Bioconjugation of holo-transferrin with hypoxia-enhanced fluorescent sensor for the selective imaging of cancer cells

[1]  Zilin Chen,et al.  A pH-sensitive carbonic anhydrase Ⅸ-targeted near-infrared probe for fluorescent sensing and imaging of hypoxic osteosarcoma , 2022, Sensors and Actuators B: Chemical.

[2]  Lin Li,et al.  Mitochondria-specific two-photon fluorogenic probe for simultaneously visualizing nitroreductase and viscosity in cancer cells , 2022, Sensors and Actuators B: Chemical.

[3]  Yueqing Gu,et al.  Ultrasensitive near-infrared fluorescence probe activated by nitroreductase for in vivo hypoxia detection , 2022, Sensors and Actuators B: Chemical.

[4]  Yuxun Lu,et al.  Optical Monitoring And Treatment of Breast Cancer By a Tumor Hypoxia-Activated Multi-Functional Fluorescent Sensor , 2022, SSRN Electronic Journal.

[5]  Fengfeng Xue,et al.  NTR and O2 programmed responsive photogenic radicals for efficient hypoxia cancer therapy , 2022, Sensors and Actuators B: Chemical.

[6]  Olga Mazuryk,et al.  Significance of Specific Oxidoreductases in the Design of Hypoxia-Activated Prodrugs and Fluorescent Turn off–on Probes for Hypoxia Imaging , 2022, Cancers.

[7]  D. Hanahan Hallmarks of Cancer: New Dimensions. , 2022, Cancer discovery.

[8]  Tao Chen,et al.  Visualizing the hypoxic heterogeneity for distinguishing the cancer tissues with a two-photon nitroreductase-H2S logic probe via intramolecular isomerization , 2021 .

[9]  N. Chopin,et al.  Nitro-Pyrazinotriazapentalene scaffolds– nitroreductase quantification and in vitro fluorescence imaging of hypoxia , 2021 .

[10]  Xiao-Qun Cao,et al.  A novel near-infrared fluorescence off-on probe for imaging hypoxia and nitroreductase in cells and in vivo , 2021, Sensors and Actuators B: Chemical.

[11]  Yue Li,et al.  Targeting Hypoxia: Hypoxia-Activated Prodrugs in Cancer Therapy , 2021, Frontiers in Oncology.

[12]  H. Hua,et al.  Small-molecule probes for fluorescent detection of cellular hypoxia-related nitroreductase. , 2021, Journal of pharmaceutical and biomedical analysis.

[13]  N. Chopin,et al.  Pyridazino-1,3a,6a-Triazapentalenes as Versatile Fluorescent Probes: Impact of Their Post-Functionalization and Application for Cellular Imaging , 2021, International journal of molecular sciences.

[14]  E. Rosenthal,et al.  Real-time fluorescence imaging in intraoperative decision making for cancer surgery. , 2021, The Lancet. Oncology.

[15]  M. Penichet,et al.  Antibodies Targeting the Transferrin Receptor 1 (TfR1) as Direct Anti-cancer Agents , 2021, Frontiers in Immunology.

[16]  Yeong Mi Lee,et al.  A Study on Hypoxia Susceptibility of Organ Tissues by Fluorescence Imaging with a Ratiometric Nitroreductase Probe. , 2020, ACS sensors.

[17]  Hai‐Liang Zhu,et al.  Recent progress in the design principles, sensing mechanisms, and applications of small-molecule probes for nitroreductases , 2020 .

[18]  E. Petersson,et al.  Rational design of small molecule fluorescent probes for biological applications. , 2020, Organic & biomolecular chemistry.

[19]  E. Graves,et al.  An Activatable NIR Fluorescent Rosol for Selectively Imaging Nitroreductase Activity. , 2020, Sensors and actuators. B, Chemical.

[20]  G. Guillaumet,et al.  Intramolecular Metal Free N-N Bond Formation with Heteroaromatic Amines: Mild Access to Fused-Triazapentalene Derivatives. , 2019, Chemistry.

[21]  Bifeng Liu,et al.  A fluorescence turn-on biosensor based on transferrin encapsulated gold nanoclusters for 5-hydroxytryptamine detection , 2019, Sensors and Actuators B: Chemical.

[22]  N. Chopin,et al.  An original class of small sized molecules as versatile fluorescent probes for cellular imaging. , 2019, Chemical communications.

[23]  R. Mason,et al.  Kinetics-Based Measurement of Hypoxia in Living Cells and Animals Using an Acetoxymethyl Ester Chemiluminescent Probe. , 2019, ACS sensors.

[24]  B. Liu,et al.  A novel fluorescent turn-on probe for highly selective detection of nitroreductase in tumor cells , 2018, Sensors and Actuators B: Chemical.

[25]  Bert van der Vegt,et al.  Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers , 2018, Nature Communications.

[26]  I. Amelio,et al.  The hypoxic tumour microenvironment , 2018, Oncogenesis.

[27]  J. Jaworski,et al.  Luminescent Probe Based Techniques for Hypoxia Imaging. , 2017, Journal of nanomedicine research.

[28]  M. Landry,et al.  A Probe for the Detection of Hypoxic Cancer Cells. , 2017, ACS sensors.

[29]  Jianlin Shi,et al.  Chemical Design and Synthesis of Functionalized Probes for Imaging and Treating Tumor Hypoxia. , 2017, Chemical reviews.

[30]  S. Matile,et al.  Strained Cyclic Disulfides Enable Cellular Uptake by Reacting with the Transferrin Receptor. , 2017, Journal of the American Chemical Society.

[31]  N. Harlaar,et al.  Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: a single-centre feasibility study. , 2016, The lancet. Gastroenterology & hepatology.

[32]  H. Kolb,et al.  The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities. , 2014, Antioxidants & redox signaling.

[33]  Stephanie M. Tortorella,et al.  Transferrin Receptor-Mediated Endocytosis: A Useful Target for Cancer Therapy , 2014, The Journal of Membrane Biology.

[34]  Jonghan Kim,et al.  Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo , 2013, PloS one.

[35]  A. Vahrmeijer,et al.  Optical Image-Guided Cancer Surgery: Challenges and Limitations , 2013, Clinical Cancer Research.

[36]  M. Hentze,et al.  The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption. , 2013, Cell metabolism.

[37]  Ezequiel Bernabeu,et al.  The transferrin receptor and the targeted delivery of therapeutic agents against cancer. , 2012, Biochimica et biophysica acta.

[38]  G. Semenza,et al.  Hypoxia-Inducible Factors in Physiology and Medicine , 2012, Cell.

[39]  P. Low,et al.  Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results , 2011, Nature Medicine.

[40]  W. Wheaton,et al.  Hypoxia. 2. Hypoxia regulates cellular metabolism. , 2011, American journal of physiology. Cell physiology.

[41]  Mary E Napier,et al.  The complex role of multivalency in nanoparticles targeting the transferrin receptor for cancer therapies. , 2010, Journal of the American Chemical Society.

[42]  S. Kizaka-Kondoh,et al.  Significance of nitroimidazole compounds and hypoxia‐inducible factor‐1 for imaging tumor hypoxia , 2009, Cancer science.

[43]  J. Leger,et al.  An efficient route to polynitrogen-fused tricycles via a nitrene-mediated N–N bond formation under microwave irradiation , 2008 .

[44]  L. Fass Imaging and cancer: A review , 2008, Molecular oncology.

[45]  M. Wessling-Resnick,et al.  The small-molecule iron transport inhibitor ferristatin/NSC306711 promotes degradation of the transferrin receptor. , 2008, Chemistry & biology.

[46]  P. Maxwell The HIF pathway in cancer. , 2005, Seminars in cell & developmental biology.

[47]  R. Koder,et al.  Structures of Nitroreductase in Three States , 2002, The Journal of Biological Chemistry.

[48]  D. Richardson,et al.  The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells. , 1997, Biochimica et biophysica acta.

[49]  P. Aisen,et al.  Stoichiometric and site characteristics of the binding of iron to human transferrin. , 1978, The Journal of biological chemistry.

[50]  P. Shang,et al.  Transferrin receptor 1 in cancer: a new sight for cancer therapy. , 2018, American journal of cancer research.