Systemic Inflammation with Multiorgan Dysfunction Is the Cause of Death in Murine Ligation-Induced Acute Pancreatitis

[1]  D. Meyerholz,et al.  A Novel Model of Severe Gallstone Pancreatitis: Murine Pancreatic Duct Ligation Results in Systemic Inflammation and Substantial Mortality , 2010, Pancreatology.

[2]  D. Williard,et al.  Dominant Negative p38 Mitogen-Activated Protein Kinase Expression Inhibits NF-ĸB Activation in AR42J Cells , 2010, Pancreatology.

[3]  G. Gores,et al.  Overexpression of Mcl-1 Attenuates Liver Injury and Fibrosis in the Bile Duct–Ligated Mouse , 2009, Digestive Diseases and Sciences.

[4]  D. Meyerholz,et al.  Murine pancreatic duct ligation induces stress kinase activation, acute pancreatitis, and acute lung injury. , 2008, American journal of surgery.

[5]  G. Gores,et al.  TRAIL mediates liver injury by the innate immune system in the bile duct–ligated mouse , 2008, Hepatology.

[6]  I. Samuel.  Bile and pancreatic juice exclusion activates acinar stress kinases and exacerbates gallstone pancreatitis. , 2008, Surgery.

[7]  L. Tephly,et al.  Enteral Exclusion Increases Map Kinase Activation and Cytokine Production in a Model of Gallstone Pancreatitis , 2008, Pancreatology.

[8]  P. Hegyi,et al.  The role of NF-κB activation in the pathogenesis of acute pancreatitis , 2007, Gut.

[9]  R. Fisher,et al.  In vitro evidence for role of ERK, p38, and JNK in exocrine pancreatic cytokine production , 2006, Journal of Gastrointestinal Surgery.

[10]  A. Zaheer,et al.  Bile-Pancreatic Juice Exclusion Increases p38MAPK Activation and TNF-α Production in Ligation-Induced Acute Pancreatitis in Rats , 2005, Pancreatology.

[11]  C. Johnson,et al.  Painful ascites , 2004, Gut.

[12]  S. Moochhala,et al.  Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome , 2004, The Journal of pathology.

[13]  L. Boquist,et al.  Ultrastructure of pancreatic acinar and islet parenchyma in rats at various intervals after duct ligation , 2004, Virchows Archiv A.

[14]  S. Pandol,et al.  Curcumin ameliorates ethanol and nonethanol experimental pancreatitis. , 2003, American journal of physiology. Gastrointestinal and liver physiology.

[15]  Jun Yang,et al.  Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: The role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-κB , 2003, Journal of Gastrointestinal Surgery.

[16]  S. Mastorides,et al.  Pancreatic elastase induces liver injury by activating cytokine production within Kupffer cells via nuclear factor-kappa B , 2002, Journal of Gastrointestinal Surgery.

[17]  B. Han,et al.  NF-κB activation in pancreas induces pancreatic and systemic inflammatory response , 2002 .

[18]  B. Han,et al.  NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response. , 2002, Gastroenterology.

[19]  B. Rau,et al.  Early Severe Acute Pancreatitis: Characteristics of a New Subgroup , 2001, Pancreas.

[20]  John A. Williams,et al.  Stress kinases and heat shock proteins in the pancreas: possible roles in normal function and disease , 2000, Journal of Gastroenterology.

[21]  S. Evans,et al.  High early mortality rate from acute pancreatitis in Scotland, 1984–1995 , 1999, The British journal of surgery.

[22]  M. Zinner,et al.  Relationship of necrosis to organ failure in severe acute pancreatitis. , 1997, Gastroenterology.

[23]  A. Dąbrowski,et al.  Stress-activated protein kinase activation is the earliest direct correlate to the induction of secretagogue-induced pancreatitis in rats. , 1996, Biochemical and biophysical research communications.

[24]  D. Carter,et al.  Factors influencing morbidity and mortality in acute pancreatitis; an analysis of 279 cases. , 1995, Gut.

[25]  A. Kingsnorth,et al.  Experimental models of acute pancreatitis , 1994, The British journal of surgery.

[26]  P. Banks,et al.  Prognostic factors in sterile pancreatic necrosis. , 1992, Gastroenterology.

[27]  J. C. Vuletin,et al.  A Light and Electron Microscopic Study , 1976 .

[28]  A. Churg,et al.  Early changes in the exocrine pancreas of the dog and rat after ligation of the pancreatic duct. A light and electron microscopic study. , 1971, The American journal of pathology.