MYELOID NEOPLASIA Caspase-3 controls AML 1-ETO – driven leukemogenesis via autophagy modulation in a ULK 1-dependent manner
暂无分享,去创建一个
Saijuan Chen | Zhu Chen | F. Liu | Ming Sun | S. Nimer | Bing Chen | Lan Wang | N. Man | Mingjiang Xu | Yurong Tan | Xiaojian Sun | Feng-Chun Yang | K. Ando | Dan Hou | S. Greenblatt | Daniel L. Karl | Guoyan Cheng | C. Martinez | Fan Liu | D. Hou
[1] V. Vacic,et al. Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles , 2016, The Journal of experimental medicine.
[2] D. Ferguson,et al. Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia , 2015, Cell Death Discovery.
[3] John M Asara,et al. Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates. , 2015, Molecular cell.
[4] C. Baldus,et al. Outlook on PI3K/AKT/mTOR inhibition in acute leukemia , 2015, Molecular and Cellular Therapies.
[5] E. Sausville,et al. Autophagy modulation: a target for cancer treatment development , 2015, Cancer Chemotherapy and Pharmacology.
[6] Jessica L. Larson,et al. Caspase-3 Deficiency Results in Disrupted Synaptic Homeostasis and Impaired Attention Control , 2015, The Journal of Neuroscience.
[7] Jiong Hu,et al. Autophagy Is an Important Event for Low Dose Cytarabine Treatment in Acute Myeloid Leukemia U937 Cell Line , 2014 .
[8] T. Martinović,et al. Idarubicin induces mTOR-dependent cytotoxic autophagy in leukemic cells. , 2014, Experimental cell research.
[9] L. Zitvogel,et al. An autophagy-dependent anticancer immune response determines the efficacy of melanoma chemotherapy , 2014, Oncoimmunology.
[10] J. DeVoss,et al. A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3 , 2014, Nature.
[11] M. Torgersen,et al. Autophagy: friend or foe in the treatment of fusion protein-associated leukemias? , 2013, Autophagy.
[12] N. Engedal,et al. Targeting autophagy potentiates the apoptotic effect of histone deacetylase inhibitors in t(8;21) AML cells. , 2013, Blood.
[13] David R McIlwain,et al. Caspase functions in cell death and disease. , 2013, Cold Spring Harbor perspectives in biology.
[14] N. Yuan,et al. Chinese a Nti鄄 Cancer a Ssociation , 2022 .
[15] M. Overholtzer,et al. Interaction Between FIP200 and ATG16L1 Distinguishes ULK1 Complex-Dependent and -Independent Autophagy , 2012, Nature Structural &Molecular Biology.
[16] S. Nimer,et al. AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches , 2012, Frontiers of Medicine.
[17] Sangeeta Khare,et al. Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition) , 2016 .
[18] Robert Clarke,et al. Guidelines for the use and interpretation of assays for monitoring autophagy , 2012 .
[19] Chuanfeng Wu,et al. Targeting of AML1-ETO in t(8;21) Leukemia by Oridonin Generates a Tumor Suppressor–Like Protein , 2012, Science Translational Medicine.
[20] N. Mizushima,et al. The role of Atg proteins in autophagosome formation. , 2011, Annual review of cell and developmental biology.
[21] Shengbing Huang,et al. The Role of Autophagy in Cancer: Therapeutic Implications , 2011, Molecular Cancer Therapeutics.
[22] D. Fingar,et al. ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding , 2011, Autophagy.
[23] Guoqiang Chen,et al. Effector Caspases and Leukemia , 2011, International journal of cell biology.
[24] D. Tang,et al. Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein , 2011, Autophagy.
[25] Quan Chen,et al. Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis , 2010, Protein & Cell.
[26] N. Mizushima,et al. The role of the Atg1/ULK1 complex in autophagy regulation. , 2010, Current opinion in cell biology.
[27] G. Smyth,et al. ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays. , 2009, Journal of immunological methods.
[28] J. Lane,et al. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis , 2009, Journal of Cell Science.
[29] D. Teachey,et al. Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies , 2009, British journal of haematology.
[30] R A Knight,et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes , 2009, Cell Death and Differentiation.
[31] P. Greaney,et al. The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies. , 2009, Blood.
[32] Y. Akao,et al. Intracellular glutathione regulates sesquiterpene lactone-induced conversion of autophagy to apoptosis in human leukemia HL60 cells. , 2009, Anticancer research.
[33] Yuh‐Cheng Yang,et al. Platonin induces autophagy-associated cell death in human leukemia cells , 2009, Autophagy.
[34] M. Lübbert,et al. Complementing mutations in core binding factor leukemias: from mouse models to clinical applications , 2008, Oncogene.
[35] Ying Zhao,et al. Vitamin D3 Induces Autophagy of Human Myeloid Leukemia Cells* , 2008, Journal of Biological Chemistry.
[36] M. Abdul-Ghani,et al. Rehabilitation of a contract killer: caspase-3 directs stem cell differentiation. , 2008, Cell stem cell.
[37] M. Kyba,et al. Caspase activity mediates the differentiation of embryonic stem cells. , 2008, Cell stem cell.
[38] S. Karlsson,et al. Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3. , 2008, Cell stem cell.
[39] N. Mizushima,et al. Autophagy: process and function. , 2007, Genes & development.
[40] Ming Yan,et al. The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO. , 2007, Blood.
[41] Ming Yan,et al. Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo. , 2007, Blood.
[42] YongSung Kim,et al. ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase , 2007, EMBO reports.
[43] R. Henschler,et al. Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells. , 2007, Haematologica.
[44] Huiping Sun,et al. Eriocalyxin B induces apoptosis of t(8;21) leukemia cells through NF-κB and MAPK signaling pathways and triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent manner , 2007, Cell Death and Differentiation.
[45] H. Sakagami,et al. Induction of non-apoptotic cell death by morphinone in human promyelocytic leukemia HL-60 cells. , 2006, Anticancer research.
[46] M. Minden,et al. Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients. , 2006, Experimental hematology.
[47] Ming Yan,et al. A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis , 2006, Nature Medicine.
[48] C. Récher,et al. mTOR, a new therapeutic target in acute myeloid leukemia. , 2005, Cell cycle.
[49] S. Nimer,et al. Effects of the leukemia-associated AML1-ETO protein on hematopoietic stem and progenitor cells , 2004, Oncogene.
[50] C. Zeiss,et al. Caspase-3 in postnatal retinal development and degeneration. , 2004, Investigative ophthalmology & visual science.
[51] T. Mak,et al. Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity , 2003, Nature Immunology.
[52] R. Flavell,et al. Strain‐Dependent Neurodevelopmental Abnormalities in Caspase‐3‐Deficient Mice , 2002, Journal of neuropathology and experimental neurology.
[53] J. Downing,et al. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia. , 2002, Cancer cell.
[54] I. Weissman,et al. AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[55] Xuening Wang,et al. Carnosic acid and promotion of monocytic differentiation of HL60-G cells initiated by other agents. , 2001, Journal of the National Cancer Institute.
[56] D. Tenen,et al. Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model. , 2000, Blood.
[57] R. Sékaly,et al. Early Activation of Caspases during T Lymphocyte Stimulation Results in Selective Substrate Cleavage in Nonapoptotic Cells , 1999, The Journal of experimental medicine.
[58] J. Tschopp,et al. Caspase Activation Is Required for T Cell Proliferation , 1999, The Journal of experimental medicine.
[59] A. Porter,et al. Emerging roles of caspase-3 in apoptosis , 1999, Cell Death and Differentiation.
[60] A. Matsuura,et al. Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. , 1997, Gene.
[61] F. Fassy,et al. Evidence for CPP32 Activation in the Absence of Apoptosis during T Lymphocyte Stimulation* , 1997, The Journal of Biological Chemistry.
[62] Keisuke Kuida,et al. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice , 1996, Nature.
[63] C. Kenific,et al. Cellular and metabolic functions for autophagy in cancer cells. , 2015, Trends in cell biology.
[64] G. Kroemer,et al. NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia. , 2007, Oncogene.
[65] P. Thall,et al. Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia. , 1998, Blood.