14th International HLA and Immunogenetics Workshop: report on KIR receptors and their applications.

During the last few years many laboratories have developed a keen interest in detecting killer immunoglobulin-like receptor (KIR) receptor genes in various populations, diseases and in stem cell transplantation. At the 14th International Histocompatibility Workshop held in Melbourne in December 2006, many of these laboratories presented their findings at a special session. To introduce this work, we provide an introduction to KIR receptors and an outline of previous applications of KIR receptor typing prior to the Workshop.

[1]  C. Witt,et al.  The relevance of natural killer cell human leucocyte antigen epitopes and killer cell immunoglobulin‐like receptors in bone marrow transplantation , 2006, Vox sanguinis.

[2]  M. Carrington,et al.  The impact of variation at the KIR gene cluster on human disease. , 2006, Current topics in microbiology and immunology.

[3]  Peter Parham,et al.  Complex interactions: the immunogenetics of human leukocyte antigen and killer cell immunoglobulin-like receptors. , 2005, Seminars in hematology.

[4]  P. Parham MHC class I molecules and kirs in human history, health and survival , 2005, Nature Reviews Immunology.

[5]  L. Lanier,et al.  Viral modulation of NK cell immunity , 2005, Nature Reviews Microbiology.

[6]  Salim I. Khakoo,et al.  HLA and NK Cell Inhibitory Receptor Genes in Resolving Hepatitis C Virus Infection , 2004, Science.

[7]  B. Koeleman,et al.  KIR in type 1 diabetes: disparate distribution of activating and inhibitory natural killer cell receptors in patients versus HLA-matched control subjects. , 2003, Diabetes.

[8]  M. Carrington,et al.  Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002. , 2003, Immunogenetics.

[9]  Michael J. Wilson,et al.  Cutting Edge: Susceptibility to Psoriatic Arthritis: Influence of Activating Killer Ig-Like Receptor Genes in the Absence of Specific HLA-C Alleles1 , 2002, The Journal of Immunology.

[10]  D. Middleton,et al.  Natural killer cells and their receptors. , 2002, Transplant immunology.

[11]  Peter Parham,et al.  Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B , 2002, Immunogenetics.

[12]  Katia Perruccio,et al.  Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants , 2002, Science.

[13]  Peter Parham,et al.  KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. , 2002, Annual review of immunology.

[14]  C. Biron,et al.  NK cells and NKT cells in innate defense against viral infections. , 2001, Current opinion in immunology.

[15]  R. Vaughan,et al.  Distribution of natural killer cell immunoglobulin-like receptor sequences in three ethnic groups , 2001, Immunogenetics.

[16]  R. Biassoni,et al.  Human NK-cell receptors. , 2000, Immunology today.

[17]  S. Beck,et al.  Plasticity in the organization and sequences of human KIR/ILT gene families. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[18]  F. Christiansen,et al.  The genomic organization and evolution of the natural killer immunoglobulin-like receptor (KIR) gene cluster , 2000, Immunogenetics.

[19]  H. Ljunggren,et al.  In search of the 'missing self': MHC molecules and NK cell recognition. , 1990, Immunology today.

[20]  G. Trinchieri,et al.  Biology of Natural Killer Cells , 1989, Advances in Immunology.