in vitro. , 2001, Cancer letters.

[162]  Yihai Cao,et al.  Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[163]  F. Grosso,et al.  Inhibition of angiogenesis and vascular tumor growth by interferon-producing cells: A gene therapy approach. , 2000, The American journal of pathology.

[164]  M. Isemura,et al.  Effects of tea polyphenols on the invasion and matrix metalloproteinases activities of human fibrosarcoma HT1080 cells. , 1999, Journal of agricultural and food chemistry.

[165]  H. Matsuda,et al.  Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals. , 1997, Biological & pharmaceutical bulletin.

[166]  Y. Zou,et al.  Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. , 1997, The Journal of clinical investigation.

[167]  U. Otten,et al.  Interleukin-6 (IL-6)—A molecule with both beneficial and destructive potentials , 1997, Progress in Neurobiology.

[168]  R. D'Amato,et al.  Thalidomide is an inhibitor of angiogenesis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[169]  A. Logan,et al.  Angiogenesis , 1993, The Lancet.

[170]  A. Mantovani,et al.  Cytokine regulation of endothelial cell function , 1992, Behring Institute Mitteilungen.

[171]  M. Vallet‐Regí,et al.  Effects of bleaching on osteoclast activity and their modulation by osteostatin and fibroblast growth factor 2. , 2016, Journal of colloid and interface science.

[172]  A. Salajegheh Cyclin D1 and E1 , 2016 .

[173]  D. Reglodi,et al.  Neuropeptides, trophic factors, and other substances providing morphofunctional and metabolic protection in experimental models of diabetic retinopathy. , 2014, International review of cell and molecular biology.

[174]  Yitao Wang,et al.  Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation , 2014, AAPS PharmSciTech.

[175]  Joan W. Miller,et al.  Chapter 26 – Basic Mechanisms of Pathological Retinal and Choroidal Angiogenesis , 2013 .

[176]  G. Klement,et al.  The Role of Platelets in Angiogenesis , 2013 .

[177]  K. Rissanen,et al.  A novel caryophyllene type sesquiterpene lactone from Asparagus falcatus (Linn.); structure elucidation and anti-angiogenic activity on HUVECs. , 2012, European journal of medicinal chemistry.

[178]  B. Salimath,et al.  Withaferin A suppresses the expression of vascular endothelial growth factor in Ehrlich ascites tumor cells via Sp1 transcription factor , 2009 .

[179]  S. Raychaudhuri,et al.  Angiogenesis in inflammatory arthritis , 2007 .

[180]  S. Seregard,et al.  CHAPTER 3 – Cancer pathology and angiogenesis , 2007 .

[181]  A. Eggermont,et al.  TNF-α in Cancer Treatment : Molecular Insights , Antitumor Effects , and Clinical Utility , 2006 .

[182]  C. Sen,et al.  Anti-angiogenic, Antioxidant, and Anti-carcinogenic Properties of a Novel Anthocyanin-Rich Berry Extract Formula , 2004, Biochemistry (Moscow).

[183]  G. Blackburn,et al.  Combined inhibition of estrogen‐dependent human breast carcinoma by soy and tea bioactive components in mice , 2004, International journal of cancer.

[184]  M. Karno,et al.  Renal cell carcinoma. , 1956, Bulletin. Tufts-New England Medical Center.